Zhenzhen Wu
@zhenzhenwu.bsky.social
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Our new preprint is now on BioRxiv! Very excited to share this this work. Come take a look at what we have been working on! 😊
add a skeleton here at some point
4 months ago
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reposted by
Zhenzhen Wu
Simon Bekker-Jensen lab
4 months ago
New preprint out! Our latest work on how ZAKα is activated by stalled or/and collided ribosomes is now online🎉.
#Ribosome
#RibotoxicStressResponse
#ZAKα
#Translation
#mRNA
www.biorxiv.org/content/10.1...
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ZAKα is a sensor of mRNA stasis at the ribosomal exit channel
Despite a growing interest in the ribotoxic stress response (RSR), it remains unknown how the upstream p38 and JNK-activating MAP3 kinase ZAKα senses translational impairment. Combining Alphafold3 pre...
https://www.biorxiv.org/content/10.1101/2025.11.22.689755v1.full
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