(1/4) In IBIS (ibis.autosome.org), we challenged teams from all over the world to decipher the DNA recognition code of human transcription factors. Today, we are excited to announce the Final IBIS Conference scheduled for November 27, 2024.

(2/12) The human genome encodes ~1.5 thousand transcription factors (TFs), and hundreds of them still lack "DNA motifs", i.e., compact human- and machine-readable representations of the TF-DNA binding specificity.

(3/12) There are a multitude of high-throughput methods for assessing the DNA binding specificity of transcription factors. The variety of existing motif discovery tools is even greater. Which one to use?

(1/12) Excited to present the results of the large-scale benchmarking of DNA motif discovery tools using the Codebook data compendium on poorly studied human transcription factors and the Codebook Motif Explorer: dx.doi.org/10.1101/2024..., mex.autosome.org ⬇️.