The non-monarchies that put their sitting leaders on money: Iraq Syria Turkmenistan Ghana Uganda Libya Turkey Kenya Tanzania Malawi Zambia Guinea Dominican Republic Bangladesh Vietnam Indonesia Botswana Tunisia North Vietnam

The best and the brightest from around the world studying at American universities is great for America. Our universities are magnets for the world's top talent. They draw them into America, where they often stay, build incredible companies, open great labs, become Americans!

When you create a maximally truth seeking AI and it conflicts with your worldview, you can do one of two things...

Ambition without mission is a sprint to nowhere.

IT'S TIME TO BUILD Big things. Bold things. Like replacing your local car dealership’s receptionist with ChatGPT apparently.

No program or course has given me more transformative insights into #company building and personal development than the 5050 UK program (www.fiftyyears.com). Each week, the @FiftyYears team mentors us on how to develop the traits of great founders… Thread. www.linkedin.com/posts/bjorno...

The best possible future is one in which the US and China build the future together as allies.

Convening a dozen federal agencies. To tackle healthcare? AI policy? Economic growth? No. To go after Harvard.

80% of Chinese STEM grads stay in the US. They build American companies, advance American science, power the American economy. The ones that go back home PAID to be influenced by America. They often return with a love of the USA and a deep connection to America.

Harvard’s refusal to bow to authoritarian pressure is goddamn impressive.

A great strength of America is that the best and brightest from around the world clamor to come here. To innovate and build on our shores. Why are we fighting to change that?

Israel and the United States causing and allowing the mass starvation of women and children will only radicalize another generation. It's the surest way to prolong the cycle of violence. It makes Israel less safe and is unfathomably cruel to the people of Gaza.

It’s fair to ask why everyone in the US gets due process before deportation, including those here illegally. The answer is simple: without due process for everyone, the government could deport citizens, because due process is how citizens prove they are citizens.

Metformin might be the most studied longevity drug that’s already FDA approved. Improves insulin sensitivity, fitness, and immune function in healthy adults. elicit.com/review/22d92...

The great strength of America is that it attracts the best and the brightest from around the world. For the first time in modern history, America is facing a brain drain. This is how you give up the future. www.nature.com/articles/d41...

If you wanted to absolutely gut American manufacturing capabilities, you would tax manufacturing inputs to drive up the cost of manufacturing things in the US, while taxing imported finished products at a lower rate, to advantage companies that manufacture overseas.

1/ GOODBYE ANIMAL TESTING Big news from the FDA: They're starting to phase out animal testing requirements for monoclonal antibodies and other biologics. HUGE DEAL for science, ethics, and innovation.

So much potential is lost to shallow but lucrative pursuits.

A trade deficit doesn't mean your country is being screwed. It means your country is rich.

"Walt, that's crazy." Everyone was against building Disneyland -- Walt’s finance team, his cofounder brother, his employees, even his wife! But Walt had the vision and moral authority of a founder and pushed it through. Last year, Disney Parks brought in $34B. $9B in profit.

Deep tech is the closest thing we have to magic.

Sure the markets are way down but at least there's a measles outbreak.

We sent this email to all Fifty Years portfolio founders 2 weeks ago. Subject "Farewell, stability".

21 biotech startups. Nobel Prize. AI for protein design breakthroughs. The US was building the future. Then it defunded the science behind it. World-class self-own. www.geekwire.com/2025/from-no...

New head of the FDA 🤦 en.wikipedia.org/wiki/Marty_M...

Getting a lot of questions about our billboard outside SpaceX. Great engineers want to build. They don't want drama and social media impacting their work. In 10 years in venture, we've never seen more SpaceX and Tesla engineers leaving to start companies.

New billboard dropped in Hawthorne.

who did this 👀

👀

VC should fund things that give humanity new powers, not just incremental efficiency gains.

Modern day venture is sick. It is unwell. Most VCs think the job is to chase markups. Invest, then sell the company to the next round VCs at a higher price. That ain't it. Venture done right is helping founders build indispensable companies for the long haul.

We need a better plant bioengineering toolkit.

About 5 years after launch, BillionToOne just reached their 1 millionth UNITY prenatal test. They're now at a run rate of 500K tests / year. Deep tech PhD founders Diagnostics startup All things most VCs say = slow growth. The reality? $0 to $200M ARR in ~5 years.

After cutting off all humanitarian aid, Israel has now cut off all electricity into Gaza. This shuts down desalination plants, meaning no clean drinking water. Depriving civilians - half of them children - of drinking water is not self-defence. It's a war crime.

Trump announcing a strategic crypto reserve and a day later all cryptos being seriously in the red tells you everything you need to know about what people think of this administration.

Incredible. Slava Ukraini.

CRISPR, GPS, MRIs, computers, the Internet, Google, flu vaccines, ultrasound, recombinant DNA, neural networks, deep learning, network routers, browsers, CMOS, RSA, mRNA, immunotherapies, and hundreds of other civilizationally important technologies came out of 🇺🇸 academic labs.

A startup is manufacturing things in space and returning them to earth and you're excited about AI marketing automation?

1/ Is DOGE the most incompetent agency in American history? DOGE, created by Trump and led by Elon Musk, aimed to slash “waste, fraud, & abuse.” Instead, it slashed public health programs, nuked safety oversight, and botched basic math. The receipts...

The next time you see Elon tweet something as fact, remember that he couldn't tell the difference between reality and a scene from a Batman movie.

Stop dunking on Trump supporters who criticize his bullshit by digging up their old endorsement of him. Only broad-based opposition will stop our country from being torn up and if you keep dunking on them, they'll stop criticizing him. It's good to change your mind.

Long covid is not "vaccine injury". There's simply no evidence to suggest that long covid is caused by vaccines. In fact, the incidence of long covid is far lower in people who are vaccinated. See for yourself: elicit.com/review/51237...

1/ Ukraine didn't start the war. Russia invaded Ukraine. 2/ Half the money has not gone missing 3/ Zelenskyy is very popular in Ukraine 4/ Zelenskyy was popularly elected, not a dictator 5/ Ukraine isn't holding elections because they're fighting off an invading Russian army

"You do understand you have no idea what you're talking about, right?"

1/ Ever wonder how a clearly brilliant person – someone great a math and engineering and company building – can display shockingly unintelligent thinking when it comes to politics? Neuroscience has the answer!

You have the potential to shape civilization like never before and you're working on AI sales agents?

When I was 12 my house exploded because of a propane gas leak. My single mom suffered a brain injury and became disabled. She couldn't hold a job. I caddied to help support the family. Food stamps helped us keep the fridge from being empty. So grateful for that support we had.

"Efficiency" means better output over costs. That's not the same as simply reducing costs. Say you have a system that's 100 output for 10 cost. Taking it to 110 output for 8 cost -- that's efficiency. Taking it to 20 output for 5 cost is INEFFICIENT cost cutting.