#HelloQuitteX #20Janvier

Delighted to share our last preprint!!! 🎉🎉🎉 biorxiv.org/content/10.1101/2024.12.11.627621v1 We share the first synthetic gene circuit guiding the self-organization of mammalian tissues in elongating structures by dynamically tuning growth, viscosity and adhesion.

An exciting result about controling signaling with density (doi.org/10.1038/s41467-024-53078-8) => As distal parts of rod-shaped aggregates are less dense., we get "free" spatial patterning in 3D! => Some interesting potential for feedback loops, if this circuit controls tissue physics...

I am thrilled to share that our work is finally published in Nature Communications!!! 🎉 🎉 🎉 I had the honor of leading the project to its finish line during my last years at USC, building on the groundbreaking work of my co-first authors Pranav Bhamidipati and Marco Santorelli. (1/n)