Recent review clarifies the prevalence of undifferentiated autoinflammatory diseases (uAIDs) and shows that IL-1-targeted biologics achieve remission in 70% of patients. Fever, arthralgia, and abdominal pain are common symptoms. #Pediatrics #BiologicsTherapy link.springer.com/article/10.1...

New small-molecule therapies show promise for pediatric inflammatory bowel disease (pIBD), with early trials reporting reduced symptoms. Long-term safety remains unclear. Review highlights the need for age-specific treatments and more research. #Pediatrics #IBD link.springer.com/article/10.1...

A key pillar of next-gen immunotherapy? Safer than CAR-T, with lower CRS/neurotoxicity risk and true “off-the-shelf” potential, CAR-NK therapy shows promising efficacy across cancers, autoimmune & infectious diseases. #Pediatrics #Immunotherapy link.springer.com/article/10.1...

Since 2024, key milestones in pediatric lung health include breakthroughs in asthma genetics, respiratory syncytial virus vaccine development, and AI diagnostics. Advancements tackle rising asthma, post-COVID surges, antibiotic resistance. #Pediatrics #Asthma link.springer.com/article/10.1...

New consensus on Respiratory Syncytial Virus prevention: Vaccinating pregnant women and using nirsevimab in infants significantly reduce severe infections and hospitalizations, aiming to improve infant health in Latin America. #Pediatrics #Vaccine #InfantHealth link.springer.com/article/10.1...

Special Issue | Treatment of Pediatric Sleep Disturbances: Insights on managing bedtime problems and night wakings, concerns over melatonin use, and updates on sleep-related movement disorders—with evidence-based care for kids’ sleep. #Pediatrics #SleepScience link.springer.com/journal/1251...

Special Issue | Identifying Pediatric Sleep Disturbances: the revised Chinese Children’s Sleep Habits Questionnaire (CSHQ-CH-R) showed acceptable to good psychometric properties, offering a more accurate version suitable for clinical use. #Pediatrics #SleepHealth link.springer.com/article/10.1...

Special Issue | Pediatric sleep disturbances: New insights reveal how prenatal support boosts child happiness and sleep quality, while sleep duration, bedtime routines, screen time, and mindfulness impact mental health. #Pediatrics #ChildHealth #SleepScience link.springer.com/article/10.1...

Struggling with bedtime battles? Our latest issue features a special section on children’s sleep health, covering topics from sleep disorders, sleep hygiene, to the impact of sleep on child development, improving sleep quality for better overall health. link.springer.com/journal/1251...

MMP-7 is a biomarker for biliary atresia, a severe liver disease in infants, and is released upon epithelial injury. A new AI model combining ultrasound and serum MMP-7 achieves 98.2% sensitivity and 93.1% specificity in diagnosing biliary atresia! #Pediatrics link.springer.com/article/10.1...

Thinking of getting a pet for your child? New study shows that cat ownership at age 4-5 is linked to more mental problems at 7-8, but always having pets like hamsters, fish, or turtles was protective against internalizing problems. #Pediatrics #Pet #MentalHealth link.springer.com/article/10.1...

Ketogenic diet (KD) and Modified Atkins Diet (MAD) greatly reduce seizures in drug-resistant epilepsy, especially in kids. KD is more effective for ≥90% seizure reduction, while MAD works better for ≥50% reduction. #Pediatrics #Epilepsy #DietaryTherapies link.springer.com/article/10.1...

Pertussis is rising globally, impacting children and adults. China faces erythromycin-resistant strains, challenging treatment. New expert consensus offers a diagnosis & treatment flowchart, clarifying criteria & high-risk case definitions. #Pediatrics #Pertussis link.springer.com/article/10.1...

Expert consensus, based on 64 studies, provides comprehensive exercise recommendations for children with asthma, covering safety, benefits, and key factors, emphasizing tailored plans and multidisciplinary collaboration. #Pediatrics #Asthma #Exercise link.springer.com/article/10.1...

A multidisciplinary expert panel developed disease-based long-term follow-up care plans for childhood cancer survivors in China, including a centralized database to track treatment summaries and late effects. #Pediatrics#ChildhoodCancerSurvivors link.springer.com/article/10.1...

Adolescents with social anxiety disorder exhibit distinct metabolic profiles. A total of 46 significantly altered metabolites were identified, mainly enriched in amino acid and energy metabolism pathways. #Pediatrics #SocialAnxiety #AdolescentHealth link.springer.com/article/10.1...

rTMS works fast for youth depression. New meta-analysis of 16 trials shows significant symptom relief in just 2 weeks, with even greater effect at 4 weeks. A promising treatment for the young suffering from depression. #Pediatrics #Depression #YouthHealth #Therapy link.springer.com/article/10.1...

Recent review shows that type I interferon is overactive in kids with lupus, driving inflammation, highlighting key genes, biomarkers, and new treatment options like IFN blockers & JAK inhibitors. #Meded #SoMe4PedSurg #Pediatrics #PediatricSLE #Interferon link.springer.com/article/10.1...

A retrospective cohort study of 19,656 pregnancies linked maternal conditions to congenital kidney and urinary tract anomalies, and predictive models were developed. #Pediatrics #KidneyAnomalies #PregnancyHealth link.springer.com/article/10.1...

Study analyzed 2082 patients to identify clinical differences between pediatric and adult Behçet’s syndrome, revealing five clinical phenotypes in kids. Insights aid tailored treatment. #Pediatrics #BehçetsSyndrome #PediatricVasculitis link.springer.com/article/10.1...

Rare pediatric case: An 8-year-old with persistent cough & wheezing turned out to have lymphatic plastic bronchitis after expectorating gelatinous casts. #Pediatrics #PlasticBronchitis link.springer.com/article/10.1...

🌟 Protecting Future Mothers, Safeguarding Lifelong Health Join global experts at the 2025 West Lake International Pediatric Adolescent Gynaecology Conference to advance adolescent reproductive health. Free registration! 📅 Nov 28–30 | 📍 Hangzhou, China 🔗 m.qihe.live/meeting/68C1...

Review on childhood obesity — Analyzing 161 studies on genetic causes, this review highlights the leptin–melanocortin pathway and shows that genetic factors account for 7% of extreme obesity cases. #Meded #SoMe4PedSurg #Pediatrics #Obesity #Leptin link.springer.com/article/10.1...

Editorial series on optimizing respiratory disease management. Each piece explores a unique angle: updated asthma therapies, vitamin D’s role in asthma, and the impact of human parainfluenza virus. #Meded #SoMe4PedSurg #Pediatrics #Asthma #Infection

Updated pediatric syncope guidelines cover diagnosis, treatment, and non-pharmacological therapies, emphasizing postural tests and follow-up. Essential for managing syncope in kids and teens. #Meded #SoMe4PedSurg #Pediatrics #Syncope #Guideline link.springer.com/article/10.1...

Review of 63 studies (2008-2024) shows radiomics and AI enhance MRI analysis for pediatric brain tumors, improving diagnosis and treatment. Collaboration with data experts crucial for clinical applications. #Meded #SoMe4PedSurg #Pediatrics #Neuroradiology link.springer.com/article/10.1...

Despite being life-saving, #ECMO for neonates carries neuro risks. Data from a review article show: 50% exhibit brain injury, 18-23% have seizures within 24h, and bleeding occurs in 27-60% of procedures. #Meded #SoMe4PedSurg #Pediatrics link.springer.com/article/10.1...

3D imaging tracks facial profile changes in infants with Robin sequence. Specialized treatment shows promise for catch-up growth of the mandible in the first year. #Meded #SoMe4PedSurg #Pediatrics #RobinSequence #FacialProfile #MandibularGrowth #Infant link.springer.com/article/10.1...

Meta-analysis reveals rising prevalence of nonalcoholic fatty liver disease (NAFLD): 13% globally, 47% in obese children. Higher in males. Urgent need for more research as childhood obesity increases. #Meded #SoMe4PedSurg #Pediatrics #NAFLD link.springer.com/article/10.1...

The first global consensus on pediatric macrolide-resistant M. pneumoniae (MRMP), offering evidence-based guidance on diagnosis, early detection, and treatment. A must-read for pediatric clinicians. #Meded #SoMe4PedSurg #Pediatrics #Infection #Pneumonia link.springer.com/article/10.1...

New study on CRE infections in pediatric liver transplants! Researchers analyzed data from 2017-2023 to identify risk factors and build prediction models. Exciting findings could help protect young patients! #Meded#SoMe4PedSurg #Pediatrics #Liver link.springer.com/article/10.1...

Youth suicide rates declined but remain high, with boys and Southeast Asia most affected, and COVID-19 likely increasing risks, according to a new study. Targeted interventions and support systems needed! #WorldSuicidePreventionDay #Meded #SoMe4PedSurg #Pediatrics link.springer.com/article/10.1...

Scientists are exploring new biomarkers and AI to improve early detection and prediction of acute kidney injury (AKI) in children, aiming to enhance clinical management and outcomes. #Meded #SoMe4PedSurg #Pediatrics #kidney #AI link.springer.com/article/10.1...

Researchers developed a low-cost method to screen newborns for thalassemia and hemoglobin disorders, aiding early treatment and improving health outcomes！ #Meded #SoMe4PedSurg #Pediatrics #Thalassemia #Hemoglobin link.springer.com/article/10.1...

The proposed entity, MIHRD, defines early obesity-induced disruption of the HPG axis, emphasizing neuroinflammation as a central driver of reproductive dysfunction. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #Endocrinology #ReproductiveHealth link.springer.com/article/10.1...

New Chinese guidelines give recommendations for rituximab in pediatric steroid-sensitive nephrotic syndrome, covering timing, dosage, frequency, co-medications, and follow-up. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #NephroticSyndrome #Rituximab #TICMED25 link.springer.com/article/10.1...

Pediatric anemia persists in low-SDI Asian countries due to poverty, malnutrition, and poor healthcare. Targeted nutrition, disease control, and global support are vital. #SoMe4PedSurg #MedEd #Pediatrics #Anemia #GlobalHealth #Nutrition #TIC2025 link.springer.com/article/10.1...

Global data show low smoking cessation and attempts among adolescents 13–15. School education boosts quit attempts and success; reducing secondhand smoke aids cessation. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #TobaccoControl #Smoking #TICMED25 link.springer.com/article/10.1...

From 1990–2021, cancer mortality in youth dropped, but disparities persist by income, type, and region. Rising colorectal cancer signals urgent need for action. #SoMe4PedSurg #MedEd #Cancer #GlobalHealth #PublicHealth #Pediatrics #YoungAdults #TICMED25 link.springer.com/article/10.1...

The PRIDE tool for Chinese children used item response theory with robust statistical methods to enhance accuracy and reliability in developmental delay screening. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #DevelopmentalDelay #ScreeningTool #TICMED25 link.springer.com/article/10.1...

Using ETCOc to guide phototherapy decisions in near-term and term infants reduced phototherapy rates within 7 days without increasing severe hyperbilirubinemia. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #Hyperbilirubinemia #ETCOc #TICMED25 link.springer.com/article/10.1...

Single-dose intrathecal GC101 gene therapy was generally safe and showed motor function improvement or stabilization in children with type II and III spinal muscular atrophy. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #GeneTherapy #SpinalMuscularAtrophy #TICMED25

Suboptimal vitamin D levels are consistently associated with increased asthma risk, severity, and poorer control in children, though causality remains to be confirmed. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #VitaminD #Asthma #TICMED25 link.springer.com/article/10.1...

Most neonates with suspected hypoxic–ischemic encephalopathy show brain injury, but other causes exist and diagnosis evolves over time. #SoMe4PedSurg #MedEd #Pediatrics #NeonatalEncephalopathy #HypoxicIschemicEncephalopathy #Neuroprotection #MultiOmics #TICMED25 link.springer.com/article/10.1...

During the COVID-19 pandemic, healthy children had reduced nasal microbiota diversity, which may affect respiratory health. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #COVID19 #Microbiota #RespiratoryHealth #InfectionRisk #TICMED25 link.springer.com/article/10.1...

Early limitations in play mediate links between chronic physical illness and later mental health problems in children, highlighting the role of active social engagement. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #MentalHealth #ChildDevelopment #TICMED25 link.springer.com/article/10.1...

Smartphone bans in schools: Intended to help, but evidence shows they don't improve grades/wellbeing—and may cause harm. Time to rethink? #SoMe4PedSurg #MedEd #MedX #Pediatrics #PublicHealth #SmartphoneBans #Policy #Technology #SocialMedia #TICMED25 link.springer.com/article/10.1...

This study developed and validated a real-time prediction of acute kidney injury risk in hospitalized pediatric patients, demonstrating its clinical potential for early prevention. #SoMe4PedSurg #MedEd #Pediatrics #Kidney #MachineLearning #Prediction #TICMED25 link.springer.com/article/10.1...

Nusinersen treatment is not only effective but also sustainable in improving and maintaining the motor function of Chinese children with later-onset spinal muscular atrophy. #SoMe4PedSurg #MedEd #MedX #Pediatrics #Efficacy #Nusinersen #SMA #MotorFunction #TICMED25 link.springer.com/article/10.1...

Serum bile acid profiles may help identify central precocious puberty in girls, offering a less invasive diagnostic approach. #Meded #SoMe4PedSurg #Pediatrics #PublicHealth #CentralPrecociousPuberty #BileAcids #Biomarkers #Metabolomics link.springer.com/article/10.1...