Cell type-specific calcium imaging of central sensitization in mouse dorsal horn www.nature.com/articles/s41... Allodynia is a state in which pain is elicited by innocuous stimuli, for example in response to cutaneous capsaicin application. This phenomenon is mediated by spinal cord /1

Diverse firing properties and Ab-, Ad-, and C-afferent inputs of small local circuit neurons in spinal lamina I pubmed.ncbi.nlm.nih.gov/26797505/ More than 90% of neurons in lamina I are interneurons with unknown circuitry. In this article these neurons (47) were examined using various techniques /1

Neuronal circuitry for pain processing in the dorsal horn www.nature.com/articles/nrn... Dorsal horn receives both noxious and non-noxious stimuli from different body parts. These stimuli are further processed by interneurons and transmitted to the brain by projection neurons. /1

Kappa Opioid Receptor Distribution and Function in Primary Afferents pubmed.ncbi.nlm.nih.gov/30236284/ It`s known that KORs (kappa opioid receptors) are expressed in primary afferents. In this study it is shown that KORs are expressed in peptidergic sensory neurons and in low-threshold/1

Ultrasensitive fluorescent proteins for imaging neuronal activity In this study GCaMP6 a new calcium was developed and tested in mice, zebrafish and flies. In layers 2 and 3 of pyramidal visual cortex GCaMP6 detected single APs in somata and transients in spines. www.nature.com/articles/nat... /1

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP pubmed.ncbi.nlm.nih.gov/11086982/ In this article 4 fluorescent proteins (red, green, yellow, cyan) also called XFPs, were introduced to create 25 transgenic lines of mice. /1

Imaging Neural Activity Using Thy1-GCaMP Transgenic Mice pubmed.ncbi.nlm.nih.gov/23083733/ This publication charactarized expression of GCaMP under Thy1 promoter in neuronal subpopulations. Calcium imaging offers a great opportunity to observe neuronal activity in subpopulations of intact neurons/1

Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn. physoc.onlinelibrary.wiley.com/doi/full/10.... TRPA1, TRPM3 partially overlap with TRPV1 expression in sensory neurons. /1

Cycle 5 Buzsáki's Rhythms of the Brain: Cycle 5 1. General Summary Even without any sensory input brain supports self-generated, spontaneous order. Neural connectivity constantly generates short-lived transient oscillations. Oscillations in the mammalian brain range from from minutes to 600 Hz. /1

Cycle 4 Buzsáki's Rhythms of the Brain: Cycle 4 1. General Summary Every tool in neuroscience research compromises between the ideal temporal and spatial resolution. Ideal temporal scale is in milliseconds, spatial -- from global scale of the brain to spines of individual neurons. 1/

Cycle 3 Buzsáki's Rhythms of the Brain: Cycle 3 1. General Summary Only excitatory interactions (like collision in classical thermodynamics) are not viable in the brain, they would just create avalanches of excitation. To maintain "tensegrical" dynamic, there should be inhibitory forces. 1/

Anyone can recommend an interesting review on optical illusions? I am primarily interested in how they are connected with how our visual systems are tuned to process natural scenes #optical_illusions #askacademia

Cycle 2 Buzsáki's Rhythms of the Brain: Cycle 2 1. General Summary To understand brain function we need to use empirical approach as well as morphological. The bigger neuronal systems become the more challenging they are to wire while preserving computational ability 1/

Buzsáki's Rhythms of the Brain: Cycle 1 1. General Summary Brain waves are mostly prominent when we are dreaming, and serendipitously, the first brain oscillations in humans were recorded because of a dream. 1/

Buzsáki's Rhythms of the Brain: Prelude 1. General Summary This chapter provides a glimpse into the author's motivation for writing the book, along with personal experiences and an overview of its structure. A good place to decide whether you want to read it or not. 1/

a thread of threads

sciencedirect.com/science/arti... 1. General summary This paper offers a good overview of the idea of waves in the brain and how they are different from brain states. Introducing waves helps to view brain dynamics more as a continuum and allows to 1/

Thread structure: