JAK inhibitor exposure was not associated with reduced height in children treated for atopic dermatitis, juvenile arthritis, or inflammatory bowel disease. ja.ma/4bAXdZN

Among adults with #AtopicDermatitis, JAK inhibitor use was associated with more than double the 6-month risk of physician-recorded #Acne compared with Th2 cytokine inhibitor, with no difference seen for folliculitis or rosacea. ja.ma/4sYz6dt

#Acne prevalence among transmasculine patients ranged from 29.6% to 61.9% depending on methodology. 📌 This Review aims to summarize current literature for prevalence and factors associated with acne in transmasculine patients. ja.ma/49D2xKz

This case report describes a man in his 30s who was referred for the evaluation of a 3-month destructive process affecting the nail matrix and nail plate of the left thumbnail. ja.ma/3NssHat

Seborrheic #dermatitis in adults is positively associated with a range of other epithelial barrier diseases, including atopic dermatitis, #psoriasis, #rosacea, #celiac disease, and dry eye. ja.ma/49Mg7dq

Moderate to severe #Acne incidence was greatest within the first year after testosterone for transmasculine individuals vs cisgender comparators. ja.ma/3ZucdRy

Specific T-cell receptor clonotypes, especially Vb20 and Vg8, were associated with advanced-stage disease and poor survival in MF/SS. ja.ma/4abQiE3

Discordance between clinician- and patient-reported outcomes is common in Skin Chronic Graft-vs-Host Disease. Ade Adamson, MD, speaks with author Emily Baumrin, MD, MSCE, about how patient-reported measures may better predict survival. Listen now: ja.ma/49M1vdV

In cutaneous cutaneous chronic graft-vs-host disease, discordance in clinician vs patient treatment response was common, especially in sclerotic disease; both measures were independently associated with survival. ja.ma/3LEPsY4

Once-daily oral ICP-332, a tyrosine kinase 2 inhibitor, showed favorable safety and significantly improved disease severity versus placebo in adults with moderate to severe #AtopicDermatitis. ja.ma/45ZPrET

In this episode of the JAMA Dermatology Author Interviews podcast, Arash Mostaghimi, MD, MPH, discusses trends in advanced practice clinician involvement and specialty drug spending in dermatology with host Ade Adamson, MD, MPP. 🎧 Listen now: ja.ma/3LR4Ssa

Between 2013 and 2022, the share of #Dermatology specialty drug spending by advanced practice clinicians rose from 10% to 31%, driven by a faster increase in APC numbers and prescribing intensity compared to physicians. ja.ma/3NmRblg

Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4bw0Rnp

Once-daily oral ICP-332, a tyrosine kinase 2 inhibitor, showed favorable safety and significantly improved disease severity versus placebo in adults with moderate to severe #AtopicDermatitis. ja.ma/4qRwGeK

Eosinophilic fasciitis (EF) is a rare disease in which the fascia, the tissue that covers the muscles, becomes inflamed. 📄 This Patient Page describes the symptoms, diagnosis, and treatment of eosinophilic fasciitis. ja.ma/456KTwd

Case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments. ja.ma/49HVRuF

An adolescent female presented with 3 days of progressive abdominal pain and reported that a rash first appeared nearly 1 year earlier on her left wrist and gradually spread over several weeks. What is your diagnosis? ja.ma/4qItEcH

Transcutaneous auricular vagus nerve stimulation improved facial erythema, flushing, and related systemic symptoms among patients with patients with erythematotelangiectatic #rosacea compared to sham treatment. ja.ma/3Z01e20

Systematic review: Accurate classification of dermatologic conditions using International Classification of Diseases (ICD) codes is essential for research that uses large administrative datasets. ja.ma/4qANZRk

Among bionaive patients with #Psoriasis in Denmark, ustekinumab had superior drug survival compared with adalimumab and secukinumab over 5 years. ja.ma/45kP3AP

A woman in her 70s presented with a 5-year history of pruritic, thickened plaques involving the trunk and extremities. Despite intermittent treatment with antihistamines and glucocorticoids, the condition progressed. Read the full case report: ja.ma/49kbXJD

Psoriasis patients treated with ustekinumab had a lower five-year risk of developing cancer (excluding nonmelanoma skin cancer) compared to those on adalimumab, while risk for secukinumab was similar but limited by small sample size. ja.ma/49ooiMZ

Acne keloidalis nuchae (AKN) is a chronic skin condition characterized by inflamed hair follicles that can cause hair loss and substantial scarring. This Patient Page describes the symptoms, diagnosis, and treatment of AKN. ja.ma/4bfbuuD

Lamellar ichthyosis (LI) is a rare autosomal recessive disorder characterized by widespread, thick, platelike scales. This case report describes 2 siblings in their 20s with lamellar ichthyosis treated with acitretin and dupilumab. ja.ma/45mH99S

The EBSdart scoring tool reliably measures disease severity in epidermolysis bullosa simplex across age groups, showing strong interrater agreement and generalizability, and may aid future clinical trials and therapy development. ja.ma/49j9KhF

Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events. ja.ma/4phELs4

The EBSdart scoring tool reliably measures disease severity in epidermolysis bullosa simplex across age groups, showing strong interrater agreement and generalizability, and may aid future clinical trials and therapy development. ja.ma/44OsEvg

Viewpoint: #Melanoma in situ is a main contributor to melanoma overdiagnosis, and reframing it as a precancer could help mitigate emotional and physical harms for patients. ja.ma/3YbCjIG

In a case series of patients with severe alopecia areata, some who failed treatment with one or more Janus kinase inhibitors (JAKis) responded to a different JAKi, suggesting that switching JAKis may benefit nonresponders and support personalized therapy. ja.ma/4q0n6Xd

The ICD-10 code L80 was found to have high accuracy for identifying vitiligo, with the highest positive predictive value when codes are combined with treatment data. ja.ma/4q10ENy

This case report describes a man in his 30s who presented for evaluation of a 3-week history of irritation, redness, and photophobia in both eyes. ja.ma/3KOUwsx

The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree? 🔗 ja.ma/49dC70E

Patient-Reported Outcomes Measurement Information System (PROMIS) measures for pain, itch, social satisfaction, and isolation showed strong validity and tracked clinical improvements in adults with chronic skin disease. ja.ma/3LcjT7H

Latine patients with #HidradenitisSuppurativa report unmet wound care and pain management needs, frequent self-directed care, and barriers created by interpreter-mediated communication, supporting the need for improved multidisciplinary approaches. ja.ma/4b1j0cu

The numbers are in. The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree? 🔗 ja.ma/3KI8NY0

In this qualitative study, patient self-advocacy and access to Spanish-speaking clinicians facilitated quicker #melanoma diagnosis among Latino patients; health system challenges remain. ja.ma/4aYmJHP

This JAMA Clinical Insights outlines the clinical characteristics, diagnostic approach, and therapeutic strategies for managing scarring alopecias. ja.ma/3KIpjaq

Monthly vixarelimab led to rapid and sustained improvement in pruritus and lesion severity for adults with #PrurigoNodularis, with no serious drug-related adverse events reported. ja.ma/4pOaUJ4

Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events. ja.ma/4rV9dLc

In a clinic-based survey, patients demonstrated variable understanding of skin cancer–related terminology, with only 64.2% correctly identifying "clear margins" and 21.6% understanding "dysplastic nevus." ja.ma/4oQnmGP

A man in his 50s developed broad-spectrum abnormal localized photosensitivity syndrome, presenting as recurrent sun-induced, site-specific erythematous plaques confirmed by targeted phototesting. ja.ma/4pXv5nk

Acne prevalence among transmasculine patients ranged from 29.6% to 61.9% depending on methodology. 📌 This scoping review aims to summarize current literature for prevalence and factors associated with acne in transmasculine patients. ja.ma/4q7bBwS

💬 Editor's Note: Botulinum toxin injections appear safe and highly effective for acute digital ischemia and ulcers, particularly in systemic sclerosis and autoimmune vasculopathies, with minimal adverse events reported. ja.ma/4pXxsXh

Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events. ja.ma/4iNU4Hf

Although polarized dermatoscopes yielded more reportable images and fewer quality issues, a lower-cost, ambient-light, nonpolarized dermatoscope provided comparable clinical utility at a fraction of the cost. ja.ma/3M0EXOE

Autoantibody profiles, particularly antinuclear antibodies, showed higher positivity in classic dermatomyositis (DM) than clinically amyopathic DM. ja.ma/4olQXYr

In Sézary syndrome, detectable minimal residual disease at remission via high-throughput sequencing is linked to greater relapse risk. ja.ma/4p7hnyi

In patients with #psoriatic #arthritis, combination targeted therapy does not significantly increase the risk of serious or opportunistic infections compared to standard therapy. ja.ma/3M1Vy4z

This case report describes a woman in her 30s with porcelain-white discoloration of all nails, which persisted under pressure, and a GJA1 mutation. ja.ma/4prvTRa

A woman in her 50s presented with a nodular lesion on her left cheek. MRI revealed a well-defined, hypervascular, solid tumor located within the subcutaneous tissue with no evidence of invasion into adjacent structures. What is your diagnosis? ja.ma/3XjbQbM