Wouter Moolenaar (@wouterhm.bsky.social)

Four decades after their discovery, lipid-anchored proteins still hold mysteries. Our Opinion article sheds light on how these proteins are released from their anchors, and how this process rewires signaling networks and impacts cell fate: Trends in Cell Biology www.cell.com/trends/cell-...

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Unlocking the signaling potential of GPI-anchored proteins through lipolytic cleavage Glycosylphosphatidylinositol (GPI)-anchored proteins (APs) regulate numerous biological processes through interaction with signaling effectors at the cell surface. As a unique feature, GPI-APs can be ... https://www.cell.com/trends/cell-biology/fulltext/S0962-8924%2824%2900278-2