Excited to announce a new collaborative preprint about a structural concept 'local stability compensation'. This states structurally important motifs must be flanked by more stable helices. We observe this effect natural occurring RNAs and experimentally evaluate it. www.biorxiv.org/content/10.1...

It's great to see the latest RNA puzzles paper has come out. www.nature.com/articles/s41... Its a must-read for those interested in RNA structure prediction!

🧬 Excited to share our new preprint! DMS chemical mapping, a key technique for studying RNA structure. Everyone assumes low DMS reactivity = Watson-Crick , high = non-WC. However, analyzing 7,500 RNA structures containing known 3D structures reveals it's not that simple. doi.org/10.1101/2024...

I hope this place is more positive and science-friendly than Twitter. I look forward to chatting about awesome science.