Jessica Lehoczky
@lehoczky-lab.bsky.social
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Regenerative medicine/developmental biology/mouse genetics; Harvard Medical School/BWH Orthopedics
It’s finally out!! Congrats
@vivijou.bsky.social
www.science.org/doi/10.1126/...
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Mouse digit AAV gene delivery into fibroblasts regulates regenerative outcome
AAV delivery of putative proregenerative genes into proximal, nonregenerative mouse digit fibroblasts induces regeneration.
https://www.science.org/doi/10.1126/sciadv.adz0229
10 days ago
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Congratulations to Vivian who is now officially Dr. Jou!!!
@vivijou.bsky.social
Check out our newest preprint showcasing the AAV delivery technique Vivian developed for the mouse digit. Spoiler alert: she shows AAV delivery of single candidate genes can modulate fibrosis and regeneration!
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Mouse digit AAV gene delivery into fibroblasts regulates regenerative outcome
The distal mouse digit tip regenerates post-amputation, while the proximal digit undergoes fibrosis. This study presents a comparative single-cell RNA sequencing-based analysis of regenerating and non...
https://www.biorxiv.org/content/10.1101/2025.04.22.650049v1
9 months ago
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reposted by
Jessica Lehoczky
Igor Schneider
10 months ago
Our preprint is out! Kudos to
@josanesousa.bsky.social
,
@gabrielalima19.bsky.social
,
@perezlouise.bsky.social
and undergraduate prodigy Hannah Shof! By comparing Polypterus fin and axolotl limb we find shared and new regeneration programs.
@lsuscience.bsky.social
www.biorxiv.org/content/10.1...
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reposted by
Jessica Lehoczky
Michalis Averof
11 months ago
Do you have experience in generating transgenic tools and fluorescent markers? Are you interested in developing new tools in a non-conventional model, to observe and genetically manipulate cells during leg regeneration? We are recruiting!
www.averof-lab.org/pages/3560
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reposted by
Jessica Lehoczky
International Society for Regenerative Biology
about 1 year ago
Interested in regeneration? Consider joining the ISRB community! Details below.
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