🆕 Letter in JCMC: @EuroSIVA urges action on TCI pump PK/PD model errors ⚠️ 🔑 Key points: • Implementation mistakes can cause dosing discrepancies • Need for formal testing & regulatory oversight • One model–one drug for safer TIVA link.springer.com/article/10.1...

📣 Big news! JCMC will be fully Open Access from Jan 1, 2026 🗓️ 📌 All submissions after Sep 2, 2025 will have an APC (waivers available) 🔗 FAQs : link.springer.com/journal/1087... ✅ Tech in anesthesia, ICU, ER & peri-op medicine ✅ Rigorous peer review ✅ Expert editorial guidance

🫀👶renal and cerebral tissue oxygen saturation & AKI 🔎 49 kids, CPB surgery 📉 SrO₂ & ScO₂ drops ❌ not linked to AKI ⚠️ AKI (18.4%) linked to ↑ creatinine, ↑ BMI, intraop hypotension & ↑ lactate 📊 NIRS may not predict AKI in this setting link.springer.com/article/10.1...

“Everything is there to work safely, we don’t need anything. There’s no excuse for going in the OR and make the job OK." 🎙️ The interview with Thomas Fuchs-Buder is finally out on YouTube, Spotify and all podcasting platforms! www.youtube.com/watch?v=ocAb... open.spotify.com/episode/3hV7...

💧 Thoracic fluid content (TFC) & bioimpedance in ICU 👥 42 patients (fluid bolus) + 23 ARDS patients 📈 TFC rose after fluids but ❌ not correlated with GEDVI or CVP ❌ No link between TFC changes & EVLWI ➡️ TFC not reliable for preload/EVLW tracking link.springer.com/article/10.1...

👁️pupillary unrest as OIRD marker link.springer.com/article/10.1... 🧪 10 adults (40–60y) + 20 younger controls, remifentanil infusion (0.2–0.3 µg/kg/min) 📉 PUAL declined during infusion, rose in recovery 📊 AUROC 0.98 → strong discrimination of high-risk opioid exposure, consistent across ages

🚨 64 TAVI pts (mean age 82): AKI in 33%. 🚫 No link between renal rSO₂ changes (time-weighted, Δ, nadir) and AKI. ✅ Renal NIRS not predictive of post-TAVI AKI → better tools needed for early detection/prevention link.springer.com/article/10.1...

🧒🧠 SEF95 in pediatric anesthesia: BIS® vs SedLine® compared in 51 kids (402 paired values). 📊 r²=0.73, bias 0.62 Hz, LoA −4.08 to 5.32 Hz. ⚖️ Differences up to ±4 Hz, closer during maintenance. 👉 Further studies needed on clinical impact link.springer.com/article/10.1...

💧 PVI-guided fluid therapy in non-cardiac surgery vs conventional care: 📉 Fluid −761 mL, crystalloids −655 mL ⚖️ No change in BP, urine, LOS ✅ Restrictive, individualized, non-invasive option for periop fluid optimization link.springer.com/article/10.1...

📢 ICU alarms often overwhelm staff due to false alerts 🧒 Age-specific thresholds cut alarms by: 💓 ECGHR ↓31% 🌬️ ECGRR ↓18% 🩸 SpO2 ↓55% ⏱️ 15s delay ↓ alarms by 45% link.springer.com/article/10.1...

📊 A meta-analysis of 36 studies (1,888 pts) >> pulsed co-oximetry closely matches invasive hemoglobin measurements (MD: 0.13 g/dL, NS). Reliable, non-invasive, and continuous—supporting its perioperative use to guide perioperative transfusions link.springer.com/article/10.1...

⚠️ A flaw in the Eleveld model implementation in a TCI pump was found: obese patients received underdosed propofol due to incorrect weight adjustment 🟢Value of Simulation Tools 🟢Need for Rigorous Certification 🟢Importance of Reporting Platforms link.springer.com/article/10.1...

🧪 RCT in trauma patients: ORi monitoring vs. pulse oximetry to guide FiO₂. 📉 ORi group had more normoxemia (64.4% vs. 40.4%, p=0.002) 📊 ORi correlated with PaO₂ ✅ ORi use reduced intraop hyperoxemia safely 🌬️ Smarter O₂ titration with ORi! link.springer.com/article/10.1...

In 697 noncardiac surgeries from EU HYPROTECT: ⚠️ 9% developed AKI 📉 Time under MAP <65 mmHg independently predicted AKI 🧮 OR 1.03 per 10 mmHg·min (P<0.001) 📢 Even when carefully avoided, hypotension = AKI risk link.springer.com/article/10.1...

🫁🛏️ Weaning from mechanical ventilation: 📊 DE-RSBI (≥1.685) had best accuracy (AUC=0.851) ⚠️ Odds of failure: 🔺 DE-RSBI >1.56 ➡ OR=12 🔺 DTF-RSBI >62.3 ➡ OR=8.04 📉 RSBI alone ➡ OR=4.84 ✅ Ultrasound-derived indices improve weaning prediction! link.springer.com/article/10.1...

🧒📉 esCCO for cardiac index in ventilated children showed poor accuracy vs TTE at baseline (bias +5.9, error 106.9%) ✅ After TTE-based recalibration, accuracy improved at 2h (error 12.7%) & 18h (error 20.7%) 🔁 Regular recalibration needed link.springer.com/article/10.1...

🫁 New method to set optimal PEEP using barometric capnography (BCap) 📉 👥 11 pts 🔬 BCap PEEP matched standard compliance-based PEEP (p=0.72) 📊 Strong correlation with PEEPPL (Rho=0.93) ✅ BCap is a feasible tool to detect lung collapse link.springer.com/article/10.1...

👶📈 Monitoring newborns in the NICU is evolving! 🆕 Tech: PPG, wireless sensors, spectroscopy & tremolo sonification 🔍 Detect HR/O₂ sat changes early 🧠 Smart models & closed-loop systems aid decision-making ⚠️ Next step: integrate into clinical care! link.springer.com/article/10.1...

🔬📍 Distal radial artery (DRA) vs conventional radial artery (CRA) catheterization ✅ Similar final success & safety ⏱️ DRA = faster hemostasis 🚫 DRA = lower 1st-attempt success (comparable if US was used) link.springer.com/article/10.1...

🎯 Automating anesthesia mode switches by predicting surgery start from OR staff actions via video analysis 🎥 110 OR videos analyzed 👨‍⚕️ 5 key actions tracked 🧼 Hand washing 🧴 Sterilization 💡 Light activation 🛏️ Bed cradle set-up 🟦 Draping link.springer.com/article/10.1... 🧵👇

📢 New #ImpactFactor alert! 📰 JCMC rises from 2.0 → 2.2 in 2024 🔼 📊 Ranked 26/68 in Anesthesiology (Q2 – Clarivate) Thanks to all authors, reviewers & editors who support the journal’s progress

🔍 Renal Doppler & AKI Prediction 👥 80 ICU patients ,acute circulatory failure 🔄 ΔRRI/PDU & ΔPDU stronger in AKI ✅ Renal Doppler (RRI, PDU, RRI/PDU) can help early AKI prediction in critically ill adults link.springer.com/article/10.1...

🧠The second episode of the new season is out!!! 📢 🎙️This time we’re interviewing Prof. Matthias Kreuzer — a VIP in the world of EEG and anesthesia! 💚https://open.spotify.com/episode/37IZnm1luxZhKkkyPXmX7Z?si=UD3T8PFmQ_mrk5N5bL4Tuw ♥️https://youtu.be/2WBH0JLEsv0?si=uDnBILPh-B351GTK

💡 10 pts: supine vs lateral during anterolateral THA 🧠 MEPs monitored at 4 stages 📉 Supine → lower MEPs (p < 0.05) 🤕 No postop paralysis ✅ Lateral position may better protect femoral nerve function link.springer.com/article/10.1...

💉 Anesthesia & 😖 pain confound HRV signals. 🧠 pEEG & NOL 🧪 can help contextualize HRV data. 📊 Integrating depth of anesthesia & nociception monitoring may improve HRV interpretation in critical care an editorial by A Gentile and @michele-introna.bsky.social link.springer.com/article/10.1...

🧪 RCT on HPI-Guided Management During Prone Spine Surgery link.springer.com/article/10.1... 📌 Key Findings: 🧵 👇

🧠💉 Does Quantitative NMT need calibration? TOF precision was best when EMG calibration was done before induction (📉 repeatability: 0.075), nearly matching gold standard Uncalibrated = least precise (0.124). No pain differences at induction. ✅ link.springer.com/article/10.1...

🫁 During GI endoscopy >> capnography vs pulse oximetry alone: ✔️ Detected apnoea <60s (35.4% vs 0%) ✔️ Reduced moderate hypoxaemia (3% vs 6.5%) ✔️ Lowered severe hypoxaemia in high-risk pts (2.2% vs 4.4%) Fewer ❤️ events 😊 Higher patient satisfaction link.springer.com/article/10.1...

Interesting, but how to compare with this - is there really a fixed LLA? pubmed.ncbi.nlm.nih.gov/29339351/

🧠 In infants ≤3 months, ML + qEEG predicted sevoflurane levels (% expired) with ~68% accuracy across 4 ranges. 📊 Top features: burst suppression ratio & β-entropy 🧪 Data: 4574 EEG epochs from 42 infants 💡 Supports future infant-specific EEG tools link.springer.com/article/10.1...

🩺 Improving urinary oxygen monitoring with a transit time algorithm @utah.edu link.springer.com/article/10.1... 🔁 A new algorithm correcting for flow delay cut RMSE from 15.7 → 5.8 mmHg. ✅ More accurate, noninvasive monitoring of kidney oxygenation

ANI vs. SPI abd lps surgery 👥 40 pts 💉 propofol, keta, remi 🎯 remi titrated to ANI 50–80 📉 ANI: •70 ➡️ 57 at intub •50–80 📈 SPI: •60 ➡️ 38 at intub •73 at extubation •20–50 📊 Correlation ANI/SPI: weak (r² = 0.053, p < 0.001) link.springer.com/article/10.1...

🕊️The JCMC editorial board joins in mourning the loss of Rinaldo Bellomo. Rest in peace 🖤

🧠💉 In ❤️ surgery, raising CPB flow (2.2 ➡️ 2.8 L/min/m²) didn’t ⬇️ the lower limit of cerebral autoregulation (LLA) link.springer.com/article/10.1... 📊 LLA delta: –2.8 mmHg (p = 0.25) 🧪 24% had LLA < 65 mmHg at conventional flow vs 35% at high flow 🧠 Autoregulation stable

🫀📉 Heart rate variability (HRV) may help track MODS severity in ICU patients @univlille.bsky.social link.springer.com/article/10.1... 📚 10 studies (2004–2024): ↓ HRV seen in MODS & non-survivors HRV linked to MODS severity & mortality risk ⚠️ Results depend on patient traits & HRV methods

🔦 Ambient light affects pupillometry in ICU patients. link.springer.com/article/10.1... 🧪 In 20 ventilated adults: NPi was lower in bright vs. dark conditions 25% showed ≥0.6 drop in NPi with light No NPi change between repeated dark tests ⚠️ Light level should be considered in QP interpretation

📱 SMART-QT app was validated to semi-automatically measure QT/QTc from ECG snapshots link.springer.com/article/10.1... by D Beckmann @berndsaugel.bsky.social 🇩🇪 🧪 Compared to manual ECG: • QT diff: 14 ± 20 ms • QTc diff: 13 ± 15 ms ✔️ Clinically acceptable accuracy