Haering Lab
@haeringlab.bsky.social
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Lab Homepage: go.uniwue.de/bcz Impressum:
https://www.uni-wuerzburg.de/sonstiges/impressum/
Our new preprint in collaboration with
@meisterpeterf.bsky.social
uncovers the molecular basis for condensin recruitment to X chromosomes in C. elegans and reveals atomic-level details of a previously unknown auto-inhibited state of condensin.
www.biorxiv.org/cgi/content/short/2026.03.13.711519v1
27 days ago
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Congratuations to our PhD Student
@gurumoorthya.bsky.social
on winning the Poster Award for his work on gene regulation by DNA loop extrusion and phase separation at the CNIO-CaixaResearch Frontiers Meeting on "Machines acting on DNA and RNA, a molecular mechanistic perspective"!
10 months ago
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In our latest mini review, Toni Valdes and I discuss the potential role(s) of DNA superhelicity in the organization of chromosomes by SMC protein complexes, covering classical biochemistry experiments to recent single-molecule biophysics studies.
doi.org/10.1042/BST2...
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Adding a twist to the loops: the role of DNA superhelicity in the organization of chromosomes by SMC protein complexes
Structural maintenance of chromosomes (SMC) protein complexes, including cohesin, condensin, and the Smc5/6 complex, are integral to various processes in chromosome biology. Despite their distinct rol...
https://doi.org/10.1042/BST20240650
over 1 year ago
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