Dan Sarni
@dansarni.bsky.social
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Postdoc in the Jackson lab @mrc_hgu. Genome instability, DNA methylation and replication
reposted by
Dan Sarni
Institute of Genetics and Cancer
20 days ago
A new study has identified a rare genetic condition which causes individuals to age at a faster rate than normal, shining a light on the mechanisms of aging. This study was jointly supervised by Kevin Myant, Elaine Dzierzak, Martin Reijns,
@sproullab.bsky.social
and Andrew Jackson
edin.ac/4vDOCfM
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Rare ageing disorder links ‘biological clock’ to disease | Institute of Genetics and Cancer | Institute of Genetics and Cancer
Scientists have discovered a rare genetic condition which causes people to age at a much faster rate, offering fresh insights into the ageing process.
https://edin.ac/4vDOCfM
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What if DNA methylation changes aren’t just ticking of our biological clock but rather the rust breaking the gears? Very excited to share our work - how DNA methylation contributes to stem cell dysfunction and aging, published in
@natgenet.nature.com
doi.org/10.1038/s415...
#epigenetics
#aging
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A progeria syndrome links DNA hypermethylation to age-related pathology - Nature Genetics
This study investigates the consequences of hypermethylation in a progeria syndrome caused by gain-of-function DNMT3A mutations, finding effects on adult stem cell function.
https://doi.org/10.1038/s41588-026-02633-8
about 1 month ago
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reposted by
Dan Sarni
Duncan Sproul
over 1 year ago
We've been awarded a UKRI MRC grant to examine the causes and consequences of
#heterochromatin
hypomethylation in cancer 🥳.
#postdoc
opportunity coming in the near future.
#epigenetics
. Please share with anyone who might be interested.
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