Jeff Ruffolo
@jeffruffolo.bsky.social
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Protein Design / ML @ Profluent Bio | Molecular Biophysics PhD @ Johns Hopkins
What does pushing the boundaries of model capacity and data scale do for generative protein language models? I’m super excited to share our latest work at Profluent Bio where we begin to explore and test some of our hypotheses!
www.biorxiv.org/content/10.1...
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Scaling unlocks broader generation and deeper functional understanding of proteins
Generative protein language models (PLMs) are powerful tools for designing proteins purpose-built to solve problems in medicine, agriculture, and industrial processes. Recent work has trained ever lar...
https://www.biorxiv.org/content/10.1101/2025.04.15.649055v1
6 months ago
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I’ll be in Vancouver for NeurIPS December 13-16, reach out if you’re interested in protein language models, genome editor / antibody design, or any of the other cool stuff we’re doing at Profluent!
10 months ago
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