A 6-month lifestyle-focused text-messaging intervention in adults with #Psoriasis improved patient activation, diet, physical activity, and medication adherence, but did not significantly change lipid levels, glycemic control, or disease severity. ja.ma/4u7Bizt

#GLP-1 receptor agonists show evidence of reducing #Psoriasis severity and systemic inflammation in patients with #obesity or #diabetes, with a favorable safety profile and compatibility with standard therapies. ja.ma/42wsvLq

Among 24,949 US patients with #Vitiligo, one-third were untreated after diagnosis and most treatments, primarily topical corticosteroids or calcineurin inhibitors, were of short duration, highlighting variable real-world management. ja.ma/48SW3GF

Among Boston neighborhoods, #HidradenitisSuppurativa clustered in areas with higher obesity, air pollution, heat, and proportions of Black residents, supporting a role for place-based factors in disease risk. ja.ma/48NHbtg

In PEDSnet hospitals, Black children had high #AtopicDermatitis and #HidradenitisSuppurativa frequencies yet consistently lower outpatient dermatology care use compared with other racial and ethnic groups. ja.ma/4eH91Lz

📄 This case report describes a previously healthy man in his 40s who presented with a 2-day history of asymptomatic rash, prior to which he experienced fever. ja.ma/49voc6O

This case report describes mogamulizumab-associated Kaposi sarcoma in 2 patients with primary cutaneous T-cell lymphomas. 📄Read the full report: ja.ma/4diWmgq

Among 24,949 US patients with #Vitiligo, one-third were untreated after diagnosis and most treatments, primarily topical corticosteroids or calcineurin inhibitors, were of short duration, highlighting variable real-world management. ja.ma/49yiykq

Anifrolumab treatment in #LupusErythematosus was associated with significant reductions in systemic and cutaneous disease activity, while SIGLEC-1 expression decreased alongside clinical improvement. ja.ma/3QYytC9

In PEDSnet hospitals, Black children had high #AtopicDermatitis and #HidradenitisSuppurativa frequencies yet consistently lower outpatient dermatology care use compared with other racial and ethnic groups. ja.ma/3QUrCtx

Among displaced persons at Mexico-US border humanitarian relief camps, infectious and inflammatory skin diseases were frequently diagnosed, especially in children and areas with overcrowding. ja.ma/4n6SDpG

This Review from the NPF Medical Board provides an evidence-informed narrative synthesis & practical considerations to introduce dermatologists to glucagon-like peptide-1 (#GLP1) receptor agonists for treatment of #psoriasis with metabolic comorbidities. ja.ma/49bgm28

Biologic therapy adherence, discontinuation, and selection varied across racial and ethnic groups in Medicaid patients with #Psoriasis, pointing to disparities that affect long-term management and outcomes. ja.ma/4cY4txP

A man in his 50s presented with a 4-mo history of pruritic, verrucous lesions on the right lower leg. What is your diagnosis? Take the Clinical Challenge: ja.ma/4n4DaGs

A man in his 60s undergoing #radiotherapy for prostate #cancer presented to the dermatology clinic with a 1-week history of a tender, pruritic rash to the trunk and extremities. What is your diagnosis? ja.ma/4cZ90zM

📃 This case report describes 2 patients with lichen sclerosus whose symptoms improved with glucagon-like peptide-1 receptor (#GLP-1) agonists. ja.ma/3Pd3jGG

This case report describes a woman in her 20s with hereditary leiomyomatosis and renal cell carcinoma. 📄 Read the full report: ja.ma/4ej5u5O

This Review from the NPF Medical Board provides an evidence-informed narrative synthesis & practical considerations to introduce dermatologists to glucagon-like peptide-1 (#GLP1) receptor agonists for treatment of #psoriasis with metabolic comorbidities. ja.ma/4w5Ulfa

In adults with necrobiosis lipoidica, PCS499, an oral deuterated pentoxifylline analog, was well tolerated and demonstrated clinical improvement, especially in ulcerated disease, supporting further evaluation in controlled studies. ja.ma/4t8DOo6

Encouraging use of lower-priced #sunscreens and sun protective clothing may help reduce the financial burden and support adherence to recommended skin protection behaviors. ja.ma/429SFDA

In adults with necrobiosis lipoidica, PCS499, an oral deuterated pentoxifylline analog, was well tolerated and demonstrated clinical improvement, especially in ulcerated disease, supporting further evaluation in controlled studies. ja.ma/3RazHdz

In high-risk cutaneous squamous cell carcinoma, ultrasonography and CT detected baseline nodal metastases more accurately than physical examination, but both modalities performed poorly in immunosuppressed patients. ja.ma/3OQm4PY

Progress toward the 2030 Sustainable Development Goals for skin-related neglected tropical diseases is insufficient globally, with widening regional inequalities and only a few countries on track for target achievement. ja.ma/4cM1ZlM

#AI-assisted dermoscopy matched or exceeded dermatologist performance for #Melanoma detection in prospective studies, but broader clinical validation is needed for routine use. ja.ma/3Q6IFYR

Bimekizumab provided rapid and sustained improvements in symptoms and quality of life for patients with moderate to severe #PlaquePsoriasis, with benefits maintained through 3 years. ja.ma/4d3SaRB

Dupilumab significantly reduced itch and hives severity in anti–immunoglobulin E–naive patients with chronic spontaneous urticaria uncontrolled by H1-antihistamines, with early and sustained improvements seen through week 24. ja.ma/4vM0zkb

New international consensus classifies #Vitiligo severity with expanded clinical and psychosocial criteria and standardizes relapse as renewed depigmentation of once repigmented skin. ja.ma/4cGUEnS

A multi-phase qualitative study developed a staged patient decision aid for #AtopicDermatitis systemic treatment that balances simple patient-focused content and clinician-desired detail, supporting shared decision-making in adults. ja.ma/4vEFIix

💬Editorial: Imaging-based nodal assessment improves subclinical metastasis detection in cutaneous squamous cell carcinoma, yet evidence supporting a survival benefit remains limited, indicating further research is needed for surveillance strategies. ja.ma/4ttGk9n

In high-risk cutaneous squamous cell carcinoma, ultrasonography and CT detected baseline nodal metastases more accurately than physical examination, but both modalities performed poorly in immunosuppressed patients. ja.ma/4sOcECE

💬 Editorial: Efforts to unify remission criteria in #AtopicDermatitis through clinician and patient measures highlight progress for research and guidelines, yet require further evaluation for feasibility and patient relevance. ja.ma/4mH9AXF

This case report analyzes 2 cases of older adults with chronic paronychia whose final diagnosis was osteomyelitis. ja.ma/3Oq4d2n

Access to an #AI-powered tool improved layperson accuracy in naming #SkinConcerns compared with traditional search, but did not increase accuracy of next-step decisions. ja.ma/4mEUuSw

Access to an #AI-powered tool improved layperson accuracy in naming #SkinConcerns compared with traditional search, but did not increase accuracy of next-step decisions. ja.ma/4muIMK9

#AI-assisted dermoscopy matched or exceeded dermatologist performance for #Melanoma detection in prospective studies, but broader clinical validation is needed for routine use. ja.ma/4c89N0T

Access to an #AI-powered tool improved layperson accuracy in naming #SkinConcerns compared with traditional search, but did not increase accuracy of next-step decisions. ja.ma/3QbO29k

New international consensus classifies #Vitiligo severity with expanded clinical and psychosocial criteria and standardizes relapse as renewed depigmentation of once repigmented skin. ja.ma/4sojxdH

Among more than 780 000 children in Denmark and England, #AtopicDermatitis was not linked to poorer academic performance on national exams regardless of disease phenotype or socioeconomic background. ja.ma/4sWyepu

#Sunscreen is essential for preventing sun damage, premature aging, & #SkinCancer. This JAMA Dermatology Patient Page provides a concise, dermatologist-approved guide to help you make the most of your sunscreen. ja.ma/4mgfsXJ

A man in his 70s was admitted with a symptomatic impending rupture of a thoracic aortic aneurysm, followed by reticulate erythematous to violaceous macules that appeared on the dorsal & plantar surfaces of both feet. Take the Clinical Challenge: ja.ma/4tBSgVY

A man in his 70s was admitted with a symptomatic impending rupture of a thoracic aortic aneurysm, followed by reticulate erythematous to violaceous macules that appeared on the dorsal & plantar surfaces of both feet. Take the Clinical Challenge: ja.ma/4tBfQT7

#PediatricDermatology care for racially minoritized families was impeded by factors such as unfamiliarity with dermatology, language barriers, long wait times, and lack of representation, but facilitated by parental advocacy and clinician communication. ja.ma/4czIRZm

Among more than 780 000 children in Denmark and England, #AtopicDermatitis was not linked to poorer academic performance on national exams regardless of disease phenotype or socioeconomic background. ja.ma/4sWyepu

#AI-assisted dermoscopy matched or exceeded dermatologist performance for #Melanoma detection in prospective studies, but broader clinical validation is needed for routine use. ja.ma/4c4dwy5

New international consensus classifies #Vitiligo severity with expanded clinical and psychosocial criteria and standardizes relapse as renewed depigmentation of once repigmented skin. ja.ma/3PPKtWg

This case report describes well-circumscribed, yellow-brown atrophic plaques on the legs that were rimmed by erythema and scale. ja.ma/41enuGJ

Among patients with chronic pruritus, sleep problems contributed more to daily functional impairment and were most significant in pruriceptive itch. ja.ma/4v6u3Jj

#CutaneousSquamousCellCarcinoma in Asian organ transplant recipients and immunocompetent patients featured distinct distributions of 65 #HPV genotypes, with B-HPV showing the greatest site overlap. ja.ma/4sUwf5a

📄 This case report describes large areas of erythema on the face, chest, and back with relatively clear boundaries and swollen hands with scattered skin-colored papules and nodules. ja.ma/41tiG0t

A clinical prediction model for #PemphigusVulgaris using hoarseness, dysphagia, and disease severity accurately predicted deep laryngeal involvement and may help guide laryngoscopy decisions. ja.ma/418ZSU2