This trial to evaluate Bimzelx (bimekizumab) in Chinese patients with psoriasis, represents the largest clinical trial of bimekizumab conducted in an Asian population to date. #Psoriasis psoriasisclub.org/thread-8491....

Uncovering why inflammatory bowel disease patients face higher psoriasis risks and the role of epidermal growth factor receptor, body mass index and air quality. #Psoriasis psoriasisclub.org/thread-8490....

Icotyde (icotrokinra) demonstrated high rates of overall skin, scalp, genital and hand/foot psoriasis clearance, and improvements in nail psoriasis, through 1 year. #Psoriasis psoriasisclub.org/thread-8487....

Initial study reports distinct improvement from "Ozone Sauna & Ozonated Olive Oil" in the treatment of psoriasis with minimal risk. #Psoriasis psoriasisclub.org/thread-8486....

This review suggests macrophages might be the key to unlocking better psoriasis treatments. #Psoriasis psoriasisclub.org/thread-8484....

Psoriasis Club member Waine asks for footwear recommendations for psoriatic arthritis and plantar fasciitis. #Psoriaticarthritis See here: psoriasisclub.org/thread-8483....

What is Psoriasis Club? Find out here: psoriasisclub.com/about.html #Psoriasis

Does your lifestyle affect your psoriatic arthritis (PsA) ? this study looked at the latest research. #Psoriaticarthritis psoriasisclub.org/thread-8477....

Psoriasis Club is Sweet Sixteen. #Psoriasis #Psoriaticarthritis Read more ............................................ psoriasisclub.org/thread-8475....

A Korean nationwide cohort study looking at particulate matter (PM) and onset and exacerbation of psoriasis. #Psoriasis psoriasisclub.org/thread-8474....

Vanda Pharmaceuticals publish efficacy and safety results of Imsidolimab for generalised pustular psoriasis (GPP) #Psoriasis psoriasisclub.org/thread-8473....

Could psoriasis flares be linked to cellular energy and mitochondria? #Psoriasis psoriasisclub.org/thread-8472....

Kyntheum / Siliq (brodalumab) in patients with palmoplantar pustulosis psoriasis (PPP) demonstrated a long-term benefit not only to skin but also improved dermatology life quality index (DLQI) #Psoriasis psoriasisclub.org/thread-8471....

Is it time to rethink using bio treatments earlier for psoriatic arthritis (PsA)? #Psoriasis #Psoriaticarthritis psoriasisclub.org/thread-8470....

This Japanese study evaluated the treatment outcomes of stubborn (refractory) regions of psoriasis and psoriatic arthritis treated with biologics. #Psoriasis #Psoriaticarthritis psoriasisclub.org/thread-8469....

Unravelling the psoriasis and cardiovascular–kidney–metabolic (CKM) health link and its impact on life expectancy. #Psoriasis psoriasisclub.org/thread-8468....

This study investigated the role of proliferation-associated protein 2G4 (PA2G4) as a possible target for treating psoriasis. #Psoriasis psoriasisclub.org/thread-8467....

This multicentre retrospective study in Germany looked at patients with erythrodermic psoriasis using a wide variety of treatments. #Psoriasis psoriasisclub.org/thread-8463....

How demographics and family history redefine clearance predictions in psoriasis patients treated with biologics. #Psoriasis psoriasisclub.org/thread-8462....

This study looked at the effectiveness of interleukin-17 inhibitors (IL-17i) in treating anti-TNF-induced Paradoxical psoriasis (PP) in patients with Hidradenitis Suppurativa (HS) #Psoriasis psoriasisclub.org/thread-8461....

This study constructed a gene carrier with transdermal transfection capabilities, providing a new approach for gene delivery. This system achieves significant therapeutic effects in immune diseases like psoriasis. #Psoriasis psoriasisclub.org/thread-8460....

We seem to be stabilising and the forum is back online.

We are aware of some intermittent downtime on our forum and working to fix it. psoriasisclub.org

Glucagon-like peptide-1 receptor (GLP-1RA) agonist therapy is associated with improvement in psoriatic arthritis (PsA) related and metabolic outcomes. #Psoriasis #Psoriaticarthritis psoriasisclub.org/thread-8458....

Around one third of psoriasis patients experience skin pain, this study investigated what is going on. #Psoriasis psoriasisclub.org/thread-8457....

This study aimed to investigate treatment resistance mechanisms in palmoplantar psoriasis and assess the contribution of IL-17, IL-23, and IL-36α to the differential diagnosis. #Psoriasis psoriasisclub.org/thread-8454....

This study focused on the level of B-cell types in the whole blood of psoriasis patients and investigated the variability between Bregs and memory B cells and other classified B cells in the blood of psoriasis patients and healthy controls. #Psoriasis psoriasisclub.org/thread-8453....

Envudeucitinib is a next-generation oral allosteric inhibitor of tyrosine kinase 2 (TYK2) precision‑engineered for maximal 24‑hour TYK2 inhibition to correct immune dysregulation driven by proinflammatory mediators including IL-23 & IL-17 #Psoriasis psoriasisclub.org/thread-8452....

This study aimed to characterise changes in the diversity and composition of oral fungal and bacterial communities in psoriasis patients before and after treatment with IL-17 inhibitors. #Psoriasis psoriasisclub.org/thread-8449....

Adiponectin (APN) holds potential as an anti-psoriatic agent targeting Aurora kinase A (AURKA) and Forkhead transcription factor 1 (FOXM1) for the gene-targeted therapies in psoriasis treatment. #Psoriasis psoriasisclub.org/thread-8448....

This study analysed psoriasis-related mRNA microarray datasets, comprising 605 psoriatic plaque samples and 611 normal samples. These datasets were integrated into a cohort to systematically identify immune-related genes associated with psoriasis. #Psoriasis psoriasisclub.org/thread-8445....

This study examined the association between radiographic structural damage and physical function (PF) in psoriatic arthritis (PsA) #Psoriaticarthritis psoriasisclub.org/thread-8444....

This study provides valuable insights into the role of glucocorticoid receptor (GR) expression in psoriasis and its subtypes. #Psoriasis #Psoriaticarthritis psoriasisclub.org/thread-8443....

Blood based systemic inflammatory biomarkers are an easily accessible and cost effective tool for identifying psoriasis and partially mediating the association between psoriasis and depression. #Psoriasis #Depression psoriasisclub.org/thread-8440....

Update: "Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved Icotyde (icotrokinra), an interleukin-23 (IL-23) receptor antagonist for the treatment of moderate-to-severe plaque psoriasis. #Psoriasis psoriasisclub.org/thread-8322-...

This study assessed longitudinal changes in serologic and virologic hepatitis B virus (HBV) markers and evaluated the incidence of HBV reactivation in patients with moderate-to-severe plaque psoriasis undergoing long-term biologic therapy. #Psoriasis psoriasisclub.org/thread-8436....

This study demonstrated that at the time of generalized pustular psoriasis (GPP) diagnosis, patients with GPP have a high burden of both psoriasis-related complications and non–psoriasis-related comorbidities. #Psoriasis psoriasisclub.org/thread-8435....

Being independent with no advertising it's not easy to get our forum at "Psoriasis Club" noticed but recently we had a new member from Bluesky, so thank you to everyone that has given us a mention or repost. We appreciate it. 🙏 #Psoriasis psoriasisclub.org

Bimzelx better than Skyrizi in psoriatic arthritis first head to head study. #Psoriasis psoriasisclub.org/thread-8434....

This study provides a mechanistic foundation for luteolin-based interventions in psoriasis. #Psoriasis psoriasisclub.org/thread-8433....

This study demonstrated that strenuous exercise is associated with enhanced cutaneous, systemic, and enthesis-related inflammatory changes in an imiquimod (IMQ) induced psoriasis mouse model. #Psoriasis psoriasisclub.org/thread-8432....

This study found a non-linear positive relation between body roundness index (BRI) and Psoriasis (Pso) #Psoriasis psoriasisclub.org/thread-8429....

Ocadusertib is a selective allosteric inhibitor of receptor-interacting serine/threonine-protein kinase 1 (RIPK1) RIPK1 inhibitors have shown potential for the treatment of psoriasis but thus far, none have been approve. #Psoriasis psoriasisclub.org/thread-8428....

Balinatunfib is being developed as a potential new treatment for patients with psoriasis that selectively inhibits TNFR1 signalling to potentially stop or slow the disease-causing processes, while preserving signals initiated through TNFR2. #Psoriasis psoriasisclub.org/thread-8424....

These results suggest that the LIGHT/TNFSF14 axis may play a key role in regulating cytokine production by autoimmune cells and related pathways in psoriasis. #Psoriasis psoriasisclub.org/thread-8423....

This study identifies a novel role for G protein-coupled receptor 108 (GPR108) as a negative regulator of TLR7 signalling in psoriasis and may yield new therapeutic principles for managing psoriatic diseases. #Psoriasis psoriasisclub.org/thread-8422....

Alterations in neural innervation within psoriatic skin & delineate the functional contributions of sensory neuron-derived mediators, including ion channels, receptors, & neuropeptides in modulating psoriasis-associated immune dysregulation. #Psoriasis psoriasisclub.org/thread-8421....

In this cross-sectional analysis of a large, real-world Canadian cohort, G2-PASE demonstrated very strong correlation and excellent reliability compared with PASI. #Psoriasis psoriasisclub.org/thread-8420....

A team of researchers from the Department of Rheumatology and Immunology at Uniklinikum Erlangen have discovered which cells migrate from the skin of psoriasis patients to the joints and how they trigger inflammation there. #Psoriasis #Psoriaticarthritis psoriasisclub.org/thread-8419....

This study explored the global prevalence of obesity, abdominal obesity, and being overweight in patients with psoriatic arthritis (PsA). #Psoriaticarthritis psoriasisclub.org/thread-8417....