Farnaby Research Group (@farnabygroup.bsky.social)

Excited to share the Farnaby Group’s first pre-print, detailing our approach to plate-based bifunctional chemical probe discovery, identifying a brain active PROTAC directly from a single screen. 1/7 chemrxiv.org/engage/chemr...

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Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening Bifunctional targeted protein degraders, also known as Proteolysis Targeting Chimeras (PROTACs), are an emerging drug modality that may offer a new approach to understand and treat neurodegenerative d... https://chemrxiv.org/engage/chemrxiv/article-details/67ca159581d2151a0265b786