UCSF’s clinical trial shows daily coffee may lower AFib recurrence by 39%, highlighting the value of human-based clinical evidence over outdated and cruel animal tests. www.sciencedaily.com/releases/202...

Utrecht University’s 4D bioprinting creates more realistic human-based tissue models, improving poor drug testing results that are based on animal testing. www.uu.nl/en/news/4d-p...

Huge win: CDC ends all monkey testing and embraces more ethical, human-based science — a big step forward for animals and better research. www.science.org/content/arti...

Weill Cornell Medicine and University of Adelaide unveil GoT-Multi, a human-based tool that tracks cancer evolution at single-cell detail, reducing use of animal tests. www.technologynetworks.com/proteomics/n...

University of Glasgow developed a bioengineered human bone marrow model that improves leukemia therapy testing and reduces reliance on animal research. medicalxpress.com/news/2025-11...

UC Davis Health study links anxiety to lower choline levels in the brain, advancing human-based understanding of mental health without poorly translatable animal tests. www.technologynetworks.com/neuroscience...

Instead of cruel animal experiments, University of Sydney used advanced fMRI in humans to map pain response, revealing endocannabinoid pathways for targeted treatments. www.sciencedaily.com/releases/202...

Certara’s AI platform aligns with FDA’s new policy to phase out animal tests by using sophisticated computer modeling to more accurately predict drug responses. technical.ly/sponsored-ar...

Duke‑NUS created BrainSTEM , a detailed human brain cell atlas guiding better, animal-free Parkinson’s therapies by improving accuracy and safety of lab-grown human models. www.sciencedaily.com/releases/202...

Penn’s tumor‑on‑a‑chip uses modern, animal-free research to show how CAR T cells attack solid tumors, advancing understanding of immunotherapy. penntoday.upenn.edu/news/tumor-c...

On Tuesday the UK unveiled a sweeping and detailed plan to phase out animal testing for drugs in multiple key areas by shifting to superior and humane nonanimal methods. www.drugtargetreview.com/news/190470/

Cincinnati Children’s Hospital and Roche develop patient-derived mini livers that reveal drug toxicity missed in animal testing, improving human-relevant safety research. www.sciencedaily.com/releases/202...

University of Sheffield uses patient-derived models instead of animal tests to reveal patient-specific treatment responses and advance neurodegenerative drug discovery. www.technologynetworks.com/drug-discove...

German researchers created patient-derived brain organoids to model lissencephaly, a rare brain disorder, revealing new insights without cruel animal testing. www.technologynetworks.com/neuroscience...

Wyss Institute developed a human-based uterus-on-a-chip to study heavy menstrual bleeding, improving understanding of the disorder without inapplicable animal studies. www.thecrimson.com/article/2025...

Baylor researchers used human nasal organoids instead of cruel and outdated animal experiments to study how beneficial bacteria in the nose protect against infection. www.technologynetworks.com/immunology/n...

University of Fukui conducted an animal-free study to find DNA methylation “scars” from childhood trauma. These human-based biomarkers open new paths for early screening and treatment. www.technologynetworks.com/genomics/new...

One of the largest U.S. breeders of research dogs is shutting down after documented abuse—disrupting the supply chain and signaling rising demand for ending animal experiments. www.science.org/content/arti...

South Korean researchers developed a retina-on-a-chip to study retinal vein occlusion. The chip accurately mimics human retinal structure and disease progression to advance the search for new treatments without animal tests.

UVA Health’s human-based biomarker research advances early detection of interstitial lung disease —another example of how cruel animal testing fails to accurately model human biology.

MIT’s new miBrains use patient-derived human tissue to model brain disease and test drugs, offering a more ethical and scientifically robust alternative to animal experiments:

McGill University and the Douglas Institute used human-based research to identify brain-cell changes linked to depression, guiding future treatments.

Karolinska Institutet and Queen Mary researchers use human-based models to reveal how fat tissue structure fuels ovarian cancer spread.

UC Irvine built a 3D artificial colon from human cells to improve drug testing accuracy and replace cruel and outdated animal studies. news.uci.edu/2025/10/15/u...

The University of Rochester created a brain-on-a-chip from human tissue to study how sepsis harms the brain—advancing neurodegenerative research without animal testing. medicalxpress.com/news/2025-10...

Tell NIH and UMB to end to cruel, unnecessary, and outdated experiments that cut babies out of pregnant baboons. www.caareusa.org/end_abominab...

Without animal testing, Mass General Brigham found memantine improved social behavior in autistic youth in a clinical trial that used human biomarkers and neuroimaging. www.technologynetworks.com/drug-discove...

University of East Anglia created a blood test that diagnoses chronic fatigue syndrome with 96% accuracy using human-based genomic data, and no animal testing. www.technologynetworks.com/diagnostics/...

Hesperos and Bayer created a human-on-a-chip system to study the impact of stress on the brain —an ethical, animal-free breakthrough in stress-induced cognitive dysfunction. www.morningstar.com/news/busines...

The University of Rochester created a brain-on-a-chip from human tissue to study how sepsis harms the brain—advancing neurodegenerative research without animal testing. medicalxpress.com/news/2025-10...

Integra Therapeutics and Pompeu Fabra University used AI and human-cell testing to design powerful new genome-editing proteins—advancing superior, human-based science without using animals. www.technologynetworks.com/biopharma/ne...

Mass General Brigham studied human patients and not animals to compare the ability of two forms of ketamine to reduce treatment-resistant depression. www.technologynetworks.com/drug-discove...

University of Cambridge scientists and collaborators used a new brain imaging method to map Parkinson’s-linked proteins in post-mortem human brains, advancing human-based research without cruel animal testing. www.technologynetworks.com/proteomics/n...

We celebrate the life of Dr. Jane Goodall, environmentalist and animal advocate, who died last week at 91. She championed animal rights, conservation, and inspired global compassion. www.vox.com/future-perfe...

King’s College London & collaborators studied human COVID patients receiving inhaled heparin and demonstrated reduced deaths and need for mechanical ventilation. www.sciencedaily.com/releases/202...

University of Rochester & NCATS bypassed cruel animal experiments and studied mother/infant blood samples to show prenatal PFAS exposure alters infant immune cells. ncats.nih.gov/news-events/...

Molecular Devices’ automated brain organoid system boosts reproducibility and scalability, advancing human-based neurodegenerative research without using animals. www.technologynetworks.com/neuroscience...

Mass General Brigham trial used human blood samples to show cocoa extract lowers inflammation with age—advancing science without animal use. www.technologynetworks.com/immunology/n...

Georgia Tech & Vanderbilt U’s lung-on-a-chip with a working immune system offers a superior, human-relevant alternative to animal testing. news.gatech.edu/news/2025/09...

MIT’s atlas of 3.5M brain cells from post-mortem donors reveals how gene regulation fails in Alzheimer’s— human-relevant insights that may slow memory decline. www.technologynetworks.com/genomics/new...

Max Delbrück Center introduces Flexynesis, a human-based, animal-free deep learning tool that integrates multi-omics and imaging data to guide personalized cancer therapy. www.technologynetworks.com/drug-discove...

New animal-free research from Ohio State University on long-term outcomes of psilocybin-assisted therapy for depression finds that 67% of participants were still in remission five years after therapy. www.technologynetworks.com/drug-discove...

Using only human research, the European Society of Cataract and Refractive Surgeons shows pilocarpine+diclofenac eye drops improve vision in far-sighted patients. www.sciencedaily.com/releases/202...

NIH launches $87M Standardized Organoid Modeling (SOM) Center to advance human-based organoid research—cutting animal testing & boosting biomedical progress. www.nih.gov/news-events/...

Researchers at the University of Technology Sydney 3D bioprinted mini-placentas, bypassing cruel and flawed animal experiments while advancing human-based research to prevent pregnancy complications. theconversation.com/3d-printed-m...

Penn State’s endometriosis researchers studied human patients and not inapplicable animal experiments to reveal that endometriosis patients have altered responses to stress. www.technologynetworks.com/diagnostics/...

Karlsruhe Institute of Technology’s miniaturized platform combines drug synthesis, testing, and analysis on a single chip, enabling human-relevant early-stage drug discovery without animal testing. www.technologynetworks.com/analysis/new...

HKUMed’s human respiratory organoids offer a more ethical and scientifically sound method to test SARS-CoV-2 antibodies and vaccines than using animals.

In a human study, Oregon Health & Science University showed that regular sleep halves the risk of clinical setbacks during heart failure recovery.

In animal-free research, Uppsala University scientists used AI to detect early prostate cancer missed by pathologists, offering improved treatment outcomes for patients.