Went to basel last week for a Farewell Seminar for Patrick Matthias at the FMI. Really enjoyed meeting old alumni of Patrick’s lab. Enjoy your new adventure Patrick!!

Happy to share our last paper. We show that the inoculation of 4 commensal bacteria to chicks has both short- and long-term effects on immune response and microbiota composition and promoted the low-shedder phenotype thanks to a more fermentative microbiota. www.tandfonline.com/doi/full/10....

We are looking for a PhD candidate starting on the 01-10-2025. The project aims to understand how the host cells use copper and oxidative species to fight Salmonella infection and how this pathogen evades this antimicrobial response. SHORT DEADLINE ! 20-04-2025 jobs.inrae.fr/en/ot-25517

👀 Save the date....

First snow this year in Touraine, France at my workplace (it’s been a few years without I heard)! Cold 🥶 but so happy to see some snow ⛄️

Nice work from @laurenpalmer.bsky.social ! Showing once more the important link between zinc, inflammation and antimicrobial response, Here, Acinetobacter baumannii.

Perfect project for a post-doc! You will have access to a great set of data and we have already exciting hypotheses! Don’t hesitate to contact us.

Looking for PostDoc - Metabolism/Salmonella. We are looking for candidates with excellent knowledge in bioinformatics and bacterial physiology / microbial ecology. We will help the candidate to build a successful application for European grants such as EMBO and Marie Skłodowska-Curie Actions.

With all the new people, perhaps I should post an introduction. I am an immunologist identifying new antimicrobial responses in macrophages. My current research focuses on the use of metal ions (Zn & Cu) vs Salmonella infection. Always love to meet new faces and set up new collaborations. 🔬🦠

Very useful ! Thanks !

It’s out ! Our review on antibacterial responses in macrophages in @NatRevImmunol . We tried to cover as many pathways as we can, macrophages always astonish me by their immense arsenal. Very happy to have collaborated on that paper ! Version online FREE: rdcu.be/dUlUZ

Good News ! We are looking for a PhD student to work on understanding the role of zinc in the host response to Salmonella. How macrophage use the Zn? How Salmonella resist Zn and can escape this antimicrobial weapon? Deadline 31.05.24 to start 01-10-2024. jobs.inrae.fr/en/ot-21883

Super stoke with the publication of this work ! Amazing job from @KaustavDasGupt8 and James to carry out the work ! How the heavy metal zinc is linked to antimicrobial response in CF patients. doi.org/10.1073/pnas...

Music Brings People Together 🎶 A nice project from one of my friends to establish his awesome Music School close to Tours, France. Every little donation is worth a lot for them ! www.kisskissbankbank.com/fr/projects/...

Last few days before deadline!

Biology is never simple ! I’m happy to share our new publication on the role of HDAC6 on inflammasome. We used several methods (KO mouse, inhibitors, DARPIN…) to show that HDAC6 is NOT always driving the inflammasome and is context-dependent. DOI:https://doi.org/10.1016/j.jbc.2024.105638

Good news ! I’m looking for a post-doc (1 year ½ contract) to join our MiMoSa team at the @INRAE_VDL . Host-pathogen interaction project on understanding the dynamic of Zn and Cu during Salmonella infection. Deadline: Feb 11th, 2024. jobs.inrae.fr/en/ot-19561

I finally made it onto BlueSky ! I'm rebuilding my network slowly. I will try to update regularly my profile with (mostly) science while setting up my research at the INRAE ! Macrophages, Salmonella, metal ions (zinc) & mitochondria