Microglia are the brain’s most dynamic cells, constantly extending and retracting their processes to monitor the parenchyma and respond to potential danger with inflammatory signaling. Our new study in @ScienceAdvances @science.org explores how these functions are regulated.

Very interesting paper in Science Advances by the Madry lab showing that the chloride channel Clic1 regulates morphodynamics and surveillance of #microglia via ERM proteins. These functions are chloride independent. www.science.org/doi/10.1126/...