@rachelkarchin.bsky.social
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Excited to share new joint publication with the Tychele Turner lab at WashU now published in Cell Genomics! We do a proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancers and find some interesting differences!
tinyurl.com/2p9j559n
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Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer - PubMed
Prior studies examining genomic variants suggest that some proteins contribute to both neurodevelopmental disorders (NDDs) and cancer. While there are several potential etiologies, here, we hypothesiz...
https://pubmed.ncbi.nlm.nih.gov/40073865/
7 months ago
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bsky.app/profile/did:...
add a skeleton here at some point
7 months ago
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Karchin Lab at Johns Hopkins is excited to announce a postdoctoral position focused on developing innovative methods in computational immuno-oncology. Great opportunity if you are passionate about advancing cancer immunotherapy and bioinformatics. Learn more/apply:
karchinlab.org/join-us/
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Join us โ Karchin Lab
https://tinyurl.com/25ehczwb
7 months ago
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The Karchin Lab at Johns Hopkins is excited to announce a postdoctoral position focused on developing innovative methods in computational immuno-oncology. A great opportunity for researchers passionate about advancing cancer immunotherapy and bioinformatics. Learn more/apply:
tinyurl.com/25ehczwb
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LinkedIn
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https://lnkd.in/ehEwbKPn
7 months ago
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The Karchin Lab at Johns Hopkins is excited to announce a postdoctoral position focused on developing innovative methods in computational immuno-oncology. A great opportunity for researchers passionate about advancing cancer immunotherapy and bioinformatics. Learn more/apply here:
lnkd.in/ehEwbKPn
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LinkedIn
This link will take you to a page thatโs not on LinkedIn
https://lnkd.in/ehEwbKPn
7 months ago
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stevensalzberg.substack.com/p/the-pointl...
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The pointless destruction of the world's leading scientific and medical research system
No one benefits from this
https://stevensalzberg.substack.com/p/the-pointless-destruction-of-the
8 months ago
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Check out the new preprint from
karchinlab.org
tinyurl.com/vxm7b6n6
about a new computational method to estimate the cellular prevalence of somatic structural variants in tumors from bulk DNAseq.
#genomics
#cancer
#bioinformatics
#tumor_evolution
@hopkinsengineer.bsky.social
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SVCFit: Inferring structural variant cellular fraction in tumors
Many tumors evolve through cellular mutation and selection, where subpopulations of cells (subclones) with shared ancestry compete for dominance. Introduction of next generation sequencing enables sub...
https://tinyurl.com/vxm7b6n6
8 months ago
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