In certain fields, manuscript submissions are way up due to researchers using AI to help do data analysis and writing.

PSA: the next online Ekkolapto salon will feature a discussion with Jim O'Shaughnessy & Atman Pandya on new mechanisms for science funding. RSVP here to join the Zoom call: luma.com/oshaughnessy...

PSA for Boston-area folks - special event Monday Nov 10th on the future of AI and humanity. RSVP Here: www.aicamp.ai/event/eventd...

PSA: tomorrow afternoon (Oct 30th) ekkolapto is hosting an online (Zoom) Salon w/ Niko McCarty from AsimovPress, a one-of-a-kind magazine about scientific progress in biology. Should be really interesting and a great chance to ask Q's to Niko! RSVP here luma.com/asimovpress?...

Mind First Foundation Chief Scientist Preston Estep has published a review of "If Anyone Builds it Everyone Dies". A key point is that we need more rigorous scientific study of Steve Omohundro's emergent AI drives! Furthermore, AI scientists may help us craft safe AI. s-rsa.com/index.php/ag...

'Wrong to weigh in': GOP senator condemns FCC chair's 'absolutely inappropriate' move

Today, 9/21/2025, at 1 p.m. Pacific Time, the U.S. Transhumanist Party invites Professor Stefan Lorenz Sorgner to discuss Euro-Transhumanism, a vision that emphasizes a culturally nuanced, ethical, and inclusive approach to technological enhancement. www.youtube.com/watch?v=MJUA...

5,290 papers at #NeurIPS this year, out of ~23,000 submissions.

Trump is starting to ramp up an unprecedented assault on the First Amendment. Everyone should be paying attention to what's happening right now, and be ready to speak up for your rights!

An absurdly comprehensive treatment of the (relatively negligible) effects AI has on the environment.

Not a good look... 😬 (www.thefp.com/p/students-c...)

👇

Updated Novavax vaccine for #COVID dropping soon! ir.novavax.com/press-releas...

Great news today from Jim O'Neill, ChatGPT is available to all workers at HHS!

Great example of the Streisand effect 😆🤣

🤦‍♂️ And the worst part is all the taxpayer $ being wasted on a lot of these sites...

Bill and Liz have some great ideas on a new approval pathway at the FDA! You can join the YouTube livestream today (Sunday, August 17) from 4 - 6 pm ET and ask questions in the chat => www.youtube.com/watch?v=t9px...

PSA for Boston-area folks!! The 𝙷𝚞𝚖𝚊𝚗 𝙰𝚞𝚐𝚖𝚎𝚗𝚝𝚊𝚝𝚒𝚘𝚗 𝚂𝚞𝚖𝚖𝚒𝚝 will be held at the MIT Media Lab on August 23rd. Come see the products & projects that are pushing intelligence augmentation, bio-interfaces, longevity, consciousness, and more! I’ll be attending along w/ a bunch of @Ekkolapto folks!!

🚨🚨Parts of the Constitution were just casually deleted from Congress's official Constitution website. 😬 The parts deleted involve habeas corpus rights, forbidding titles of nobility, & forbidding foreign emoluments (salaries/gifts) for US officials. See for yourself: web.archive.org/web/diff/202...

Clearest evidence yet Trump is a wannabe dictator with no comprehension of or respect for the Constitution. Unfortunately, I suspect many ppl aren't aware of what's going on since people have been screaming "fascist!", etc for about nine years over every little thing, which causes ppl to tune out..

New on my Substack. If you find value in my posts, consider subscribing. You can also give a one-time donation here: coff.ee/moreisdiffer.... I am thinking of quitting my job to focus on writing full-time for a period. open.substack.com/pub/moreisdi...

Periodic reminder of this article by @jacobtref.bsky.social: blog.jacobtrefethen.com/10-technolog...

Meanwhile in the UK - government goons are bragging about how they are arresting people for non-violent, non-threatening speech. It's terrible what’s been happening in the land of John Stuart Mill.

Election denialism and tin foil hat conspiracy theories exist on the left too - this viral Substack post alleges that Elon Musk used Starlink to manipulate voting machines, LOL, together with Palantir. Also, Trip Lite UPS machines had "backdoors" and were network integrated with voting machines..

This story broke a month ago, but I just learned a few days ago and decided to write a post about it! moreisdifferent.blog/p/that-mit-p...

PSA - July 31st is the deadline for the Norm Handy Prize and Foresight Fellowship program at the Foresight Institute! foresight.org/norm-hardy-p... foresight.org/foresight-fe...

The amount of land the federal government owns is mind boggling. We should be selling small bits of land that have extremely high values for home building, like barren desert outside of Las Vegas (pictured below). Read Alex Tabarrok's latest : marginalrevolution.com/marginalrevo...

PSA: The American Science Acceleration Project has a request for information (RFI), and the deadline is tomorrow! Their goal is to make science 10x faster by 2030. This is admin is unusually friendly to metascience, so your comments could go a long way! www.rounds.senate.gov/imo/media/do...

Alex Kesin has presented a set of arguments for making statins available OTC Statins have been proven to be much safer than many of today's OTC drugs. Only 35% of ppl eligible under current guidelines are taking them. Alex estimates the cost per QALY is less than cost of a fast food combo meal 🤯🧵⬇️

wow, the Endnote plugin doesn't really work at all

I bet this tweet is why it's happening. Alcatraz was originally closed because it was three times more expensive to run.

Just published some thoughts on #LongCOVID research => moreisdifferent.blog/p/why-are-we...

Great quote

yikes Read economist Alex Tabarrok speaking out about these harmful layoffs at the FDA: marginalrevolution.com/marginalrevo...

I'm recovering from fatigue from flu (5 weeks ago) & a minor cold (3 days ago), and I'm tapering off wellbutrin. I've been noticing depressive thoughts. Interestingly, it seems like my perception of world is more accurate? I'm seeing a lot of flaws & limitations w people & things..#DepressiveRealism

83 hours of audio for $14.99. Great for falling asleep quickly -- your brain will tire fast trying to follow his prose style. Written around 100 AD... The biographies of Cicero and Alexander are very interesting! www.audible.com/pd/Parallel-...

Clever poster I spotted at the Rally for Science: "Know Science, Know Progress. No Science, No Progress"

It's true! Join us, the water is warm and the people are friendly, thoughtful, truth-seeking, and charitable. substack.com/notes

Two events tomorrow in DC... who's going ? standupforscience2025.org/dc-rally/ www.facebook.com/events/17415... #StandForScience #PEPFAR

We have a new publication in JACR! We ran AI segmentation tools to automatically extract CT biomarkers from the CT scans of 899 patients who were stuck on kidney transplant waiting lists. We investigate mortality risk prediction... artice: www.jacr.org/article/S154... PDF avail on my website.

lol, the irony

I wrote an article over the weekend on Microsoft's new "breakthough" quantum chip. I go into detail regarding the physics & the troubling history of similar claims - 2 topics I haven't seen covered in much depth elsewhere. I conclude w/ some metascientific notes. moreisdifferent.blog/p/a-critical...

I heard plaid shirts are not good for dating, so I ferreted away all my plaid shirts into a closet. What do people think? The sentiment seems right - solid shirts have a more edginess to them, while plaid has more "I'm already taken and settled" vibes.

Wow: "When we last did some estimates, we were getting numbers that place greening Mars in the department of $100B’s and ~30-50 years...roughly the cost of the US’s interstate highway system. Of course, the biggest problem with these estimates right now is that not enough ppl are thinking about it."

A tour de force book. Hopefully this will inspire more people to be forensic metascientists and also funders to come forward to fund this much-needed work. #metascience

I just stumbled across the best wastewater monitoring dashboard. It allows to view GRAPHS. (not just meaningless "high", "low", etc on the CDC's one). Covers COVID, RSV, Influenza and 2 others I've never even heard of, all on the same dashboard.. @wastewaterscan.bsky.social data.wastewaterscan.org

Today is the last day to submit a proposal for the #Metascience2025 conference. They way they describe it, it almost sounds more like a "meta-metascience" conference.. metascience.info/call-for-pro...

Interesting..

Cutting employees from the FDA would be a terrible idea, although there probably is some “dead weight” that could be tossed. They need more employees and higher salaries, especially in areas like emerging tech. Unfortunately RFK Jr seems mostly bent on some sort of crazy “burn it down” strategy..

Treasury Secretary Bessent pushes back against misinformation and disinformation about DOGE: www.youtube.com/watch?v=8EHe...