NCI CIP-Net
@nci-cipnet.org
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Official BlueSky account of the NCI Cancer Immunoprevention Network (CIP-Net). www.nci-cipnet.org
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The Cancer Immunoprevention Network (CIP-Net), established by the National Cancer Institute (NCI), advances the understanding of fundamental immunoprevention mechanisms, drives the discovery of novel strategies, and supports the preclinical development and testing of new interventions
nci-cipnet.org
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CIP-Net
http://nci-cipnet.org
2 months ago
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New
#CIPNetPublication
: Drs. Haval Shirwan, Esma Yolcu and team dissect how SA-4-1BBL, a CD137 agonist, drives balanced and durable immune activation to prevent cancer, using advanced bioinformatics and transcriptomic analyses. The work is published in Biomolecules MDPI
www.mdpi.com/2218-273X/16...
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https://www.mdpi.com/2218-273X/16/2/252
8 days ago
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🧬CIP-Net Project Spotlight UG3CA290300, led by Dr. Shadmehr Demehri, is investigating how the immune system can protect normal breast tissue and intercept cancer before it starts in people with inherited BRCA mutations 👉Learn more:
www.nci-cipnet.org/en/members/u...
8 days ago
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🧬 CIP-Net Project Spotlight UG3CA290454 is developing a preventive cancer vaccine for people with inherited BRCA1/2 mutations, using chimeric RNA-derived neoantigens to stop breast cancer before it forms. 👉Learn more on the CIP-Net website:
www.nci-cipnet.org/en/members/u...
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CIP-Net
https://www.nci-cipnet.org/en/members/ug3ca290454/
9 days ago
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NCI CIP-Net
The Cancer Immunoprevention Network (CIP-Net), established by the National Cancer Institute (NCI), advances the understanding of fundamental immunoprevention mechanisms, drives the discovery of novel strategies, and supports the preclinical development and testing of new interventions
nci-cipnet.org
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CIP-Net
http://nci-cipnet.org
2 months ago
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At today’s NCI Computational Oncology Working Group meeting, Dr. Roland Dunbrack of Fox Chase Cancer Center presented his work on structural bioinformatics and AlphaFold modeling of the human kinome and its interactions.
26 days ago
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#CIPNetPublication
in Nature Cancer by Dr. Madhav Dhodapkar: The MyCheckpoint randomized trial reports durable clinical responses in multiple myeloma following TIGIT or LAG3 immune checkpoint blockade, with distinct pathway-specific immune correlates for each arm.
pubmed.ncbi.nlm.nih.gov/39187595/
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Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial - PubMed
Persons with myeloma were randomized to receive an anti-TIGIT (T cell immunoreceptor) or anti-LAG3 (lymphocyte activation gene) antibody followed by combination with pomalidomide and dexamethasone ( NCT04150965 ). Primary and secondary endpoints were safety and efficacy, respectively. Therapy was we …
https://pubmed.ncbi.nlm.nih.gov/39187595/
about 2 months ago
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#CIPNetSCMeeting
2 months ago
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The Cancer Immunoprevention Network (CIP-Net), established by the National Cancer Institute (NCI), advances the understanding of fundamental immunoprevention mechanisms, drives the discovery of novel strategies, and supports the preclinical development and testing of new interventions
nci-cipnet.org
loading . . .
CIP-Net
http://nci-cipnet.org
2 months ago
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