Nechama Wieder
@nechamawieder.bsky.social
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PhD candidate @ University of Oxford ~ UTRs ~
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Nechama Wieder
Sasha Gusev
3 months ago
I wrote about how genetic risk works in the context of embryo selection and how people often think about it all wrong. A short 🧵:
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What we talk about when we talk about risk
How embryo selection exploits our flawed intuitions about risk
https://open.substack.com/pub/theinfinitesimal/p/what-we-talk-about-when-we-talk-about?r=43f9ax&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
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Nechama Wieder
Nicky Whiffin
3 months ago
📣 We are recruiting! Please share!! Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺 We have two roles available 👇 🧵 1/4
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Iain Cheeseman
4 months ago
New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?
www.biorxiv.org/content/10.1...
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Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells
In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique...
https://www.biorxiv.org/content/10.1101/2025.07.22.666109v1
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Duncan Palmer
4 months ago
Deadline extended to August 1st! Fully funded DPhil (PhD) in Statistical Genetics at Oxford, available to international candidates!
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Super excited to share our new review paper - The role of untranslated region variants in Mendelian disease!
www.nature.com/articles/s41...
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The role of untranslated region variants in Mendelian disease: a review - European Journal of Human Genetics
European Journal of Human Genetics - The role of untranslated region variants in Mendelian disease: a review
https://www.nature.com/articles/s41431-025-01905-x
4 months ago
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Duncan Palmer
5 months ago
Come join us! We have an exciting PhD opportunity in statistical genetics at the University of Oxford. More info here:
bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025. Please share!
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Research Studentships | statistics
http://bit.ly/biomedDPhil
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Delighted to see my phenomenal phd supervisor get recognition for the all round fab scientist and super powerhouse she is! Go Nicky 🤩🥰
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12 months ago
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As a recent graduate of a DPhil in Oxford could not recommend it more highly! Check these out and apply 😊
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12 months ago
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