Harvard researchers studied human patients to find that a decade after a precancerous colon growth is removed, the gut microbiome may still bear its mark, and that diet and activity may play a key role in future cancer risk. hsph.harvard.edu/news/colorec...

In human-relevant research, scientists at the Wellcome Sanger Institute mapped IBD risk across 2.2 million individual human cells to pinpoint disease-driving genes. www.sanger.ac.uk/news_item/st...

Trinity College Dublin found that immune cell metabolism determines whether TB stays dormant or turns deadly — discovered through human samples, where the answers to human disease actually live. www.technologynetworks.com/proteomics/n...

Linköping University built an artificial heart muscle cell from conductive plastic that replicates cardiac electrical signals, opening a path to smarter implants and human-relevant heart research. www.technologynetworks.com/cell-science...

Human donor tissue reveals that early pancreatic lesions don't behave like cancer until something triggers the switch — a finding made possible by studying actual human tissue. www.technologynetworks.com/cancer-resea...

Dutch scientists used patient-derived heart cells and not animals to model inherited heart disease, showing that targeted RNA therapy corrected key defects, offering a path toward treating genetic cardiomyopathies. www.technologynetworks.com/proteomics/n...

A human stem cell-derived inner ear-on-a-chip is helping University of Miami researchers unlock why we lose hearing permanently — studying human biology directly, where the answers actually lie. news.med.miami.edu/inner-ear-on...

Huge win for animals Wisconsin’s Ridglan Farms, a major beagle supplier for animal testing, is closing. 475 remaining dogs are being transferred to rescue groups and prepared for adoption. A big step toward a more humane future for animals and research. www.seattletimes.com/business/wis...

QIMR Berghofer's AI tool STimage detects hidden cancer markers in routine human tissue samples with high accuracy — precision diagnostics built entirely on human data, not animal testing. www.technologynetworks.com/diagnostics/...

Polish researchers built human blood vessel networks using magnetic fields — a human-based platform that outperforms animal experiments for drug testing.

Mouse biology can't explain human diabetes — so researchers studied islets from 299 people and found a direct cellular link to type 2 diabetes risk.

Animal free research at UCSF and Imperial College London used EEG and MRI in human volunteers to show that a single psilocybin dose reshapes human brain structure and boosts well-being for weeks.

University of Cambridge researchers used human stem cell organoids to identify a potential way to reverse nerve damage once thought permanent — more ethical and accurate than animal testing.

Brown University researchers found serotonin reduces "belief stickiness" in human volunteers, reshaping how OCD is understood and pointing toward more effective treatments. www.technologynetworks.com/neuroscience...

We did it — 25+ years of cruel baboon experiments at U of Maryland-Baltimore are over, shut down after CAARE exposed the cruelty and scientific irrelevance. www.caareusa.org/caare_ended_...

Erasmus MC used human organ organoids and AI to rapidly identify antiviral drug candidates — a more ethical and scientifically accurate approach than testing on animals. amazingerasmusmc.nl/gastro-enter...

Stanford University researchers developed a blood test that maps the cellular landscape around tumors using human cancer data, potentially transforming how treatment response is monitored. www.technologynetworks.com/cancer-resea...

Human based research shows that brain waves at age 9 may predict who later develops anxiety or depression, offering a path to earlier screening and support before symptoms appear. www.technologynetworks.com/neuroscience...

UCSF researchers mapped 200K human cells at the maternal-fetal interface, uncovering new cell types tied to preeclampsia, preterm birth & miscarriage. www.technologynetworks.com/cell-science...

Stanford Medicine used brain imaging to identify two biological migraine subtypes that could transform treatment decisions. This human study challenges how migraines are currently classified. www.technologynetworks.com/neuroscience...

Cochrane's review of 20,000+ patients finds Alzheimer's amyloid-clearing drugs offer no meaningful benefit and raise brain risks. www.sciencedaily.com/releases/202...

A new animal-free study from São Paulo State University showed that vitamin D as a neoadjuvant to chemotherapy improved complete cancer disappearance in breast cancer patients from 24% to 43%. www.sciencedaily.com/releases/202...

University of Calgary analyzed human tumor cells from myeloma patients across three continents to understand why cancer returns after immunotherapy — bringing personalized, more targeted treatments closer to reality. www.technologynetworks.com/cancer-resea...

Rather than just repeating flawed experiments on male animals with female animals, Garvan Institute & UNSW Sydney used human single-cell analysis of both sexes to reveal the genetic basis of why women are more prone to autoimmune disease.

Queen Mary University of London led the world's largest blood protein genetics study using data from 78,000+ human participants, revealing new disease mechanisms and drug repurposing opportunities.

In animal-free research, Yale School of Medicine analyzed genomes from 1.4M women to map the genetics of endometriosis, identifying 80 risk regions and pointing toward treatments for this disease lacking therapies. www.technologynetworks.com/genomics/new...

University of Copenhagen used human brain imaging to show that amygdala reactivity to fear predicts psychiatric relapse risk — insights into mental health that only human-focused research can deliver. www.technologynetworks.com/neuroscience...

McGill University's AI tool SIDISH identifies the most dangerous cells in human tumors and predicts drug targets — cancer research driven entirely by human data, not animal testing. www.technologynetworks.com/informatics/...

Charité – Universitätsmedizin Berlin used human brain imaging to show stress drives drinking in young men but not women — insights into alcohol use disorder that only human research can deliver. www.technologynetworks.com/neuroscience...

McGill University used postmortem human brain tissue and single-cell genomics to identify the specific brain cells altered in depression — findings only possible through human-focused research. www.sciencedaily.com/releases/202...

Mayo Clinic's 3D-bioprinted human skin model has gained FDA attention as a preclinical testing alternative — avoiding cruel animal testing that fails to predict human outcomes nearly 90% of the time. newsnetwork.mayoclinic.org/discussion/3...

NYU Langone Health sequenced gut bacteria from 674 melanoma patients and predicted cancer recurrence with up to 94% accuracy — a breakthrough only possible through direct human research. www.technologynetworks.com/cancer-resea...

Karolinska Institutet analyzed human twin registry data to show childhood trauma significantly raises treatment-resistant depression risk — human-relevant findings without cruel animal tests. www.technologynetworks.com/neuroscience...

Keck School of Medicine used human genomic data from 470,000+ participants to confirm that extreme pregnancy nausea is genetic, not psychological — insights only possible through human research. www.technologynetworks.com/genomics/new...

Former animal lab workers hosted by Justify describe the psychological toll of a system built on animal abuse, secrecy and flawed science; while highlighting they had no idea non-animal research methods existed, offering a choice for scientists to pursue. www.youtube.com/watch?v=8tpu...

CAARE’s president Barbara Stagno argues that animal research needs radical reform, not better PR. With major government agencies promoting phase outs of animal research, we’re in a pivotal moment to work towards its end. www.the-scientist.com/animal-resea...

Nearly 1,500 beagles bred for research at Wisconsin's Ridglan Farms — a facility that agreed to surrender its breeding license to avoid felony charges — will now enjoy freedom after being purchased by animal welfare groups. pbswisconsin.org/news-item/an...

Keck Medicine of USC showed human population data can reveal how occasional binge drinking sharply increases liver damage risk, offering more humane and directly relevant insights than animal testing www.technologynetworks.com/applied-scie...

University of Sussex used human blood analysis to detect aggressive brain tumors earlier and more accurately, revealing diagnostic advances unobtainable from animal testing www.technologynetworks.com/diagnostics/...

Medical University of South Carolina used NASA-developed MRI tech and human tissue imaging to uncover a hidden brain drainage hub — studying humans directly rather than animals, for results that are more accurate and relevant to human disease. www.sciencedaily.com/releases/202...

Gladstone Institutes used CRISPR in human T cells drawn directly from human donors to map HIV's interactions with the human genome — more accurate and relevant than animal experiments. www.technologynetworks.com/drug-discove...

Flinders University studied human immune data to explain VITT, a rare and serious clotting disorder, to guide safer vaccine development through human-based science www.sciencedaily.com/releases/202...

McGill University study used computational analysis of human brain scans and not flawed animal studies to show psychedelics boost brain connectivity rather than suppress it. www.technologynetworks.com/drug-discove...

Princeton University finds high-fat conditions make breast cancer more aggressive using human-based tumor models. www.technologynetworks.com/cancer-resea...

Institute of Science Tokyo’s AI model uses human cell data to predict disease outcomes, helping identify harmful cells and guide targeted therapies. www.technologynetworks.com/informatics/...

Human research from the Keck School of Medicine of USC used AI + MRI data from 500+ patients to reveal how the brain reorganizes after stroke to compensate for injury. www.sciencedaily.com/releases/202...

Human research from the Keck School of Medicine of USC used AI + MRI data from 500+ patients to reveal how the brain reorganizes after stroke to compensate for injury. www.sciencedaily.com/releases/202...

NASA’s Artemis II used human bone marrow cell-based organ chips to study space radiation, delivering more accurate and human-relevant insights than outdated experiments sending animals into space. futurism.com/space/nasa-a...

University of Maryland School of Medicine developed a cervix-on-a-chip using human cells to study sexually transmitted infections without cruel and inadequate animal tests. www.insideprecisionmedicine.com/topics/preci...

UC Berkeley created an organ-on-a-chip using human cells to replicate decades of aging in days, delivering more humane and scientifically accurate insights than animal testing. medicalxpress.com/news/2026-03...