📢Our MD simulation is out in Biophysical Journal! The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model. authors.elsevier.com/a/1mBGt_9FM7... #Microbiology #Biophysics

Our latest work is out in PNAS!🎉 We show that nonequilibrium polysome dynamics help drive sister chromosomes apart. The closing division septum also contributes via steric interactions.👇 www.pnas.org/doi/10.1073/... #MicroSky #Microbiology #Biophysics #CellBiology

Bacteria lack a mitotic spindle—how do they segregate chromosomes? 🤓 Using quantitative microscopy and modeling, we show that polysome (mRNA–ribosome) dynamics contribute to chromosome separation in E. coli, but septum closure and potentially DNA entropic segregation mechanisms are also involved.

New exciting findings on E. coli cell division: Using high throughput imaging 🔬 & stochastic modeling, we show that FtsZ—not FtsN—drives constriction at fast growth rates. Great collaboration with @arielamir.bsky.social and @KarPrathitha www.nature.com/articles/s41... #Microbiology #CellBiology