How liquid-like is the nuclear pore barrier?🍝𖣐 Our new preprint shows that FG-NUPs exhibit nanosecond-scale, liquid-like mobility in living cells. 💧⚡O-GlcNAcylation and an importin-β gradient keep the FG network liquid-like, reconciling nuclear pore complex models.

IDPSeminars is back again! Join us this Thursday at 1 pm Central (US) / 7 pm EU time! idpseminars.com

Exciting news 🎉 Edward Lemke has been elected as a member of the Academia Europaea! More information can be found here: www.ae-info.org/ae/Acad_Main... @acad-euro.bsky.social

🚨New Review Alert!🚨How do disordered FG-Nups regulate nuclear transport?🍝🐍 Our latest review explores recent advances in imaging & modeling, linking NPC function to disease. #NuclearPore #FGNups #Biophysics 👉 portlandpress.com/biochemsoctr...

Back in Germany and reunited with my former colleagues from the @lemkelab.bsky.social over a wonderful dinner. It truly feels like coming home!❤️

Novel analysis of intrinsically disordered proteins🐍📏

Happy Chinese New Year from our lab! 🧧✨ Just as we unravel the mysteries of intrinsically disordered proteins, may the Year of the Snake bring clarity to complexity and spark breakthroughs in our scientific journey. Wishing everyone a year filled with innovation, discovery, and success! 🐍🔬

In the cover story of the February issue of @sciam.bsky.social I explain what biomolecular condensates are and why they are transforming cell biology. A short 🧵 (You'll need a subscription to read the article.) www.scientificamerican.com/article/myst...

In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:

Reliable analysis of #IntrinsicallyDisorderedProteins: Researchers of #MainzUniversity and @embl.org Hamburg present new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample 👉 press.uni-mainz.de/reliable-ana... @imbmainz.bsky.social

Thrilled to share our latest paper in PNAS! We enhanced SAXS with noncanonical amino acid labels to extract both RG and RE of IDPs, addressing key discrepancies in biophysical measurements. Big thanks to Lemke Lab for the amazing ASAXS-inspired T-shirt! www.pnas.org/doi/10.1073/...