Veterinary Cancer Health
@vetcancerhealth.bsky.social
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Francisco Avarez Berger DVM, MS, DACVIM (Oncology) Veterinary Medical Oncologist
Primary pulmonary histiocytic sarcoma with nodal and esophageal metastasis in a dog—imaging and anatomopathological aspects
link.springer.com/article/10.1...
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Primary pulmonary histiocytic sarcoma with nodal and esophageal metastasis in a dog—imaging and anatomopathological aspects - BMC Veterinary Research
Background This report presents a case of esophageal and nodal metastasis in a primary pulmonary histiocytic sarcoma in a dog. Histiocytic sarcoma is a malignant neoplasm originating from histiocytic ...
https://link.springer.com/article/10.1186/s12917-025-05058-3
about 1 month ago
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Impacts of exoprosthesis use in dogs with partial amputation and limb malformations: a systematic review
www.frontiersin.org/journals/vet...
about 1 month ago
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Tumor immune microenvironment and immune phenotypes in PD-L1-tested canine urothelial carcinoma.
link.springer.com/article/10.1...
about 1 month ago
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Definitive Radiotherapy as a Treatment for Presumed Brainstem Meningioma Causing Collet-Sicard Syndrome in Dogs: A Case Series.
onlinelibrary.wiley.com/doi/10.1111/...
about 1 month ago
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The role of regulatory T cells in central nervous system diseases in dogs: fighting with a double-edged sword toward translational discoveries
pmc.ncbi.nlm.nih.gov/articles/PMC...
about 1 month ago
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Novel organoid-based exploration reveals the role of LMTK3/FADS2 signaling in metastatic breast cancer progression in felines and humans.
www.nature.com/articles/s41...
about 1 month ago
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Definitive Radiotherapy as a Treatment for Presumed Brainstem Meningioma Causing Collet–Sicard Syndrome in Dogs: A Case Series
onlinelibrary.wiley.com/doi/full/10....
about 1 month ago
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Diagnostic challenges of polyclonal B-cell lymphocytosis in an English Bulldog (PBLEB) and outcome following splenectomy
www.sciencedirect.com/science/arti...
about 1 month ago
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Neoplasms with splenic involvement in dogs at necropsy: Macroscopic presentation patterns in 262 cases
www.sciencedirect.com/science/arti...
about 1 month ago
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In dogs with primary liver tumors, additional liver masses identified on preoperative imaging or surgical exploration are most often benign
avmajournals.avma.org/view/journal...
about 1 month ago
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CT and MRI Features of Aortic Body Paragangliomas in 44 Dogs
onlinelibrary.wiley.com/doi/10.1111/...
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https://onlinelibrary.wiley.com/doi/10.1111/vru.70106
about 1 month ago
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Comparative histologic survey and transcriptomic investigation into canine prostate carcinoma
www.sciencedirect.com/science/arti...
about 1 month ago
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Suppressive effects on metastasis and tumor growth by the knockout of chemokine receptors in a canine cutaneous lymphoma model
www.jstage.jst.go.jp/article/jvms...
about 1 month ago
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Ovarian Remnant Syndrome in Bitches and Queens: Clinical Aspects and Potential Neoplastic Transformations
www.mdpi.com/2076-2615/15...
about 1 month ago
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Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy
www.frontiersin.org/journals/vet...
about 1 month ago
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Characterization of host immune cell infiltrate in human CAR T cell-mediated xenogeneic graft versus host disease in NSG mice
journals.sagepub.com/doi/10.1177/...
about 1 month ago
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Brain metastases from endometrial carcinoma in two dogs.
link.springer.com/article/10.1...
about 1 month ago
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Thoracoscopic resection of cranial mediastinal masses: Retrospective study in 17 cats.
onlinelibrary.wiley.com/doi/10.1111/...
about 1 month ago
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The immune microenvironment in tumors: focus on canine and feline spontaneous neoplasms
www.frontiersin.org/journals/vet...
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Frontiers | The immune microenvironment in tumors: focus on canine and feline spontaneous neoplasms
Companion animals develop spontaneous tumors with biological and immunological features closely resembling human cancers. The tumor microenvironment (TME), p...
https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2025.1674694/full
about 1 month ago
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Sequence Diversity and Expression Profiles of T Cell Receptor Beta Chain Constant Genes TRBC1 and TRBC2 in Canine Lymphoid Tumour Cell Lines and Normal Lymphocytes.
onlinelibrary.wiley.com/doi/10.1111/...
about 1 month ago
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Is PTEN rs397510595 an Unexpected Guardian in Canine Mammary Neoplasia?
www.mdpi.com/1422-0067/26...
about 1 month ago
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Investigation of the "R" tumor margin classification and prognostic factors in apocrine gland anal sac adenocarcinoma of dogs
onlinelibrary.wiley.com/doi/10.1111/...
about 2 months ago
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Neoplasms with splenic involvement in dogs at necropsy: Macroscopic presentation patterns in 262 cases.
www.sciencedirect.com/science/arti...
about 2 months ago
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The distribution of neoplasia in Danish cats – data from the Danish Veterinary Cancer Registry
journals.sagepub.com/doi/10.1177/...
about 2 months ago
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Systemic mRNA vaccines elicit rapid immune activation in canine brain tumors.
jitc.bmj.com/content/13/1...
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Systemic mRNA vaccines elicit rapid immune activation in canine brain tumors
Malignant glioma is considered invariably recalcitrant, thus necessitating development of new therapeutic approaches. Spontaneously arising canine glioma exhibits important molecular and pathological ...
https://jitc.bmj.com/content/13/11/e011817
about 2 months ago
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Comparative transcriptomic analysis of tumor- infiltrating canine natural killer cells and candidate biomarkers from first-in-dog NK immunotherapy trials.
www.frontiersin.org/journals/imm...
about 2 months ago
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Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.
www.frontiersin.org/journals/imm...
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Frontiers | Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma
BackgroundWe have previously shown inhaled IL-15 is associated with anti-tumor responses in dogs with metastatic osteosarcoma (OSA) and melanoma. We evaluate...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1672790/full
about 2 months ago
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Nanobody-based canine PD-L1-targeting immune checkpoint inhibitors for cancer therapy in dogs
www.cell.com/molecular-th...
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Nanobody-based canine PD-L1-targeting immune checkpoint inhibitors for cancer therapy in dogs
Di Palma Subran and colleagues developed novel anti-canine immune checkpoint inhibitors based on single domain antibodies (sdAbs). Best candidates combined two sdAbs and an Fc-region of canine origin....
https://www.cell.com/molecular-therapy-family/oncology/fulltext/S2950-3299(25)00105-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2950329925001055%3Fshowall%3Dtrue
about 2 months ago
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Machine Learning-Based Risk Prediction for Feline Mammary Tumours: A Comprehensive Epidemiological Analysis Using Multi-Model Ensemble Approach
onlinelibrary.wiley.com/doi/10.1111/...
about 2 months ago
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Hamartomas of the alimentary tract in dogs: A case series
journals.sagepub.com/doi/10.1177/...
about 2 months ago
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Clinical and histological characterization of 19 chondro-osseous respiratory epithelial adenomatoid hamartomas and 2 respiratory epithelial adenomatoid hamartomas in dogs
journals.sagepub.com/doi/10.1177/...
about 2 months ago
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Canine Hemangioblastoma: Case Series and Literature Review
www.mdpi.com/2076-2615/15...
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https://www.mdpi.com/2076-2615/15/20/3010
about 2 months ago
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Preparation of a camel-canine chimeric antibody against canine B-cell lymphoma
amb-express.springeropen.com/articles/10....
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Preparation of a camel-canine chimeric antibody against canine B-cell lymphoma - AMB Express
Canine B-cell lymphoma is a malignant hematologic neoplastic disease, with diffuse large B-cell lymphoma being the predominant subtype. This subtype highly expresses canine CD20 on its surface. Most c...
https://amb-express.springeropen.com/articles/10.1186/s13568-025-01974-7
about 2 months ago
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Combined half-body irradiation and chemotherapy for two dogs with relapsed high-grade B-cell lymphoma
www.jstage.jst.go.jp/article/jvms...
about 2 months ago
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PRC1, CDCA3, and CDC20 are upregulated and Treg numbers are decreased in canine massive hepatocellular carcinoma
bmcvetres.biomedcentral.com/articles/10....
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PRC1, CDCA3, and CDC20 are upregulated and Treg numbers are decreased in canine massive hepatocellular carcinoma - BMC Veterinary Research
Background The mechanisms underlying the development and prognosis of hepatocellular carcinoma (HCC) differ between dogs and humans. Although genetic alterations can cause carcinogenesis, the genetic ...
https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-025-05103-1
about 2 months ago
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Possible involvement of cerebrospinal fluid drop metastasis in the survival of French bulldogs after radiotherapy for presumed glial brain tumors.
www.openveterinaryjournal.com?mno=252563
about 2 months ago
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Electrochemotherapy for canine prostatic carcinoma treatment.
www.openveterinaryjournal.com?mno=252217
about 2 months ago
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CXCL8 mediates macrophage migration in canine oral malignant melanoma
www.nature.com/articles/s41...
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CXCL8 mediates macrophage migration in canine oral malignant melanoma - Scientific Reports
Scientific Reports - CXCL8 mediates macrophage migration in canine oral malignant melanoma
https://www.nature.com/articles/s41598-025-22749-x
about 2 months ago
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Editorial: Cancer in domestic, exotic and wild animals: new horizons in tumorigenesis, diagnosis, prognosis and therapeutics through comparative oncology.
www.frontiersin.org/journals/vet...
about 2 months ago
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Immunomodulatory vaccine demonstrates therapeutic efficacy across cancer types.
www.nature.com/articles/s41...
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Immunomodulatory vaccine demonstrates therapeutic efficacy across cancer types - Scientific Reports
Scientific Reports - Immunomodulatory vaccine demonstrates therapeutic efficacy across cancer types
https://www.nature.com/articles/s41598-025-21924-4
about 2 months ago
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Comparative genomic analysis of multiple mammary tumors from a single dog: whole-genome sequencing study.
irishvetjournal.biomedcentral.com/articles/10....
about 2 months ago
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Role of companion dogs in cancer immunotherapy development
academic.oup.com/jimmunol/art...
about 2 months ago
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Stabilization of G-Quadruplexes Modulates the Expression of DNA Damage and Unfolded Protein Response Genes in Canine Lymphoma/Leukemia Cells.
www.mdpi.com/1422-0067/26...
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https://www.mdpi.com/1422-0067/26/20/9928
about 2 months ago
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Extended Survival in a Dog with Primary Bone Hemangiosarcoma Following Treatment with Neoadjuvant Oncolytic Virotherapy and Standard of Care.
www.mdpi.com/2306-7381/12...
about 2 months ago
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Extended Survival in a Dog with Primary Bone Hemangiosarcoma Following Treatment with Neoadjuvant Oncolytic Virotherapy and Standard of Care.
www.mdpi.com/2306-7381/12...
about 2 months ago
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Matrine as a potent inhibitor of canine mammary tumors: Insights from network pharmacology, molecular docking, molecular dynamics and in vitro analysis.
www.sciencedirect.com/science/arti...
about 2 months ago
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Esophageal squamous cell carcinoma invading the gastric cardia in a cat.
pmc.ncbi.nlm.nih.gov/articles/PMC...
about 2 months ago
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The outcomes of Swenson's pull-through in six cats with colorectal adenocarcinoma.
www.jstage.jst.go.jp/article/jvms...
about 2 months ago
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Metronomic Chemotherapy in Dogs and Cats: Mechanisms, Indications, and Clinical Perspectives
www.mdpi.com/2072-6694/17...
about 2 months ago
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Age-related obesity and inflammaging in cats
www.frontiersin.org/journals/vet...
about 2 months ago
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