Mike Coston (@fla-medic.bsky.social)

Asymptomatic, acute and persistent COVID-19 symptom changes over the course of three infections Data from a UK healthcare worker cohort published in 2024 examined how signs and symptoms of COVID-19 changed after 1, 2, or 3 SARS-CoV-2 lab-confirmed infections. Those with no symptoms through to those whose symptoms persisted for >12 weeks recalled their experience, and the cohort included vaccinated and unvaccinated people and spanned the presence of different virus variants. Humans not modelling The SARS-CoV-2 Immunity and Reinfection EvaluatioN (SIREN) study is a large cohort study of UK healthcare workers. The participants were tested each fortnight by SARS-CoV-2 PCR and regular antibody testing (serology). https://virologydownunder.com/asymptomatic-acute-and-persistent-covid-19-symptom-changes-over-the-course-of-three-infections/