Jay Hesselberth
@jayhesselberth.bsky.social
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📥 570
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RNA technologies. hesselberthlab.org
Excited to see this collaborative work with Olivia Rissland's lab finally out. We found lots of 2A peptides and an entirely new 2A class.
www.cell.com/cell-reports...
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Systematic identification and characterization of eukaryotic and viral 2A peptide-bond-skipping sequences
Rao et al. identified thousands of previously unknown 2A peptides across both viruses and eukaryotes using an HMMER analysis. The authors further identified a unique class of 2A peptides, class B, who...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00593-5
5 months ago
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Just released an update of an R data package for NIH funding data from 1985-2024.
github.com/rnabioco/nih...
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GitHub - rnabioco/nihexporter: An R data package for NIH EXPORTER data
An R data package for NIH EXPORTER data. Contribute to rnabioco/nihexporter development by creating an account on GitHub.
https://github.com/rnabioco/nihexporter
9 months ago
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Here for my first post. Our new approach to study tRNA aminoacylation by nanopore sequencing. Started as a napkin sketch ~1 year ago! This was a fun one, congrats to
@laurakwhite.bsky.social
and Aleks.
www.biorxiv.org/content/10.1...
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Nanopore sequencing of intact aminoacylated tRNAs
Transfer RNAs (tRNA) are decorated during biogenesis with a variety of modifications that modulate their stability, aminoacylation, and decoding potential during translation. The complex landscape of ...
https://www.biorxiv.org/content/10.1101/2024.11.18.623114v1
12 months ago
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