What do you do when grants are cancelled, faculty searches are frozen, and the ability to do the science you believe in is slipping out of reach? I wrote an essay. On efforts to solve aging with reprogramming, the primacy of the epigenome, and the path to rewriting our future:

maybe we just need more positive visions of what the future could look like if we develop mirror life

nothing cooler than watching a friend literally turn science fiction into reality it's been awe-inspiring to watch @andrewcpayne.bsky.social and co build E11 Bio and prove that the FRO model can produce amazing, unique science also expansion + molecular barcoding <3

Excited to see our T-cell exhaustion preprint published! This work is led by Tristan Tay and collaborators at AstraZeneca. See the sub-thread (reformatted for bluesky) originally composed and posted by the newly minted Dr. Tay www.cell.com/cell-reports...

to shy posters, a reminder that you can literally just post about science you think is cool & if you're looking for the next single-cell or spatial, I suspect single-molecule sequencing is about to blow up 👀 www.cell.com/cell/fulltex... www.biorxiv.org/content/10.1... www.nature.com/articles/s41...

just a pic of my dog maple taking "be one with nature" a little too literally

when you temporarily have more followers than your PI (anyway @jbuenrostro.bsky.social is here now)

New episode! This time on The Climate Biotech Podcast, Homeworld Collective co-founders Dan Goodwin and Paul Reginato sit down with the legendary George Church—a pioneer in genomics and synthetic biology. Spotify: open.spotify.com/episode/6LfF... Apple Podcasts: podcasts.apple.com/us/podcast/e...

who knew it would be easier to get everyone to switch social media platforms than getting them to use hg38

Leonid Mirny and I wrote this for all interested in chromosomes: "The chromosome folding problem and how cells solve it" www.cell.com/action/showP...

wake up babe, new george church skincare routine just dropped www.biorxiv.org/content/10.1...

seems like a fun game for all the scientists excited by the move but also mourning having to rebuild their following (it me) I once made a meme to explain all of the drama surrounding the word "epigenetics" - to my horror, it is now used in at least several PhD classes

Just published: "Multiplexed expansion revealing for imaging multiprotein nanostructures in healthy and diseased brain", led by Jinyoung Kang and Margaret Schroeder! multiExR enables antibody staining of >20 proteins in a sample w/registration error down to 25 nm. www.nature.com/articles/s41...

7 years ago, I met a junior fellow named Jason Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (Ajay Labade, Caroline Comenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/