Ankur Gupta-Wright
@ankurgw.bsky.social
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Infectious Diseases Consultant and Academic TB, HIV, respiratory infections, AMR, diagnostics
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Ankur Gupta-Wright
BreathForDx
3 months ago
🎥 The first BreathForDx webinar is now online! We discuss community engagement and early steps in breath-based diagnostics for infectious diseases. 👉 Watch it here:
breathfordx.org/project-reso...
#BreathForDx
#GlobalHealth
#Diagnostics
#EUresearch
#Webinar
#CommunityEngagement
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Project webinar - Breath For DX
PROJECT RESOURCES
https://breathfordx.org/project-resources/project-webinar/
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Ankur Gupta-Wright
Imperial Medicine
2 months ago
Prof Lord Ara Darzi, writing in
@observeruk.bsky.social
, warns that axing the Fleming Fund, Britain’s landmark antimicrobial resistance initiative (
#AMR
), would be a deadly retreat. With 5 million annual global deaths, the stakes couldn’t be higher.
observer.co.uk/news/nationa...
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‘Bacteria knows no borders. The UK and Fleming Fund must ...
The planned dismantling of the world’s largest fund to fight antimicrobial resistance could contribute to millions of deaths worldwide
https://observer.co.uk/news/national/article/bacteria-knows-no-borders-the-uk-and-fleming-fund-must-stay-in-the-fight
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Ankur Gupta-Wright
BreathForDx
3 months ago
🌬️ Discover the Power of Breath in Diagnostics! Over the past months, we’ve been working across Europe and South Africa to develop breath-based tools for diagnosing respiratory infections — and now you can see what we’ve been up to. 📺 Watch the full video here: 👉
breathfordx.org/project-reso...
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Project video - Breath For DX
PROJECT RESOURCES
https://breathfordx.org/project-resources-2/project-video/
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Despite molecular diagnostics for TB, 40% of patients are still diagnosed clinically. We also found a 50% higher mortality in this group, suggesting overtreatment/missing conditions other than TB.
www.sciencedirect.com/science/arti...
@imperialinfect.bsky.social
@uniheidelberg.bsky.social
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Clinically diagnosed tuberculosis and mortality in high burden settings: a systematic review and meta-analysis
Clinical diagnosis of tuberculosis (TB), referring to diagnosis without bacteriological confirmation, is common and may affect an individuals’ outcome…
https://www.sciencedirect.com/science/article/pii/S258953702500183X
4 months ago
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Excited to be presenting an outline of our
@ec.europa.eu
funded B-Path programme to advance breath-based diagnostics for respiratory infections at PREPARE-EU
@uniheidelberg.bsky.social
@cdenki.bsky.social
@digbywarner.bsky.social
add a skeleton here at some point
5 months ago
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Ankur Gupta-Wright
BreathForDx
5 months ago
BreathForDx is a EU-funded research initiative aimed at improving early diagnosis of respiratory infections through exhaled breath aerosol (XBA) sampling. It combines non-invasive diagnostic innovation with clinical research to detect tuberculosis and viral infections.
breathfordx.org
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Breath For DX - Making every breath count for diagnosis
Making every breath count for diagnosis. Establishing Exhaled Breath Aerosol (XBA) sampling for diagnosis and screening of respiratory infections.
https://breathfordx.org/
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Ankur Gupta-Wright
Clinical Infectious Diseases
6 months ago
Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial
#IDSky
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Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial
People with human immunodeficiency virus (PHIV) admitted to the hospital have high mortality, with tuberculosis (TB) being the major cause of death. Systematic use of new TB diagnostics could improve TB diagnosis and might improve outcomes.
https://doi.org/10.1093/cid/ciae273?utm_source=bluesky&utm_medium=organic-social&utm_content=%40cidjournal.bsky.social&utm_campaign=CID-Article-Promotion
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Great to see utility of rapid TB dx being demonstrated
tinyurl.com/jvfka44d
. Graet to be part of ongoing development of dx for drug resistant TB with R2D2 TB Network
@cdenki.bsky.social
and teams in Georgia/Philippines/SA.
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Programmatic Diagnostic Accuracy and Clinical Utility of Xpert MTB/XDR in Patients With Rifampicin-Resistant Tuberculosis in Georgia
AbstractBackground. Xpert MTB/XDR (Cepheid) is recommended by the World Health Organization for drug susceptibility testing in patients with tuberculosis,
https://tinyurl.com/jvfka44d
7 months ago
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Ankur Gupta-Wright
Peter MacPherson
10 months ago
How Glasgow's 1957
#tuberculosis
screening programme could help countries today.
#episky
#IDsky
🛟🧪🦠
www.thelancet.com/journals/lan...
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How Glasgow's 1957 tuberculosis screening programme could help countries today
Visitors arriving in Glasgow, UK, today are met with a city that's undergone massive regeneration, from the colourfully illuminated exterior of the Hydro music venue on the old dockside along the River Clyde, to the stratified medicine cluster that is growing up around the Queen Elizabeth University Hospital, one of the largest facilities in Europe. Wind the clock back to the 1950s, and visitors were faced with a city shrouded in smog from factories and coal fires, full of many people living in substandard, overcrowded housing, and suffering from poor nutrition, with World War 2 rationing only ending in 1954.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00406-5/fulltext
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reposted by
Ankur Gupta-Wright
Madhu Pai, MD, PhD
10 months ago
Tuberculosis: a biosocial problem that requires biosocial solutions
www.thelancet.com/journals/lan...
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Time to stop funding/doing more vit D in TB trials?
add a skeleton here at some point
10 months ago
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Ankur Gupta-Wright
Antibiotic Steward 🅱️C🆔🅿️🌟
10 months ago
Are Bacteria Sensitive or Susceptible? A Micro-Comic Strip 😂 S: Susceptibile or Sensitive ? Which one you use? Me : Susceptible
#idsky
#microsky
#medsky
journals.asm.org/doi/10.1128/...
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Ankur Gupta-Wright
The Guardian
10 months ago
Footprints in Kenya ‘show distant relatives of modern humans coexisted’
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Footprints in Kenya ‘show distant relatives of modern humans coexisted’
Researchers say fossilised marks were apparently made in same place within days of each other about 1.5m years ago About 1.5m years ago a big-toothed cousin of prehistoric humans walked quickly along a lakeside in Kenya, footprints marking the muddy…
https://www.theguardian.com/science/2024/nov/28/footprints-in-kenya-show-distant-relatives-of-modern-humans-coexisted?utm_source=dlvr.it&utm_medium=bluesky&CMP=bsky_gu
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reposted by
Ankur Gupta-Wright
Antibiotic Steward 🅱️C🆔🅿️🌟
10 months ago
A systematic review showed that there is still scant evidence to confidently confirm the benefit-risk of antibiotics use in preventing subsequent GAS
#idsky
#medsky
add a skeleton here at some point
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reposted by
Ankur Gupta-Wright
SHORTEN-2 trial
10 months ago
New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options? This meta-analysis of RCTs shows they are not superior to prior alternatives when available:
www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch
#AMSsky
#IDsky
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Effectiveness of novel β-lactams for Pseudomonas aeruginosa infection: A systematic review and meta-analysis
Novel β-lactams have in vitro activity against Pseudomonas aeruginosa (PA), but their clinical performances and the selection criteria for practical use are still not clear. We aimed to evaluate the e...
https://www.ajicjournal.org/article/S0196-6553(24)00104-4/abstract
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Ankur Gupta-Wright
Peter MacPherson
11 months ago
🚨New Publication🚨 led by
@biancasossen.bsky.social
In a 7 country study, we found that urine Xpert Ultra was as sensitive & more specific than AlereLAM for
#TB
diagnosis in people with
#HIV
Also predicts mortality and allows detection of Rif resistance.
authors.elsevier.com/sd/article/S...
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reposted by
Ankur Gupta-Wright
Antibiotic Steward 🅱️C🆔🅿️🌟
11 months ago
🔥Everyone's favorite
#shorterisbetter
table is updated🔥 "BALANCE is now published, so the table is now updated! GNB bacteremia is now listed as Bacteremia(non S.aureus) Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg
#idsky
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Ankur Gupta-Wright
Derek Cocker
11 months ago
Glad my first post on bsky is to highlight a review just out today by our group - discussing how digital health tech can optimise AMU. Let's ensure we build in equitable access and global solutions
www.thelancet.com/journals/lan...
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Using digital health technologies to optimise antimicrobial use globally
Digital health technology (DHT) describes tools and devices that generate or process health data. The application of DHTs could improve the diagnosis, treatment, and surveillance of bacterial infectio...
https://www.thelancet.com/journals/landig/article/PIIS2589-7500(24)00198-5/fulltext
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