João Ferreira Fernandes (@immjoao.bsky.social)

Happy to share that our review on the structural biology of T-cell surface proteins is out in Immunological Reviews. Here we describe the ways in which crystal structures and cryo-EM have informed our understanding of receptor behaviour and T-cell biology. onlinelibrary.wiley.com/doi/full/10....

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The Structural Biology of T‐Cell Antigen Detection at Close Contacts T cells physically interrogate their targets using tiny membrane protrusions called microvilli, forming junctions ~400 nm in diameter and ~ 15 nm deep, referred to as “close contacts”. These contacts... https://onlinelibrary.wiley.com/doi/full/10.1111/imr.70014

11 months ago