We just wrapped up the 7th Molecular & Cellular Pharmacology Retreat in the Florida Keys, and the energy was incredible. Under the theme “Colab in the Cays,” scientists from 15+ labs shared 53 talks across two days, with every single participant presenting their work.

PIONEER: A Periplasmic Display Platform for Synthetic Biology-Based Screening of Genetically Encoded Protein Regulators - Journal of Biological Chemistry www.jbc.org/article/S002...

Support my running of the 5K! Funds go directory to research labs @SylvesterCancer: dolphinscancerchallenge.com/participant/...

"A recent study employing parallel mutagenesis of titratable residues in GPR68 identified a conserved triad of buried acidic residues in proton sensing GPCRs. Here, too, neutral mutations to these sites shift pH50 but do not abolish proton-mediated receptor activation."

I have received many requests for this, so I am sharing it here. I hope it works (password: 7i+fFdMG) @Pap_Corps @SylvesterCancer @danIsomLab: tinyurl.com/Pap-Corps-EC...

The combined single-day profit of the top 25 US companies would fully fund the annual $3.2B NIGMS budget.

Happy Thanksgiving from Miami.

Yay Defne! news.med.miami.edu/can-a-diabet...

In my excitement for his visit, I forgot to get a selfie with Henrik. This will have to do 😂

Our small review on using yeast synthetic biology to advance human GPCR biology and pharmacology. tinyurl.com/2p88y72h

What a wonderful scientific retreat for UM Pharmacology this week @bakerscayresort. Time is running out to join our faculty and enjoy the Keys and science for yourself! bit.ly/3GAxDD6

Looking for cool colleagues! Recruiting at assistant and associate levels. I am happy to answer any questions. www.nature.com/naturecareer...

Chicagoland.

SUP on Lake Tahoe today:

Happy to be among this fine assembly of protonators: https://www.biophysics.org/2023tahoe-protonreaction/program/daily-schedule

Wow, SoCal feeling SoFlo.

PIEZO1 action up close: https://www.nature.com/articles/s41586-023-06427-4

Cool, but SUPER TINY proteins: https://www.nature.com/articles/s41586-023-06328-6

STING may be a proton channel: https://www.science.org/doi/10.1126/science.adf8974?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed