Made it to 23 before it fell!

I NEED to tell you the story of Tae Heung “William” Kim. He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease. He's a *legal permanent resident* of the United States. And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.

If I had one request for today, it’s that people stop sucking at zipper merges.

The Pittsburgh bubble tea market is savagely competitive

For no reason at all

Took the boy to see a pioneer of autoradiotherapy.

This was a fun little paper with Rachel Bainbridge where we discovered that Xenopus laevis, a model organism in fertilization research, lacks the gene for PLCZ1, an enzyme previously thought to be essential for fertilization. 🧪 academic.oup.com/gbe/advance-...

Folks, get your kids cameras. Real ones, not some junk off Amazon. You can get a used Coolpix 100 or something similar for fifty bucks. Completely worth it.

Damn, dude was an all-timer

The omnipresence of the internet in our lives is bad, actually.

Ooh a phone call AND a message at 5:15 in the morning, what could it be?

I competed in a climbing competition. I didn't do well (143rd place) but I *did* do better than expected. Also, it was a lot of fun!

I did a few things too…

Wife did this one (from GBBO)

The kids’ effort this year.

I find it extremely strange that Microsoft VBA uses a non-monospaced font (that you can't apparently change?) in its editor.

🧪 Question for BlueSky science community. For false discovery analysis with gene expression data, I would use q-values (Storey-Tibshirani) to control for the large number of false positives derived from multiple hypothesis testing. But let's say you have copy number variation data?

Post a photo of yourself from a different era (before kids).

Got a great deal on dysentery carrots from Costco:

Post a picture you took (no description) to bring some zen to the timeline

Would it be too much to ask for those Yankee fans who assaulted Mookie Betts to face prosecution?

Pretty wild out there:

Kiddo is a natural at the crack

About to send

HRAS (Harvey) is named for a woman, Jenny Harvey. KRAS (Kirsten) is named for a man, Werner Kirsten. Anyways, TIL. 🧪

Wondering why I never met these guys at the block party patch.com/pennsylvania...

If you see this, quote-post with a beach from your gallery.

Happy kids back in school day for those who celebrate

If anyone knows anyone who might have gone to this event, please please please urge them to get in touch with the Colorado DPHE as soon as possible, ideally yesterday. They need shots and they need them *now*. Signal-boosting out to extra networks. 🧪🌱🦑🐠 coloradosun.com/2024/08/09/c...

Pittsburgh has an unusually high concentration of good bakeries

Boo

How can WebMD get away with writing things like this? “PLEKHA1. Also related to inflammation, this gene is on chromosome 10. Having it increases your risk of getting AMD. LOC387715. If you have this gene and you smoke, your risk of getting AMD goes up even more.”

I guess I’ve become sort of a science-hype debunker so as far as this goes, let me just say: it’s real. Really really real. You could soon get a shot every six months that would basically eliminate your chance of getting HIV. Taken a step further: we have the tools to eliminate HIV in our lifetime.

85% of all human clinical drug trials fail. The central fact of the biopharma industry, right there.

If you see this… post a photo you took at sunset (Castle Stalker, Scotland 2023)

Don’t know who needs to hear this but MSP is an absolute mess right now

Posted without comment

🧪Reviewer 2:

Freeport Beach, North East

Loathe as I am to admit it, but ENSEMBL numbering is much better than Refseq

www.post-gazette.com/local/city/2... One of the interesting things about having two work emails (one at UPMC, the other at Pitt) is that I heard from UPMC almost immediately after this happened and complete silence from Pitt so far.

Who can I blame for the fact that some gene names are used more than once (eg KAT1)? Human genes so fly people are off the hook.

Schenley Park Pittsburgh, PA