half way through an article about life and consciousness from Harpers and realized that I must write for myself…

Trying to understand how to stay grounded when knowledge behaves like a living thing. Four early-modern voices—More, Montaigne, Bruno, Ibn Khaldun—turned out to have surprisingly current lessons.

much love to everybody

A paper in Nature Biotechnology presents CellWhisperer, which uses multimodal learning of transcriptomes and text to answer questions about single-cell RNA-sequencing data. go.nature.com/3XqzItR 🧬 🧪

favorite movies Friend asked if Constantine was my favourite movie… I mean Neo and the librarian in one movie?? Yes please! but… Not my favorite though… that would be between Notting Hill, The Mummy, and The Matrix. None of them are good movies — in the way that Perfect Days and sooo many others…

Rhyme, collected RhymeManaged memory leaks.EverythingNeatly tucked away. The poets freedBy print. Hackers Tamed themselves.Linting,Hinting, diff-printing Bolt cutters:vibe- image: Rain, Steam and Speed

and it works! they made a tiny 8B model that holds up well against many large MoE models

was away, what did i miss? (i'm aware of the politics). Give me tech, stats, AI, Bio... My brain is so hungry

Hey, wanna try something with me? This is an editable document. Add to the story. Share the link so others can contribute leaflet.pub/aefd4342-396...

I mean if @gracekind.net says so, I must be

Reddit opinions on Hollow Knight 10 years ago #indiedev

Johnson, Adayshia (2022). “Ibn Khaldun’s Views on Race: Influences by Early Life/Childhood, Climate, Geography, and Geographic Segmentation.” The Macksey Journal: Volume 3, Article 95. #HistSTM #HistSci #Sociology mackseyjournal.scholasticahq.com/article/5565...

To remedy this I have gone from simple quoting to drug hunting

A shout out for @nrennie.bsky.social fab book on data viz! nrennie.rbind.io/art-of-viz/

I just wanna say I was playing Qud before all this award brouhaha. Congrats to everyone!!

Zen or RDF?

Before COVID we didn’t even know a virus causes multiple sclerosis. They just figured out how it does it. www.nature.com/articles/s41...

Dunno why people trying @leaflet.pub gets me excited. But it does!

The coolest bit (as much as I understand it) is that a nucleus-free ova is a niche big enough to be a stage for this genetic drama

h/t @scientificdiscovery.dev for pointing me to this book

NEW EPISODE of HARD DRUGS! “5 hours is too long!” some of you said after our first episode. So our second episode is 20 minutes 🤭 @jacobtref.bsky.social and I explore the world of proteins: how proteins fold into complex shapes, why complexity matters, how crowded and dynamic a cell really is.

I've noticed several great ~linkblogs~ on @leaflet.pub lately — here's a lil thread! oh and btw for my linkblog friends & similar collection-makers etc. using Leaflet — we just added iframe embeds! for a bunch of these, particularly useful for nice YouTube video display…but plz test others too!

The only kind of article writing I want

"wait so you're making an app that's part gdocs/notion & part substack/wordpress & built on atproto & fully open source & I can login w/ bsky & own my data & theme my pubs & add custom domains & there's a whole block editor & it's just three of you making it & also it's free?" yes that's correct :)

my uncle just called someone "li-curious" (linux curious) lmao

The way it should be. Bokeh bokeh! 😍

It can also be self-hosted if the need arises

"Pat, why do you carry that ridiculous 600mm lens on long hikes?" Buddy, I can see mountains reflected in the eyes of a trailside pika.

Exactly!!

Part of Summer of Protocols again this year

@leaflet.pub is such an innovative platform If you select some text (1), a tooltip appears that allows you to share the selection as a quote on Bluesky (2) If you click the Quotes icon (3), a panel showing all quotes appears (4) It's a terrific integration between blogging and microblogging