Matthew Tegtmeyer (@tegtmeyerlab.bsky.social)

@drannecarpenter.bsky.social @shantanuxsingh.bsky.social #preprint We developed NeuroPainting, an advanced morphological profiling tool adapted from Cell Painting, tailored for neural cells. This method captures over 4,000 cellular traits, setting a new standard for neuropsychiatric research. 🧠🔍

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Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion Neuropsychiatric conditions pose substantial challenges for therapeutic development due to their complex and poorly understood underlying mechanisms. High-throughput, unbiased phenotypic assays presen... https://www.biorxiv.org/content/10.1101/2024.11.16.623947v1