(@leaolab.bsky.social)

Check out our group’s just-published paper in @NatureCommun: a macrocyclase with a built-in kinase domain that can phosphorylate peptides during RiPP biosynthesis and be swapped into other pathways 🧬 @ciimar.bsky.social @BlueBio4Future www.nature.com/articles/s41...

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Phosphorylation of peptides by a kinase domain in cyanobactin pathways - Nature Communications Phosphorylation is a key protein modification but rare in natural product biosynthesis. Here, authors discover cyanobacterial pathways that encode a kinase domain, leading to the production of phospho... https://www.nature.com/articles/s41467-025-65184-2