Seahawks win a wild one to kick off Week 4.

This reaction.

The Steelers have ruled out LB Alex Highsmith (ankle), who has not yet practiced this week and will not travel to Dublin to play against the Vikings.

49ers coach Kyle Shanahan told KNBR that QB Brock Purdy is progressing towards returning to the field on Sunday:"I think (the toe) is feeling better each day and if that continues he should be good on Sunday."

Seahawks RB Zach Charbonnet, who is listed as questionable on the injury report, is expected to play tonight against the Cardinals. Charbonnet has been dealing with a foot injury, but was a full participant in practice on Wednesday.

49ers QB Brock Purdy is nearing a return. The Eagles will be without LB Nolan Smith for more than a month. Bucs WR Chris Godwin could play this week.

49ers GM John Lynch told KNBR that Nick Bosa will have his ACL reconstruction on Friday.

For TNF: -- Seahawks LB Boye Mafe is questionable, as is RB Zach Charbonnet -- though both fully participated. CB Devon Witherspoon is off the report. -- Cardinals OLs Paris Johnson, Will Hernandez and Evan Brown are all questionable, while WR Zay Jones was ruled out.

The move to start Jaxson Dart was not the surprising one, but the obvious one. Now the rookie gets to prove if he's the Giants' future and savior.

The Browns have signed OT Thayer Munford Jr. off the Patriots practice squad, and placed OT Dawand Jones on injured reserve, ending his season.

Terry McLaurin will receive another opinion on his quad today, and he's received several -- including from Dr. Williams Meyers, the nation's expert in core muscle injuries. As of now, they believe it's a quad injury. But more tests coming, as his status is in doubt for Sunday.

Still not over it.

Still alive. #LGM

Sources: The Texans are releasing S C. J. Gardner-Johnson. A surprise.

For those asking I bowled a 132. My all-time high.

Russell Wilson’s fourth down throwaway may have been it. It’s Dart’s time.

The Packers are signing OT Brant Banks to the 53-man roster from the practice squad, source said. A big move for the former UDFA.

The future is now: The Giants are making first-round rookie QB Jaxson Dart their starter, per me and Mike Garafolo. After just a short stint starting and an 0-3 record, Russell Wilson heads to the bench. The Giants had a package of plays for Dart. Now, they’ll unleash it all.

A significant development for the Titans: Coach Brian Callahan is handing off the play-calling duties to QBs coach Bo Hardegree.

The Bucs play the Eagles, Seahawks, and 49ers, and Mike Evans will likely miss the first two and potentially the third. Chris Godwin could return as soon as this week, which helps.

Bucs WR Mike Evans, who left Sunday’s dramatic win with a hamstring injury, had an MRI that revealed he’s out multiple weeks, per The Insiders. But it’s not as bad as last year when he missed four weeks. Solid news.

This earns Derrick Henry no fantasy points (unfortunately for me), but this is an awesome block to key the TD.

The Falcons have fired receivers coach Ike Hilliard and passing game coordinator T.J. Yates will assume those duties.

Coach Jonathan Gannon confirms that James Conner will have surgery and is done for the season.

Giants coach Brian Daboll, speaking to reporters, says of a possible QB change, “We’re evaluating everything.”

Happy Monday to all.

Tyquan Thornton has resurrected his career in KC. One acrobatic catch at a time.

Giants RB Tyrone Tracy Jr. (shoulder) has been downgraded to out.

Cardinals RB James Conner, who was carted off with his ankle immobilized, will need surgery to repair the injury he suffered today, sources say. He’s still undergoing tests to determine the full extent of the damage. But the respected Conner is out indefinitely.

49ers QB Mac Jones, who had dealing with a PCL sprain during training camp, told reporters that he reaggravated it today. Sounds like it affected his play. Good timing, with Brock Purdy nearing a return to the field.

49ers edge Nick Bosa is getting tests on his knee injury, coach Kyle Shanahan said. While the team does not believe it’s an ACL injury, they are checking everything.

Injury updates: — Cowboys WR CeeDee Lamb has been ruled out with an ankle injury. — Cardinals RB James Conner (ankle) was ruled out.

49ers DE Nick Bosa has been ruled out with a knee injury.

Chargers RB Najee Harris is being carted off with a non-contact lower-leg injury.

Welcome back, Carson Wentz.

The 49ers downgraded WR Jauan Jennings and QB Brock Purdy from questionable to out for today.

Actives/inactives: -- Browns OT Jack Conklin is out. -- Bucs WR Emeka Egbuka is active. -- Packers TE Tucker Kraft is active. -- Vikings LT Christian Darrisaw is active. -- Steelers DT Derrick Harmon is making his debut. -- Panthers WR Xavier Legette is out.

Chiefs WR Rashee Rice, suspended the first 6 games for violating the personal conduct policy, is allowed back in KC’s facility after this week, per terms of his suspension. While he can’t practice, Rice can participate in meetings and ramp up for a W7 return vs the Raiders.

49ers QB Adrian Martinez is expected to be the backup to Mac Jones today, source said. Makes sense to keep Brock Purdy out of harm's way for another week.

Bucs WR Emeka Egbuka (hip/groin) is listed as questionable, but he'll play with no limitations, source said. He missed two days this week.

Giants standout LT Andrew Thomas, who has yet to play this season while recovering from a Lisfranc injury, is planning to make his debut on Sunday, per me and Mike Garafolo. The team will be cautious, and Thomas will work out pregame to be sure. But the plan is to go.

Vikings LT Christian Darrisaw (knee) and S Harrison Smith (illness) -- both of whom have yet to play this season -- are expected to make their debuts on Sunday, sources say. Both are slated to start, but will likely rotate on and off.

Rams DE Braden Fiske, who is questionable with an oblique injury, will play against the Eagles, per me and Mike Garafolo.

Bears RB D’Andre Swift, dealing with a quad injury, will play on Sunday against the Cowboys, source said.

Seahawks WR Jaxon Smith-Njigba was added to the injury report as questionable because of an illness.

Denver Broncos are placing LB Dre Greenlaw on injured reserve Just a quad strain, so Greenlaw should be back at four games.

The Bears are placing star CB Jaylon Johnson on Injured Reserve because of a groin injury, source says. He’s out indefinitely.

Patriots CB Christian Gonzalez has been downgraded to out.

Colts CB Charvarius Ward Sr. has cleared the NFL’s concussion protocol and is off the injury report. TE Tyler Warren (toe) was questionable and now has been removed, as well. He will play.

49ers coach Kyle Shanahan says QB Brock Purdy is questionable for Sunday. He said Purdy made a "lot of progress" and said it's "highly unlikely" that he'll start. But could be a 2 or 3.