MKRN3 mutations spark early puberty, yet its loss in Prader-Willi syndrome delays it—new study traces this paradox to 18,000+ epigenetic switches, revealing how one gene drives opposite outcomes. #Pediatrics #PrecociousPuberty #Prader-WilliSyndrome link.springer.com/article/10.1...

Kids entering obesity programs in spring lose less weight than other seasons—summer holidays disrupt progress. 68% saw BMI drops at 6 months, but spring entry cut benefits. #Meded #SoMe4PedSurg #Pediatrics #ChildhoodObesity #SeasonalHealth link.springer.com/article/10.1...

Deep learning tools achieved >85% accuracy across 22 studies in diagnosing pediatric neurodevelopmental disorders, but key challenges in standardization and bias remain for clinical translation. #Pediatrics #AI #Neurodevelopment link.springer.com/article/10.1...

Can ultrasound help confirm brain death in children? Transcranial Doppler detects blood flow patterns and shows promise as a bedside tool for pediatric brain death determination. More research is needed to standardize its use. #Pediatrics #BrainDeath #Ultrasound link.springer.com/article/10.1...

Kids with complicated appendicitis: New review shows post-discharge oral antibiotics at home may not reduce infection risk. Routine use is not recommended due to a lack of clear benefit. #Pediatrics #Appendicitis #OralAntibiotics link.springer.com/article/10.1...

Clean Intermittent Catheterization (CIC) in kids: New guideline identifies safe bladder capacity, optimal catheterization frequency, and need for caregiver training. Standardizing care improves outcomes. #Pediatrics #Guideline #CIC #Urodynamic link.springer.com/article/10.1...

Cerebral palsy patients face hidden dangers from posterior drooling and saliva aspiration, impacting respiratory health. A scoping review found only 9.5% of studies focus on these issues. More research is needed. #Pediatrics #CerebralPalsy #RespiratoryHealth link.springer.com/article/10.1...

Recent review synthesizes current evidence to optimize standardized management of pediatric gastrointestinal bleeding (GIB). Timely endoscopy and early risk assessment improve outcomes and reduce complications. #Pediatrics #GIB #ClinicalManagement link.springer.com/article/10.1...

Two editorials, one theme: strengthening preparedness for future pandemics through lessons from major coronavirus outbreaks, and addressing pediatric thunderstorm asthma amid a changing climate—together framing emerging challenges in child respiratory health. #Pediatrics #Coronavirus #ClimateChange

Parenting practices around screen time may influence teen video game habits. More parental monitoring and limiting screen time reduce mature-rated game use and total gaming time. #Pediatrics #VideoGaming #Parenting link.springer.com/article/10.1...

🗣️ New @ucsfchildrens.bsky.social study in @world-j-pediatr.bsky.social! Certain media parenting practices associated with reduced teen #videogame use @ucsf-ihps.bsky.social 🔗 Read here: tinyurl.com/VGParent

Children with HIV face higher cancer risks. New study highlights the need for early antiretroviral therapy (ART) to reduce cancer incidence and improve outcomes in this vulnerable population. #Pediatrics #HIV #CancerRisk link.springer.com/article/10.1...

Survey shows 44.1% of Chinese adolescents have tried alcohol, with 11.2% drinking in the past month. Drinking often starts early, at age 13 or younger. Family gatherings are the main drinking occasion. #Pediatrics #AlcoholUse #Prevalence link.springer.com/article/10.1...

Type 1 diabetes presents differently in children versus later onset: early-onset features more pronounced islet impairment, whereas onset after age 10 brings more metabolic complications despite relatively preserved insulin production. #Pediatrics #Metabolism link.springer.com/article/10.1...

Combining knee radiomic scores with traditional methods can more accurately predict final height in girls after menarche, offering a promising new approach for growth assessments. #Pediatrics #GrowthPrediction #Radiomics link.springer.com/article/10.1...

Recent review clarifies the prevalence of undifferentiated autoinflammatory diseases (uAIDs) and shows that IL-1-targeted biologics achieve remission in 70% of patients. Fever, arthralgia, and abdominal pain are common symptoms. #Pediatrics #BiologicsTherapy link.springer.com/article/10.1...

New small-molecule therapies show promise for pediatric inflammatory bowel disease (pIBD), with early trials reporting reduced symptoms. Long-term safety remains unclear. Review highlights the need for age-specific treatments and more research. #Pediatrics #IBD link.springer.com/article/10.1...

A key pillar of next-gen immunotherapy? Safer than CAR-T, with lower CRS/neurotoxicity risk and true “off-the-shelf” potential, CAR-NK therapy shows promising efficacy across cancers, autoimmune & infectious diseases. #Pediatrics #Immunotherapy link.springer.com/article/10.1...

Since 2024, key milestones in pediatric lung health include breakthroughs in asthma genetics, respiratory syncytial virus vaccine development, and AI diagnostics. Advancements tackle rising asthma, post-COVID surges, antibiotic resistance. #Pediatrics #Asthma link.springer.com/article/10.1...

New consensus on Respiratory Syncytial Virus prevention: Vaccinating pregnant women and using nirsevimab in infants significantly reduce severe infections and hospitalizations, aiming to improve infant health in Latin America. #Pediatrics #Vaccine #InfantHealth link.springer.com/article/10.1...

Special Issue | Treatment of Pediatric Sleep Disturbances: Insights on managing bedtime problems and night wakings, concerns over melatonin use, and updates on sleep-related movement disorders—with evidence-based care for kids’ sleep. #Pediatrics #SleepScience link.springer.com/journal/1251...

Special Issue | Identifying Pediatric Sleep Disturbances: the revised Chinese Children’s Sleep Habits Questionnaire (CSHQ-CH-R) showed acceptable to good psychometric properties, offering a more accurate version suitable for clinical use. #Pediatrics #SleepHealth link.springer.com/article/10.1...

Special Issue | Pediatric sleep disturbances: New insights reveal how prenatal support boosts child happiness and sleep quality, while sleep duration, bedtime routines, screen time, and mindfulness impact mental health. #Pediatrics #ChildHealth #SleepScience link.springer.com/article/10.1...

Struggling with bedtime battles? Our latest issue features a special section on children’s sleep health, covering topics from sleep disorders, sleep hygiene, to the impact of sleep on child development, improving sleep quality for better overall health. link.springer.com/journal/1251...

MMP-7 is a biomarker for biliary atresia, a severe liver disease in infants, and is released upon epithelial injury. A new AI model combining ultrasound and serum MMP-7 achieves 98.2% sensitivity and 93.1% specificity in diagnosing biliary atresia! #Pediatrics link.springer.com/article/10.1...

Thinking of getting a pet for your child? New study shows that cat ownership at age 4-5 is linked to more mental problems at 7-8, but always having pets like hamsters, fish, or turtles was protective against internalizing problems. #Pediatrics #Pet #MentalHealth link.springer.com/article/10.1...

Ketogenic diet (KD) and Modified Atkins Diet (MAD) greatly reduce seizures in drug-resistant epilepsy, especially in kids. KD is more effective for ≥90% seizure reduction, while MAD works better for ≥50% reduction. #Pediatrics #Epilepsy #DietaryTherapies link.springer.com/article/10.1...

Pertussis is rising globally, impacting children and adults. China faces erythromycin-resistant strains, challenging treatment. New expert consensus offers a diagnosis & treatment flowchart, clarifying criteria & high-risk case definitions. #Pediatrics #Pertussis link.springer.com/article/10.1...

Expert consensus, based on 64 studies, provides comprehensive exercise recommendations for children with asthma, covering safety, benefits, and key factors, emphasizing tailored plans and multidisciplinary collaboration. #Pediatrics #Asthma #Exercise link.springer.com/article/10.1...

A multidisciplinary expert panel developed disease-based long-term follow-up care plans for childhood cancer survivors in China, including a centralized database to track treatment summaries and late effects. #Pediatrics#ChildhoodCancerSurvivors link.springer.com/article/10.1...

Adolescents with social anxiety disorder exhibit distinct metabolic profiles. A total of 46 significantly altered metabolites were identified, mainly enriched in amino acid and energy metabolism pathways. #Pediatrics #SocialAnxiety #AdolescentHealth link.springer.com/article/10.1...

rTMS works fast for youth depression. New meta-analysis of 16 trials shows significant symptom relief in just 2 weeks, with even greater effect at 4 weeks. A promising treatment for the young suffering from depression. #Pediatrics #Depression #YouthHealth #Therapy link.springer.com/article/10.1...

Recent review shows that type I interferon is overactive in kids with lupus, driving inflammation, highlighting key genes, biomarkers, and new treatment options like IFN blockers & JAK inhibitors. #Meded #SoMe4PedSurg #Pediatrics #PediatricSLE #Interferon link.springer.com/article/10.1...

A retrospective cohort study of 19,656 pregnancies linked maternal conditions to congenital kidney and urinary tract anomalies, and predictive models were developed. #Pediatrics #KidneyAnomalies #PregnancyHealth link.springer.com/article/10.1...

Study analyzed 2082 patients to identify clinical differences between pediatric and adult Behçet’s syndrome, revealing five clinical phenotypes in kids. Insights aid tailored treatment. #Pediatrics #BehçetsSyndrome #PediatricVasculitis link.springer.com/article/10.1...

Rare pediatric case: An 8-year-old with persistent cough & wheezing turned out to have lymphatic plastic bronchitis after expectorating gelatinous casts. #Pediatrics #PlasticBronchitis link.springer.com/article/10.1...

🌟 Protecting Future Mothers, Safeguarding Lifelong Health Join global experts at the 2025 West Lake International Pediatric Adolescent Gynaecology Conference to advance adolescent reproductive health. Free registration! 📅 Nov 28–30 | 📍 Hangzhou, China 🔗 m.qihe.live/meeting/68C1...

Review on childhood obesity — Analyzing 161 studies on genetic causes, this review highlights the leptin–melanocortin pathway and shows that genetic factors account for 7% of extreme obesity cases. #Meded #SoMe4PedSurg #Pediatrics #Obesity #Leptin link.springer.com/article/10.1...

Editorial series on optimizing respiratory disease management. Each piece explores a unique angle: updated asthma therapies, vitamin D’s role in asthma, and the impact of human parainfluenza virus. #Meded #SoMe4PedSurg #Pediatrics #Asthma #Infection

Updated pediatric syncope guidelines cover diagnosis, treatment, and non-pharmacological therapies, emphasizing postural tests and follow-up. Essential for managing syncope in kids and teens. #Meded #SoMe4PedSurg #Pediatrics #Syncope #Guideline link.springer.com/article/10.1...

Review of 63 studies (2008-2024) shows radiomics and AI enhance MRI analysis for pediatric brain tumors, improving diagnosis and treatment. Collaboration with data experts crucial for clinical applications. #Meded #SoMe4PedSurg #Pediatrics #Neuroradiology link.springer.com/article/10.1...

Despite being life-saving, #ECMO for neonates carries neuro risks. Data from a review article show: 50% exhibit brain injury, 18-23% have seizures within 24h, and bleeding occurs in 27-60% of procedures. #Meded #SoMe4PedSurg #Pediatrics link.springer.com/article/10.1...

3D imaging tracks facial profile changes in infants with Robin sequence. Specialized treatment shows promise for catch-up growth of the mandible in the first year. #Meded #SoMe4PedSurg #Pediatrics #RobinSequence #FacialProfile #MandibularGrowth #Infant link.springer.com/article/10.1...

Meta-analysis reveals rising prevalence of nonalcoholic fatty liver disease (NAFLD): 13% globally, 47% in obese children. Higher in males. Urgent need for more research as childhood obesity increases. #Meded #SoMe4PedSurg #Pediatrics #NAFLD link.springer.com/article/10.1...

The first global consensus on pediatric macrolide-resistant M. pneumoniae (MRMP), offering evidence-based guidance on diagnosis, early detection, and treatment. A must-read for pediatric clinicians. #Meded #SoMe4PedSurg #Pediatrics #Infection #Pneumonia link.springer.com/article/10.1...

New study on CRE infections in pediatric liver transplants! Researchers analyzed data from 2017-2023 to identify risk factors and build prediction models. Exciting findings could help protect young patients! #Meded#SoMe4PedSurg #Pediatrics #Liver link.springer.com/article/10.1...

Youth suicide rates declined but remain high, with boys and Southeast Asia most affected, and COVID-19 likely increasing risks, according to a new study. Targeted interventions and support systems needed! #WorldSuicidePreventionDay #Meded #SoMe4PedSurg #Pediatrics link.springer.com/article/10.1...

Scientists are exploring new biomarkers and AI to improve early detection and prediction of acute kidney injury (AKI) in children, aiming to enhance clinical management and outcomes. #Meded #SoMe4PedSurg #Pediatrics #kidney #AI link.springer.com/article/10.1...

Researchers developed a low-cost method to screen newborns for thalassemia and hemoglobin disorders, aiding early treatment and improving health outcomes！ #Meded #SoMe4PedSurg #Pediatrics #Thalassemia #Hemoglobin link.springer.com/article/10.1...

The proposed entity, MIHRD, defines early obesity-induced disruption of the HPG axis, emphasizing neuroinflammation as a central driver of reproductive dysfunction. #SoMe4PedSurg #MedEd #Pediatrics #PublicHealth #Endocrinology #ReproductiveHealth link.springer.com/article/10.1...