Marteinn Snæbjörnsson (@marteinnsn.bsky.social)

Happy to share our work on the mechanism of glycolysis in cancer now published in the journal Nature Metabolism. This was a large part of my postdoctoral work carried out in the lab of Prof. @almutschulze.bsky.social at the @dkfz.bsky.social and at Uni Wuerzburg. www.nature.com/articles/s42...

loading . . .

Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation - Nature Metabolism Snaebjornsson et al. explore a selective vulnerability in cancer elicited by targeting aldolase A, which causes energy imbalance and prevents further metabolic adaptations. https://www.nature.com/articles/s42255-024-01201-w