New article: Correction: Circulating nitric oxide pathway metabolites in heart failure with preserved ejection fraction: a sex-stratified cross-sectional analysis: https://link.springer.com/article/10.1186/s13293-026-00944-3

New article: "This study aimed to investigate the organizational role of neonatal estradiol (E2) in early-life sex-patterning of microglia for disease onset and progression," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00948-z

New article: Authors note that "there is a gap in understanding the predominance of males with idiopathic pulmonary fibrosis," leading to their research focus. Read more: https://link.springer.com/article/10.1186/s13293-026-00942-5

New article: "The objective of this study is to evaluate how sex and gender are labeled, operationalized, and aligned with underlying source data in clinical decision-support tools," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00946-1

#DYK? 30% of couples experiencing #infertility are diagnosed with unexplained infertility. For clinicians, it's time to know more about diagnosing & discussing infertility: https://swhr.org/resources/clinician-resource-guide-to-fertility-health-care/#DYK?#infertility#SWHRtalksFertility #InfertilityAwarenessMonth

New article: In study highlights, authors write "Prenatal BPA exposure was associated with altered alternative splicing in the cerebellum, including mis-splicing of the exon encoding the SAP domain of Ccar1 in males." Read more: https://link.springer.com/article/10.1186/s13293-026-00941-6

New article: "Since protein levels are downstream products of gene expression, proteomics data can be crucial to understand etiology of sex-differences in lipids metabolism," authors write in their introduction. Read more: https://link.springer.com/article/10.1186/s13293-026-00934-5

New article: "The substantial overlap of metabolic profiles between women and men showed no distinct patterns of circulating metabolites linked to endothelial function in patients with HFpEF," authors write in their conclusion. Read more: https://link.springer.com/article/10.1186/s13293-026-00940-7

New article: "We investigated how different NR5A1 variants affect downstream gene regulation and contribute to DSD pathogenesis," authors write about their research. Read more: https://link.springer.com/article/10.1186/s13293-026-00939-0

New article: "Where we are born, grow, live, work and age have been shown to differentially impact life expectancy between high- and low-income countries by 33 years," authors write in this article: https://link.springer.com/article/10.1186/s13293-026-00936-3

New article: "Small differences between females and males in cognitive abilities have been consistently reported, but the factors underlying these sex differences remain unclear," authors begin with. Read the full article: https://link.springer.com/article/10.1186/s13293-026-00929-2

New article: "Our findings revealed that early-life stress caused long-term changes that differed between males and females, influencing how they deal with stress and respond to alcohol," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00937-2

New article: Study results shows circulating CD38 (an NADase implicated in aging and metabolic stress) may be related to broader cardiometabolic-renal stress context. Read the results to learn more: https://link.springer.com/article/10.1186/s13293-026-00924-7

New article: In this large-scale functional neuroimaging investigation article, authors "found that face-selective visual cortical regions in the inferior temporal visual cortex were more activated by viewing faces in females." Read more: https://link.springer.com/article/10.1186/s13293-026-00933-6

New article: The article provides a systematic review and meta-analysis of PRISMA guidelines "to quantify sex-specific cerebral palsy risk across gestational age." https://link.springer.com/article/10.1186/s13293-026-00935-4

New article: Authors write, "this review integrates current knowledge on sex-related differences in Aortic stenosis... to propose a hypothesis-driven framework on how gut microbiota may contribute to sex-specific differences in AS." https://link.springer.com/article/10.1186/s13293-026-00932-7

New article: "Early and sex-specific amygdaloid proteome dysregulation in Alzheimer’s Disease highlights the consideration of a deliberate stratification by sex in future research," authors write. Read the results further: https://link.springer.com/article/10.1186/s13293-026-00930-9

New article: "Recent advances in sex differences in the nervous system and behavior lay a foundation for future studies to reveal sex-specific mechanisms in behavior and nervous system disorders," authors write in this article: https://link.springer.com/article/10.1186/s13293-026-00931-8

New article: "These findings indicate that adolescent social stress induces sex-dependent behavioral and neurochemical responses," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00928-3

New article: Findings of this study "may have important implications in understanding sex differences for the neural mechanisms promoting hypertension," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00922-9

New article: The research aims to "investigate whether sex differences induce changes in the expression of genes in response to cardiac circulatory death conditions, including ischemia-reperfusion injury." Read more: https://link.springer.com/article/10.1186/s13293-026-00915-8

New article: "Our findings highlight the necessity of sex-stratified analysis in cardiovascular biomarker research," authors write in their conclusion. Read more: https://link.springer.com/article/10.1186/s13293-026-00926-5

New article: "Our results suggest that dysregulation of hypoxia-related pathways in Glioblastoma plays a female-specific role in resistance to treatment and overall outcomes," authors write. Read the full study and results: https://link.springer.com/article/10.1186/s13293-026-00927-4

New article: Authors state that "the molecular basis underlying these sex-specific differences remains insufficiently understood," prompting further research on the topic. Read more: https://link.springer.com/article/10.1186/s13293-026-00925-6

New article: This study found that "elevated total testosterone and sex hormone-binding globulin levels are associated with higher risks of chronic liver disease -related outcomes, particularly in males." Read more: https://link.springer.com/article/10.1186/s13293-026-00923-8

New article: "Emerging research reveals that sex differences in immunity arise from layered interactions between sex chromosome dosage, hormone signalling across the lifespan, and epigenetic regulation," authors write: https://link.springer.com/article/10.1186/s13293-026-00881-1

New article: "This study examined sex and age differences in the prevalence of modifiable dementia risk factors and their associations with cognition," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00908-7

New article: Authors here found "#breastfeeding in infancy confers a long-term protective effect against MASH and adverse liver outcomes in women, but not in men." Read the results: https://link.springer.com/article/10.1186/s13293-026-00919-4

New article: "Recognizing these interconnected and sex-specific influences is critical for advancing precision prevention and treatment strategies across the Cardiovascular–kidney–metabolic syndrome spectrum," authors write. Read more: https://link.springer.com/article/10.1186/s13293-026-00878-w

New article: Authors here aimed to probe the relationship between stress coping, sex, and stress-linked behavioral outcomes." Read their results to learn more: https://link.springer.com/article/10.1186/s13293-026-00918-5

New article: "Findings reveal the sex-biased effects of estrogen and estrogen-mimetic compounds in traditional culture media, underscoring a current gap in considering sex as a biological variable in cell therapy," authors write: https://link.springer.com/article/10.1186/s13293-026-00921-w

New article: This article reviews existing studies that suggest "female patients may have a higher overall risk of postoperative recurrence than male patients." Read the review to learn more: https://link.springer.com/article/10.1186/s13293-026-00914-9

New article: Authors here "provide examples of empirical research programs that demonstrate the benefit of these frameworks in the context of sex/gender research." Read more: https://link.springer.com/article/10.1186/s13293-026-00920-x

New article: Authors "trained sex-specific machine learning algorithms using routine clinical data to evaluate sex-specific learning patterns and diagnostic performance." Read the report: https://link.springer.com/article/10.1186/s13293-026-00917-6

May 12 was SexDifferencesAwarenessDay. "This day affords us a moment to reflect on the significant impact sex differences research has had on health care, medicine, and scientific discovery." https://communities.springernature.com/posts/celebrating-sex-differences-to-improve-health-for-all

For the latest on #SexDifferences research, check out the Biology of Sex Differences journal at bsd.biomedcentral.com