@drbenweitz.bsky.social
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A lifetime of reading books, writing, and learning languages could be one of the best ways to keep your mind sharp and prevent Alzheimer's disease, according to a new study in the journal Neurology:
www.neurology.org/doi/10.1212/...
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NeurologyĀ® Journals
https://www.neurology.org/doi/10.1212/WNL.0000000000214677
about 3 hours ago
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A common bacteria Chlamydia pneumoniae that causes pneumonia and sinus infections can get into the brain and be an inflammatory trigger for Alzheimer's Disease
www.nature.com/articles/s41...
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Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimerās disease retina - Nature Communications
This study detects Chlamydia pneumoniae in human retina and brain, increasing with AD severity. Retinal pathogen load with Aβ42 may predict AD stage. In models, infection drives Aβ deposition and NLRP...
https://www.nature.com/articles/s41467-026-68580-4
about 13 hours ago
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The sugar alcohol, Erythritol, damages cells lining blood vessels to reduce nitric oxide and ramping up endothelin-1, which leads to constriction of blood vessels in the brain, raising the risk of ischemic stroke.
www.sciencealert.com/common-sweet...
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Common Sweetener May Damage Critical Brain Barrier, Risking Stroke
Found in everything from protein bars to energy drinks, erythritol has long been considered a safe alternative to sugar.
https://www.sciencealert.com/common-sweetener-may-damage-critical-brain-barrier-risking-stroke
1 day ago
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Food preservatives increase the risk of cancer
www.bmj.com/content/392/...
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Intake of food additive preservatives and incidence of cancer: results from the NutriNet-SantƩ prospective cohort
Objective To investigate the association between intake of food additive preservatives and cancer incidence in a large prospective cohort. Design Prospective cohort. Setting French NutriNet-SantƩ co...
https://www.bmj.com/content/392/bmj-2025-084917
4 days ago
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Skeletal muscle improves vascular health and endothelial function by buffering metabolic stress through glucose disposal, insulin sensitivity, and releases myokines that protect vascular health
www.nature.com/articles/s44...
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Muscle mass as a resilence factor for endothelial health in obesity - npj Metabolic Health and Disease
npj Metabolic Health and Disease - Muscle mass as a resilence factor for endothelial health in obesity
https://www.nature.com/articles/s44324-025-00096-9
4 days ago
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How to use a Functional Medicine approach to help patients with psychiatric disorders with Dr. James Greenblatt
youtu.be/ksfYW1t7xNo?...
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Finally Hopeful for Fixing Depression with Dr. James Greenblatt: Rational Wellness Podcast 449
YouTube video by Ben Weitz, DC
https://youtu.be/ksfYW1t7xNo?si=WnIbw_538h8Q5dbQ
5 days ago
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How to use a Functional Medicine approach to help patients with psychiatric disorders with Dr. James Greenblatt
youtu.be/ksfYW1t7xNo?...
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Finally Hopeful for Fixing Depression with Dr. James Greenblatt: Rational Wellness Podcast 449
YouTube video by Ben Weitz, DC
https://youtu.be/ksfYW1t7xNo?si=WnIbw_538h8Q5dbQ
5 days ago
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Brain HQ brain training game found to be effective at preventing dementia
www.yahoo.com/news/article...
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Brain train game may help protect against dementia for up to 20 years
A large, long-term study found that playing a brain training video game may help protect the brain against dementia for decades.
https://www.yahoo.com/news/articles/brain-train-game-may-help-130000488.html
6 days ago
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Higher levels of omega 3 in blood were associated with lower risk of early onset dementia
www.clinicalnutritionjournal.com/article/S026...
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Blood omega-3 is inversely related to risk of early-onset dementia
Early-onset dementia (EOD, defined as diagnosis < age 65) imposes a high socio-economic burden. It is less prevalent and less investigated than late-onset dementia (LOD). Observational data indicate t...
https://www.clinicalnutritionjournal.com/article/S0261-5614(25)00338-3/abstract
7 days ago
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The Teen Health Revolution from The Holistic Kids
youtu.be/YK33iSQEwhw?...
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The Teen Health Revolution with The Holistic Kids: Rational Wellness Podcast 448
YouTube video by Ben Weitz, DC
https://youtu.be/YK33iSQEwhw?si=1gMicKW34bth7FNl
12 days ago
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New research explains why statin medications sometimes (10%) cause muscle pain
www.sciencealert.com/painful-side...
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Painful Side Effect of Statins Explained After Decades of Mystery
Around 10 percent of people who take statins to lower cholesterol experience mysterious muscle pains, causing many to discontinue these potentially life-saving medicines.
https://www.sciencealert.com/painful-side-effect-of-statins-explained-after-decades-of-mystery
12 days ago
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Prenatal exposure to BPS (often substituted for BPA) and methylparabens may be associated with behavioural difficulties in young children
www.medscape.com/viewarticle/...
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Does Prenatal Phenol Exposure Affect Early Child Behaviour?
Researchers report links between third-trimester exposure to endocrine disruptors and higher behavioural risk scores in early childhood.
https://www.medscape.com/viewarticle/does-prenatal-phenol-exposure-affect-early-child-behaviour-2025a100109g
13 days ago
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Older patients have increased risk with GLP-1s, including loss of muscle and bone, as well as dehydration, GI effects, hypoglycemia, and neurologic changes
www.medscape.com/viewarticle/...
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Older Patients Have Specific Risks for GLP-1 Use
Patients older than 65 years are candidates for GLP use, but you should know the individual risks.
https://www.medscape.com/viewarticle/older-patients-have-specific-risks-glp-1-use-2026a10003bb
13 days ago
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People who consume higher levels of nitrate from vegetables have a lower risk of developing dementia, while those who get more nitrate and nitrite from animal-based foods, processed meats, and drinking water face a higher risk of dementia
scitechdaily.com/nitrate-in-d...
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Nitrate in Drinking Water May Raise Dementia Risk, Study Warns
A large, decades-long population study suggests that the relationship between diet and dementia may hinge on subtle chemical differences in everyday foods and water.
https://scitechdaily.com/nitrate-in-drinking-water-may-raise-dementia-risk-study-warns/
14 days ago
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Inflammation (HsCRP) is now being emphasized as a modifiable risk factor for Cardiovascular disease by the American College of Cardiology, but we have been targeting inflammation in the Functional Medicine world for decades.
www.medscape.com/viewarticle/...
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Inflammation Is No Longer Theoretical CV Risk
Systemic inflammation has been elevated to a modifiable cardiovascular risk factor requiring assessment, monitoring, and modification, based on consensus recommendations.
https://www.medscape.com/viewarticle/inflammation-joins-list-modifiable-cardiovascular-risk-2026a10002ke
14 days ago
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There is the rare risk of a severe and possibly fatal form of acute pancreatitis with GLP-1 agonist drugs
www.medscape.com/viewarticle/...
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MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs
The MHRA has updated safety information for GLP-1 weight-loss and diabetes drugs after rare reports of necrotising and fatal pancreatitis.
https://www.medscape.com/viewarticle/mhra-warns-rare-severe-pancreatitis-glp-1-drugs-2026a100032y?ecd=WNL_trdalrt_pos1_260201_etid8073128&uac=202247CR&impID=8073128
15 days ago
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PFOA (a forever chemical) common in the US environment may reduce fertility.
scitechdaily.com/common-envir...
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Common Environmental Chemical May Sabotage Early Pregnancy, New Study Warns
New research suggests that exposure to a common āforever chemicalā may interfere with the earliest stages of pregnancy. A new animal study suggests that perfluorooctanoic acid (PFOA), a chemical used ...
https://scitechdaily.com/common-environmental-chemical-may-sabotage-early-pregnancy-new-study-warns/
15 days ago
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Alpha Lipolic acid 600 mg/day beneficial for patients with Heart Failure
www.sciencedirect.com/science/arti...
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Efficacy of Alpha-Lipoic Acid in Patients With Ischemic Heart Failure: A Double-Blind, Randomized, Placebo-Controlled Study
https://www.sciencedirect.com/science/article/pii/S2213177925008285
16 days ago
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A newly discovered peptide--CAQK--may be able to help Traumatic Brain Injury and promote brain health
link.springer.com/article/10.1...
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A neuroprotective tetrapeptide for treatment of acute traumatic brain injury - EMBO Molecular Medicine
Traumatic brain injury (TBI) is a major clinical problem because of the high incidence and the severity of the subsequent sequelae. Despite extensive efforts, there are no therapeutic drugs clinically...
https://link.springer.com/article/10.1038/s44321-025-00312-5
17 days ago
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Dark Chocolate contains Theobromine that slows Biological Aging.
www.sciencedaily.com/releases/202...
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Scientists find dark chocolate ingredient that slows aging
Scientists have uncovered a surprising link between dark chocolate and slower aging. A natural cocoa compound called theobromine was found in higher levels among people who appeared biologically young...
https://www.sciencedaily.com/releases/2025/12/251212022249.htm
17 days ago
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Eating blueberries promotes better cardiometabolic health
www.sciencedaily.com/releases/202...
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New review finds wild blueberries support heart and gut health
A sweeping scientific review highlights wild blueberries as a standout food for cardiometabolic health. The strongest evidence shows improvements in blood vessel function, with encouraging signs for b...
https://www.sciencedaily.com/releases/2026/01/260127112125.htm
18 days ago
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Solutions for Postpartum Depletion with Dr. Lauren Davis
youtu.be/0CmZStNi6cA?...
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Solutions for Postpartum Depletion with Dr. Lauren Davis: Rational Wellness Podcast 447
YouTube video by Ben Weitz, DC
https://youtu.be/0CmZStNi6cA?si=2Wg1pkwnivaY6Q2N
20 days ago
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Roasted coffee contains three newly identified diterpine esters that inhibit α-glucosidase, an enzyme that plays a central role in breaking down carbohydrates during digestion, which benefits diabetics
www.sciencedaily.com/releases/202...
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Newly discovered coffee compounds beat diabetes drug in lab tests
Roasted coffee may do more than wake you upāit could help control blood sugar. Researchers discovered several new coffee compounds that inhibit α-glucosidase, a key enzyme linked to type 2 diabetes. S...
https://www.sciencedaily.com/releases/2026/01/260110211224.htm
21 days ago
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Thiamine, vitamin B1, may play a significant role in modulating gut motility
www.sciencedaily.com/releases/202...
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A common vitamin could influence bathroom frequency
Scientists studying genetic data from over a quarter million people have uncovered new clues about what controls how fast the gut moves. They identified multiple DNA regions linked to bowel movement f...
https://www.sciencedaily.com/releases/2026/01/260122074659.htm
21 days ago
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A new analysis shows that individuals w/the highest plasma omegaā3 levels were the least likely to develop AFIB and fish oil supplement users had no increase in Atrial Fibrillation, contradicting a previous report linking such use with a higher risk of AF
www.ahajournals.org/doi/full/10....
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Associations Between Plasma Omegaā3 and Fish Oil Use With Risk of Atrial Fibrillation in the UK Biobank | Journal of the American Heart Association
https://www.ahajournals.org/doi/full/10.1161/JAHA.125.043031
22 days ago
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Artificial sweeteners are associated with increased cognitive decline
www.neurology.org/doi/10.1212/...
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Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline | Neurology
Background and ObjectivesConsumption of low- and no-calorie sweeteners (LNCSs) has been associated with adverse health outcomes. However, little is known about the association between consumption of L...
https://www.neurology.org/doi/10.1212/WNL.0000000000214023
22 days ago
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Methionine, the amino acid often maligned as a cancer generator, is beneficial for immune function and kidney protection:
www.cell.com/cell-metabol...
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Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines
Troha et al. found that dietary methionine enhances kidney filtration and promotes urinary excretion of inflammatory cytokines during infection. By improving cytokine clearance, this pathway mitigates...
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00542-X
24 days ago
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In this episode of Rational Wellness, Dr. Ben Weitz speaks with Dr. Sanjeev Goel about the science and clinical strategies behind longevity and biohacking.
youtu.be/m763vMk3hh4?...
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Advanced Biohacking & Longevity Strategies Clinicians Should Know with Dr. Sanjeev Goel: RWP 446
YouTube video by Ben Weitz, DC
https://youtu.be/m763vMk3hh4?si=cU-U1HE_kGViNzBs
26 days ago
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Eat more nuts! Regular consumption of nuts is associated with lower Cardiovascular Disease and Ischemic Heart Disease mortality.
jn.nutrition.org/article/S002...
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Nut Consumption and Risk of Cardiovascular Disease and Ischemic Heart Disease Mortality: The Adventist Health Study 2
Cardiovascular disease (CVD) and ischemic heart disease (IHD) are leading causes of mortality worldwide. Nut consumption has been associated with reduced risk.
https://jn.nutrition.org/article/S0022-3166(25)00641-8/abstract
28 days ago
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A low FODMAP diet improves patients with IBS with diarrhea and also improves mast cell activation and leaky gut.
www.gastrojournal.org/article/S001...
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Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet Improves Colonic Barrier Function and Mast Cell Activation in Patients With Diarrhea-Predominant Irritable Bowel Synd...
A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols strengthened the gut barrier and stabilized activated mast cells seen in patients with diarrhea-predominant infl...
https://www.gastrojournal.org/article/S0016-5085(25)05771-3/fulltext
30 days ago
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Both fish oil supplementation and omega 3 levels are associated with significantly less anxiety and depression
jn.nutrition.org/article/S002...
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Associations of Plasma Omega-3 Fatty Acid Levels and Reported Fish Oil Supplement Use with Depression and Anxiety: A Cross-Sectional Analysis from the United Kingdom Biobank
The role that marine omega-3 (nā3) polyunsaturated fatty acids (PUFAs) may play in reducing the risk for developing depression and/or anxiety is unclear.
https://jn.nutrition.org/article/S0022-3166(25)00680-7/fulltext
about 1 month ago
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Higher intake of natto and vitamin K are associated with decreased risk of AFIB in women.
jn.nutrition.org/article/S002...
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Association of Soy Foods, Soybeans, Isoflavones, and Vitamin K Intake and the Risk of Atrial Fibrillation: A Prospective Cohort Study
Recent findings have revealed that high soy food consumption may prevent cardiovascular diseases. However, their role in preventing atrial fibrillation (AF) remains unexplored.
https://jn.nutrition.org/article/S0022-3166(25)00718-7/abstract
about 1 month ago
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Curious about the connection between autoimmune conditions and gut health? Tune in to the newest episode of the Rational Wellness Podcast with special guest Dr. Taylor Krick. Learn more about managing chronic health conditions.
youtu.be/OeMNgny0btA?...
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Functional Medicine Approach to Autoimmunity with Dr. Taylor Krick: Rational Wellness Podcast 445
YouTube video by Ben Weitz, DC
https://youtu.be/OeMNgny0btA?si=HncbdD5cWi0e5qLF
about 1 month ago
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Maternal nonanemic iron deficiency in early pregnancy was associated with low iron status at birth and worse language and motor outcomes at 2 y of age.
jn.nutrition.org/.../S0022-31...
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https://jn.nutrition.org/.../S0022-3166(25)00706-0/fulltext
about 1 month ago
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47% of homes in the US contain mold
www.medscape.com/s/viewarticl...
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A Hidden Health Crisis: Mold Growth in Homes
An estimated 47% of residential buildings in the US contain mold or dampness.
https://www.medscape.com/s/viewarticle/hidden-health-crisis-following-natural-disasters-mold-growth-2025a1000wnb
about 1 month ago
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Older Americans (~60%) are quitting GLP-1 drugs within a year due to costs, GI symptoms and the loss of muscle.
kffhealthnews.org/news/article...
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Older Americans Quit Weight Loss Drugs in Droves - KFF Health News
In some studies, half of patients stopped taking GLP-1s within a year despite the benefits, citing the expense and side effects.
https://kffhealthnews.org/news/article/glp1-older-americans-quitting-weight-loss-drugs/
about 1 month ago
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Functional Medicine Lab Interpretation with Reed Davis
youtu.be/RuJCyaPo6Bk?...
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Functional Medicine Lab Interpretation with Reed Davis: Rational Wellness Podcast 444
YouTube video by Ben Weitz, DC
https://youtu.be/RuJCyaPo6Bk?si=EBfrFWEyCBsRbjoB
about 1 month ago
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Here is a meta-analysis of the benefits of a ketogenic diet for cognitive function of patients with Alzheimer's Disease
www.sciencedirect.com/science/arti...
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Effects of ketogenic diet on cognitive function of patients with Alzheimer's disease: a systematic review and meta-analysis
Ketogenic diets (KD) have shown remarkable effects in many disease areas. It has been demonstrated in numerous animal experiments that KD is effectiveā¦
https://www.sciencedirect.com/science/article/pii/S1279770724003932
about 1 month ago
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Those who consumed the widest diversity of dietary flavonoids had a 6ā20% significantly lower risk of all-cause mortality and incidence of cardiovascular disease, type 2 diabetes, cancer, respiratory disease and neurodegenerative disease
www.nature.com/articles/s43...
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High diversity of dietary flavonoid intake is associated with a lower risk of all-cause mortality and major chronic diseases - Nature Food
The intake of polyphenolic compounds is part of a healthy diet, but the contribution of a diversity of flavonoids to health outcomes remains unknown. This study shows that participants in the UK Bioba...
https://www.nature.com/articles/s43016-025-01176-1
about 2 months ago
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Exploring Advances in Spine Surgery with Dr. Amir Vokshoor
youtu.be/OkPpWz9sge4?...
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Spinal Disc Replacement Surgery with Dr. Amir Vokshoor: Rational Wellness Podcast 443
YouTube video by Ben Weitz, DC
https://youtu.be/OkPpWz9sge4?si=YRknV9hkscizMZVP
about 2 months ago
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Depression and Anxiety are both linked to major adverse cardiac events, likely through stress-related neural activity
www.ahajournals.org/doi/10.1161/...
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American Heart Association Journals
https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.124.017706
about 2 months ago
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Heavy alcohol use is associated with worse cardiovascular health, but the American Heart Association is continuing the debate whether light drinking can be part of a healthy lifestyle, despite recent evidence that any alcohol is bad
www.ahajournals.org/doi/10.1161/...
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Alcohol Use and Cardiovascular Disease: A Scientific Statement From the American Heart Association | Circulation
Alcohol is one of the most commonly consumed substances in the world, exhibiting complex relationships with multiple aspects of cardiovascular health and disease. The majority of the research on the t...
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001341
about 2 months ago
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At Cedars-Sinai Medical Center in Los Angeles, an unusually high number of people had heart attacks or acute pulmonary illnesses during the 90 days after the wildfire onset, with a 46% increase in acute myocardial infarction
www.jacc.org/doi/10.1016/...
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Emergency Encounters for Illness During and After the Los Angeles Wildfires:
https://www.jacc.org/doi/10.1016/j.jacc.2025.10.079
about 2 months ago
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Melatonin and Pycnogenol both help to lower Myeloperoxidase (MPO), a marker of arterial inflammation that we measure to assess CVD risk
www.ahajournals.org/doi/10.1161/...
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Reduction of Myeloperoxidase Activity by Melatonin and Pycnogenol May Contribute to their Blood Pressure Lowering Effect | Hypertension
https://www.ahajournals.org/doi/10.1161/hypertensionaha.110.158170
about 2 months ago
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New research indicates how the COVID vaccine can result in myocarditis and how genistein might help to blunt this effect (by inhibiting C-X-C motif chemokine ligand 10 (CXCL10) and interferon-γ (IFN-γ), which were identified as the drivers of the inflammation)
www.science.org/doi/10.1126/...
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Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
Preclinical models of SARS-CoV-2 vaccination revealed a targetable CXCL10āIFN-γ axis that drives cytokine-induced cardiac injury.
https://www.science.org/doi/10.1126/scitranslmed.adq0143
about 2 months ago
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Dietary Supplementation with Six Percent Blueberries Attenuates Neurodegeneration and Motor Deficits in rats with Parkinson'sĀ disease
jn.nutrition.org/article/S002...
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Dietary Supplementation with Six Percent Blueberries (Vaccinium corymbosum L.) Attenuates Neurodegeneration and Motor Deficits in a Parkinson's Disease Model
Parkinson disease (PD) is a progressive neurodegenerative disorder associated with oxidative stress and neuroinflammation. Blueberries (Vaccinium corymbosum L.), rich in polyphenols and anthocyanins, ...
https://jn.nutrition.org/article/S0022-3166(25)00634-0/abstract
about 2 months ago
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An excellent interview with Integrative Pediatrician, Dr. Pejman Katiraei about Neurodegenerative Disorders in Children
youtu.be/SpEB6w7HcpU?...
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Dr. Pejman Katiraei on Neurodevelopment Disorders in Children: Rational Wellness Podcast 442
YouTube video by Ben Weitz, DC
https://youtu.be/SpEB6w7HcpU?si=-T9YA-uCTfcDlpJf
about 2 months ago
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When pregnant women drink water that comes from wells contaminated with PFAS, the risks of low birth weight, preterm birth and infant mortality substantially increase
theconversation.com/pfas-in-preg...
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PFAS in pregnant womenās drinking water puts their babies at higher risk, study finds
An innovative study mapped preterm births, low birth weights and infant mortality to municipal water wells downstream from PFAS-contaminated sites. The results show the high cost of PFAS harm.
https://theconversation.com/pfas-in-pregnant-womens-drinking-water-puts-their-babies-at-higher-risk-study-finds-270051
about 2 months ago
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Accumulating evidence indicates that C-Reactive protein (HS-CRP) (inflammation marker) is a more predictive marker for heart disease than LDL cholesterol
theconversation.com/how-c-reacti...
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How C-reactive protein outpaced ābadā cholesterol as leading heart disease risk marker
C-reactive protein ā a marker of inflammation ā is as easily measured with blood work in a doctorās office as cholesterol.
https://theconversation.com/how-c-reactive-protein-outpaced-bad-cholesterol-as-leading-heart-disease-risk-marker-271143?utm_content=buffer2a9e0&utm_medium=social&utm_source=bluesky&utm_campaign=buffer
about 2 months ago
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Ultraprocessed food intake linked to early onset of precancerous colorectal polyps in women
jamanetwork.com/journals/jam...
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Ultraprocessed Foods Linked to Signs of Early-Onset Colorectal Cancer in Women
Women with high ultraprocessed food (UPF) intake may be at elevated risk of certain precancerous colorectal polyps, research findings published in JAMA Oncology suggest.
https://jamanetwork.com/journals/jama/fullarticle/2842580
about 2 months ago
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