Clinical Gastroenterology and Hepatology
@aga-cgh.bsky.social
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📝 136
🌐In this nationwide cohort from Sweden, both histologic inflammation (vs. histologic remission) and clinically active IBD (vs. quiescent IBD) were associated with an increased 2-year mortality risk in patients with IBD. @jiangwei_sun; @ludvigsson 🔗:
https://ow.ly/QijX50YVzgj
2 days ago
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People with MASLD and advanced fibrosis have a substantial risk of hepatocellular carcinoma in this IPD meta-analysis. Findings may inform future risk‑stratification strategies. 🧬📊 @DrHuangDQ @LimRyan21 🔗:
https://ow.ly/rZKm50YVyPI
5 days ago
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🚨Placebo response rates are often high in patients with MASH, but vary by the outcome measured. This study offers critical insights to improve future clinical trial design. 🔗:
https://ow.ly/MymC50YVyEu
7 days ago
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Happening soon! Join us at AGA Central for You’ve Published Your Paper… Now What? and learn strategies for promoting your work from our @AGA_GHA & @AGA_CGH social media editors
Nikki Duong MD
and
Joseph Sleiman, MD
#DDW2026
📅 5/4 | ⏰ 2 PM CT | 📍 AGA Central
9 days ago
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Join us bright and early at AGA Central for our One Paper, Zero Confusion session — get tips on getting your title and graphical abstract just right from @AGA_CMGH editors-in-chief Michele Battle & Jonathan Katz!
#DDW2026
📅 5/4 | ⏰ 8 AM CT | 📍 AGA Central
10 days ago
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Happening today! Don’t miss our From Poster to Submission session at AGA Central with the editors-in-chief of @AGA_Gastro, @AGA_CGH, and @AGA_CMGH!
#DDW2026
📅 5/2 | ⏰ 1 PM CT | 📍 AGA Central
11 days ago
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Already published at #DDW2026? Join us at AGA Central for You’ve Published Your Paper… Now What? and learn what comes next. Featuring our @AGA_GHA & @AGA_CGH social media editors
Nikki Duong MD
and
Joseph Sleiman, MD
#DDW2026?
📅 5/4 | ⏰ 2 PM CT | 📍 AGA Central
12 days ago
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Mapping out your
#DDW2026
schedule? Join us at AGA Central for One Paper, Zero Confusion—tips on getting your title and graphical abstract just right with @AGA_CMGH editors-in-chief Michele Battle & Jonathan Katz! 📅 5/4 | ⏰ 8 AM CT | 📍 AGA Central
13 days ago
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Attending
#DDW2026?
Stop by AGA Central for our From Poster to Submission session! Featuring editors-in-chief of @AGA_Gastro, @AGA_CGH, and @AGA_CMGH. 📅 5/2 | ⏰ 1 PM CT | 📍 AGA Central
14 days ago
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📖 In case you missed it, the May 2026 issue of CGH is out! Featured topics ⬇️ 🟢 Esophageal inflammatory diseases 🟢 Extended risankizumab treatment in UC 🟢 CRC screening interventions ➡️ Full issue:
https://ow.ly/9shw50YRMt5
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14 days ago
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There's still time! The AGA Journals are accepting applications for a one-year editorial fellowship focused on editorial training and leadership development. ⭐Perfect for early-career GIs and PhDs ✅Applications due April 30, 11:50 p.m. EST 👩⚕️Learn more:
https://ow.ly/u7Gq50YOFoY
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20 days ago
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💊GLP-1 drugs like Ozempic and Wegovy have far-reaching health benefits beyond weight loss. In a new nationwide cohort study, researchers from Beth Israel Deaconess Medical Center are adding one more to that list: prevention of ulcers in the gut. 🔗:
https://ow.ly/u2Oa50YO61B
21 days ago
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🌟This international, multicenter study identified both commonalities and unique differences in disease phenotype and behavior by geography and immigrant status, highlighting the impact of changing environment on CD phenotypic expression. 🔗:
https://ow.ly/A8uK50YLl9u
26 days ago
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Subcutaneous infliximab (infliximab‑dyyb SC) maintenance improved outcomes in Crohn’s disease regardless of location, showing consistent efficacy across ileocolonic segments—including the terminal ileum. 💉✨ 🔗:
https://ow.ly/PuPX50YFESt
28 days ago
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🥗 Do dietary emulsifiers affect gut health? In a randomized trial, an emulsifier‑free diet lowered cholesterol, while common emulsifiers reduced short‑chain fatty acids and increased gut permeability in some participants. 🧫🦠 🔗:
https://ow.ly/pVeC50YFEq4
30 days ago
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📈 DGBI prevalence and burden increased in the UK & US after COVID-19. Key factors include repeat infections, abdominal pain/diarrhea during infection, and long COVID. 🦠🧠 🔗:
https://ow.ly/gQCL50YFE4t
about 1 month ago
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💊GLP-1 drugs like Ozempic and Wegovy have far-reaching health benefits beyond weight loss. In a new nationwide cohort study, researchers from Beth Israel Deaconess Medical Center are adding one more to that list: Prevention of ulcers in the gut! 🔗:
https://ow.ly/FSJ450YBJUt
about 1 month ago
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🧪 Plastic exposure is unavoidable. As plastics break down into micro‑ and nanoplastics, they spread through water, soil, and air—and when ingested, may disrupt gut microbes and mucosal barriers, driving inflammatory and carcinogenic effects. ⚠️🦠 🔗:
https://ow.ly/xrHv50YBJuM
about 1 month ago
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📊 New multicenter data show peripancreatic vascular involvement is common in autoimmune pancreatitis—and highly responsive to glucocorticoids. Monitoring can help prevent life‑threatening gastric varices. 💊🩸 🔗:
https://ow.ly/tfp050YBJiH
about 1 month ago
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📊 Real‑world TORUS study: after anti‑TNF failure in UC, tofacitinib and ustekinumab showed similar effectiveness. Tofacitinib may be favored after multiple biologic failures or primary biologic nonresponse. 🔍✅ Read More:
https://ow.ly/Fhfc50YyRGx
about 1 month ago
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🧪 In this Phase 2a study in Asian patients with MASLD: the THR‑β agonist HSK31679 significantly reduced liver fat content after 12 weeks—greatest with 80 mg and 160 mg. ✅ The treatment was well tolerated, with no AE‑related discontinuations. Read More:
https://ow.ly/LBj550YyRpx
about 1 month ago
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🧬 Who should be treated for MASLD? This Hepatology original research article explores a practical criteria set—combining FIB‑4, transient elastography, diabetes, and overweight status—to better guide treatment decisions. 📖✨ Read More:
https://ow.ly/Khfe50YyR2o
about 2 months ago
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🌍 April 2026 Editors Essential Reading 📘 This Global NASH/MASH Council study projects that by 2040, the clinical, economic, and humanistic burden of MASH will more than double worldwide—underscoring the urgent need for action. 🚨 Read More:
https://ow.ly/f8yR50YyQrU
about 2 months ago
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🗣️ The newest issue of CGH is here!! ➡️
https://ow.ly/6AbI50Yy7w6
about 2 months ago
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📌 First meta-analysis on recompensation in decompensated cirrhosis 🔍 More common in viral etiologies & lower MELD 📉 Linked to lower risk of HCC & death ✅ A meaningful clinical endpoint Read more here:
https://ow.ly/tYnJ50YvNUo
#LiverTwitter
@wong__yujun @BavenoCoop
about 2 months ago
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🌟A survey of 54,127 participants from 26 countries identified four dietary clusters associated with global IBS prevalence and severity. The findings highlight regional dietary patterns and their association with IBS. @DipeshVasant 🔗:
https://ow.ly/6qOf50YvMM0
about 2 months ago
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📱 Can digital health expand #CRC screening? In the BLITZ study, a smartphone‑based FIT showed feasible use and diagnostic performance comparable to lab FITs for advanced neoplasms, supporting it as an adjunct screening option. #CRCAwarenessMonth 🔗:
https://ow.ly/HX6E50YvoBt
#CRC
#CRCAwarenessMonth
about 2 months ago
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🗣️In a survey of 54,127 participants across 26 countries, four dietary clusters linked to global #IBS prevalence and severity were identified. These findings highlight international dietary patterns and their association with IBS. @DipeshVasant 🔗:
https://ow.ly/XzPe50YpHsY
2 months ago
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📣 Calling all early-career GIs and PhDs! The AGA Journals are now accepting applications for a one-year editorial fellowship program focused on editorial training and leadership development. ⏰ Apply by 04/30/2026 🔗 Details and application:
https://ow.ly/fmRZ50YrtyR
2 months ago
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🚨#qFibrosis shows 89.2% repeatability (κ=0.88) and 86.5% reproducibility (κ=0.85) in liver fibrosis scoring, matching human pathologist agreement. The AI platform addresses variability in MASH trials, enabling standardized histological assessment. 🔗:
https://ow.ly/miua50YpGRV
2 months ago
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📱 Can digital health expand #CRC screening? In this BLITZ study, a smartphone‑based FIT showed feasible use and diagnostic performance comparable to lab FITs for advanced neoplasms, supporting it as an adjunct screening option. #CRCAwarenessMonth 🔗:
https://ow.ly/siEs50YqpuP
#CRC
2 months ago
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🌟Which therapies improve survival in severe alcohol‑associated hepatitis? A new systematic review highlights corticosteroids as first‑line treatment and evaluates emerging combination strategies. 🔗:
https://ow.ly/kuog50YpGJq
2 months ago
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✴️The March issue of #CGH is now online! This issue includes: 🔸A study on the effect of weight loss on patients with Gastrointestinal & Liver Disease 🔸A review on wearable technologies in #IBD 🔸Research on neoplasia detection rates 🔸...And more! 🔗:
https://ow.ly/HeGe50Ym6VX
#CGH
#IBD
3 months ago
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🌟CVE provides a means for automated ulceration and mucosal injury quantitation that shows conceptual agreement with SES-CD. CVE offers new capabilities to improve the granularity and personalization of endoscopic disease assessment in CD. 🔗:
https://ow.ly/kmpw50YhhoM
3 months ago
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A growing body of evidence suggests microplastics & nanoplastics may affect GI and liver health. A comprehensive @AGA_CGH review found microplastics linked with inflammation, gut dysbiosis, liver disease and possibly GI cancers ➡️
https://ow.ly/j41w50YhkmU
@dutta_priyata @AGA_GIHN
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3 months ago
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‼️New data show acne is a common and impactful side effect of JAK inhibitors in IBD—highlighting the need for early recognition and proactive management. 🔗:
https://ow.ly/szta50YhgEN
@Sash_Honap @PeyrinBiroulet @ibdseb @eathar_s @shahidadin1 @TakuKobayashiM1 P7278 @PolychronisP
3 months ago
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🧬“Distal eosinophilia predicts PPI response in EoE, while proximal‑predominant patterns predict nonresponse. Distribution may reflect distinct phenotypes and guide care.” @walterchanmd @mayssanmuftah 🔗:
https://ow.ly/tHtp50Y8M0J
3 months ago
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🗣️"Patients with both adenomas and significant serrated polyps face a higher risk of advanced neoplasia than those with either alone. They may benefit from shorter colonoscopy surveillance intervals than current guidelines recommend." 🔗:
https://ow.ly/UMmf50Y8Lig
3 months ago
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🛎️"Dynamic FIB-4 changes are linked to liver fibrosis progression and adverse outcomes in MASLD. Regular monitoring may support early risk detection and management." 🔗:
https://ow.ly/k6vc50Y8KKB
3 months ago
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✅"Global cohort of inpt #cirrhosis with external validation showing bili, INR cutoffs for defining liver failure & important impact of #infections & #HE" 🔗:
https://ow.ly/tbFM50Y8KBH
3 months ago
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🗣️New research found pediatric-specific cutoffs for the fatty liver index and hepatic steatosis index to help diagnose MASLD. These markers may improve early detection and risk stratification of MASLD in youth 🔗:
https://ow.ly/PVG850Y52aZ
3 months ago
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💡NILDAs are effective alternatives to liver biopsy for fibrosis assessment in MASLD and may serve as a tool to identify patients who are candidates for newer therapies. @RichSterlingMD 🔗:
https://ow.ly/LIr950Y51kR
3 months ago
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🚨 The newest issue of #CGH is now available! Check it out! 🔗:
https://ow.ly/Eu5T50Y4WyG
3 months ago
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‼️This new #CGH article observed HCC incidence rates declined and mortality plateaued in the US! 📰 Check out the press coverage:
https://ow.ly/2JsR50Y0RpM
📝 Read the article:
https://ow.ly/wQEr50Y0RpN
4 months ago
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🛎️AMR is rising in patients with cirrhosis. Multidisciplinary effort is crucial to combat AMR and manage bacterial infections in cirrhosis. 🔗 Read More:
https://ow.ly/aMJS50Y0Ep0
4 months ago
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🧬Etrasimod shows strong induction & maintenance efficacy in moderate–severe endoscopic UC, with potential continued improvement beyond 12 weeks—promising news for patients and clinicians. 🔗 Read more:
https://ow.ly/YcVz50Y0Efj
4 months ago
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💠New #CGH article on Night-shift workers showing a strikingly high prevalence of IBS and functional dyspepsia. 📰 Check out the press coverage:
https://ow.ly/MGJI50Y0R8z
📝 Read the article:
https://ow.ly/EqzV50Y0R8A
#CGH
4 months ago
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💠New #CGH article on Night-shift workers showing a strikingly high prevalence of IBS and functional dyspepsia. 📰 Check out the press coverage:
https://ow.ly/tWJb50Y0R3r
📝 Read the article:
https://ow.ly/q8OS50Y0R3q
#CGH
4 months ago
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📱Among 654 participants offered both tests, 55% used the smartphone FIT (76% valid) and 98% used the lab FIT. Overall, 89% found the smartphone test useful. Main reasons for not using it were technical issues or general concerns. Sensitivity matched the lab FIT. 🔗:
https://ow.ly/2N3B50XWI7H
4 months ago
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💭nCPAP reduces hypoxia risk and stabilizes O₂ levels in patients with obesity during sedated upper GI endoscopy, supporting its routine use in high‑risk patients. More studies should explore wider clinical use. 🔗:
https://ow.ly/K83M50XWHN3
4 months ago
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