Bone health in patients with cancer: a multidisciplinary Spanish consensus; review of risk factors, assessment strategies, and management approaches. C Beato‑Zambrano et al. Clin Transl Oncol 2026 Feb 17 shorturl.at/bVuT5

In vivo mechanical assessment of cortical bone rigidity of non-dominant midshaft ulna enhances fracture discrimination beyond DXA in PMP women. BC Clark et al. JBMR 16 Feb 2026 shorturl.at/ZINg3 ...more accurately identified women with past fractures than DXA did

Balancing risks in febrile hip fracture patients: is surgical delay more dangerous than infection? S Balziano et al. Osteoporos Int 16 Feb 2026 shorturl.at/B93Hl ... early surgery in febrile hip fracture patients may be safe when guided by individualized assessment

Psychotropic medication use and bone fracture risk among patients with multiple sclerosis: a real-world study. Po‑Chun Wang et al. Osteoporos Int 16 Feb 2026 shorturl.at/dwXuW ... increased fracture and relapse risk driven primarily by opioid analgesics, without an effect on mortality

Multidisciplinary management of acute osteoporotic vertebral fracture: results of a national Delphi consensus. L Alvarez‑Galovich et al. Arch Osteoporos. 16 Feb 2026 shorturl.at/k6jaE ... establishes a standardized and multidisciplinary clinical framework for managing acute OVFs in Spain

Surgical treatment of a Type IIIA open tibia fracture in a patient with Fibrodysplasia Ossificans Progressiva. ER Nakken et al. JBJS Case Connect 2026 Jan 15 shorturl.at/ALz8J 64year old patient regained 90% of baseline function at 1 year, without significant heterotopic bone formation

"We can have democracy in this country, or we can have great wealth concentrated in the hands of a few, but we can't have both." –Justice Louis Brandeis Words spoken many years ago that are just as relevant today. We must continue the fight to get big money out of politics.

Lactate targeting: Regulatory networks and therapeutic potential in bone diseases. Xiyue Zhang et al. .Int Immunopharmacol 2026 Feb 14 shorturl.at/Lt93x ... either a beneficial or detrimental role by exerting distinct effects on various cell types in different contexts of bone diseases

Attenuation of Transforming Growth Factor-β Signaling Promotes Complete Recovery of Trabecular Bone Structure Following Immobilization With Traumatic Spinal Cord Injury in mouse model. K Sahbani et al. FASEB J 2026 Feb 28 shorturl.at/ZSbCX …promising

Management of Fractures of the Thoracolumbar Spine-A Narrative Review. SY Vetter et al. J Clin Med 2026 Jan 27 shorturl.at/oBMcO study combined clinical expertise and opinions with the current best scientific evidence from a selective literature search

Association between serum uric acid levels and osteoporosis risk: evidence from a cross-sectional study and Mendelian randomization analysis. Qi‑Pei Liu et al. Clin Rheumatol 2026 Feb 14. shorturl.at/eFocv

Under-prescribed and underutilized: US trends in osteoporosis medication use after fragility fracture. H Wadhwa et al. Bone 12 Feb 2026 shorturl.at/rfl73 … only 8% of patients with fragility fractures receive osteoporosis medication ...not MAGA?

Autoimmune osteomalacia: a novel FGF23‑related hypophosphatemic osteomalacia with autoantibodies against PHEX. Y Hoshino & N Ito. J Bone Miner Metab 14 Feb 2024 shorturl.at/3BQQn ... review ...revisit the clinical features of the five previously reported patients with AIO

Bone health in Parkinson’s disease: a comprehensive review of bone involvement and its pathophysiological mechanisms. E Toussirot et al. Front Med (Lausanne). 2026 Jan 13 shorturl.at/3C4qY

Delayed Neurological Deficits caused by epidural leakage of intravertebral contents in a patient with Osteoporotic Vertebral Fracture. F Mamoru et al. Cureus. 2025 Dec 30 shorturl.at/XA4Y6 ... rare case in a patient with both OVF and Parkinson’s Disease ...possible role dyskinesia

Drug-Induced Osteoporosis; review. RW Gasser et al. J Clin Med 2026 Jan 26 shorturl.at/Z3aCU ... when prescribing potentially bone-damaging medications over extended periods, particularly in older individuals, bone health should be proactively considered

Trump does not care

Parathyroid Hormone in the Management of Pelvic Fragility Fractures: A Systematic Review and Meta-Analysis. SA Crooks et al. J Clin Med 2026 Feb 3 shorturl.at/iU7O9 ... may improve bone healing and visual analogue pain scores, although the evidence is limited

Skeletal Involvement in Systemic Mastocytosis: Pathophysiology, Clinical Management, Standards of Care, and Novel Therapeutic Strategies. M Fazio et al. Cells 2026 Feb 6 shorturl.at/UUqeQ ... narrative review and update ...comprehensive literature search

Health and adverse events associated with extended oral bisphosphonates; syst .rev. P Oka et al. JCEM 2026 Feb 10 shorturl.at/NMDqN ...substantial heterogeneity and limited high-quality evidence precludes definitive conclusions

The Scientific Case for Animal Models: A Perspective From Musculoskeletal Researchers. M Hadjiargyrou et al. FASEB Bioadv 2026 Feb 9 shorturl.at/sIdyu … review highlights the necessity of animal models and the complementary role of New Approach Methodologies

Bisphosphonate-Associated Orbital Inflammation; case report. Danielle N Kundert et al. JAMA Ophthalmol 2026 Feb 12 shorturl.at/z3RG3 …rare adverse effect after iv 5 mg zoledronate and successful systemic treatment with corticosteroids

Comparative analysis of BMP signaling in human endothelial colony-forming cells human (ECFCs) reveals vascular bed-dependent ALK2 expression. Nadine Z Großmann et al. Vasc Biol 2026 Feb 11 shorturl.at/Gb4vc ...options for strategic use of in regenerative medicine and disease modelling?

Will Selective Androgen Receptor Modulators Ever Reach The Clinic? J Pena Dias et al. JCEM 11 Feb 2026 shorturl.at/HY3dl likely to enter clinical practice in select niches, especially among the frail, the elderly, or individuals with excessive loss of lean body mass ...no strong RCTs available yet

The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva. LR Hanson et al. Bone 9 Feb 2026. shorturl.at/cvJbD ... new model of injury-induced HO for understanding early events in FOP

Impact of Current and Previous Smoking on Fracture Risk in Older Women: The Role of Physical Function, Bone Density and Bone Microarchitecture. M Zoulakis et al. JBMR 10 Feb 2026 shorturl.at/yzFRW …smokers have increased risk of fractures, especially hip fractures

Nutrients and Metabolites as Signalling Molecules in Osteoclasts. K Chandrasekaran et al. Curr Osteoporos Rep 9 Feb 2026 shorturl.at/mGS6o ...new interesting insights

Lithium and the Brain-Bone Axis: A Bridge between Osteoporosis and Alzheimer's Disease. Ji-Won Lee et al. Curr Osteoporos Rep 2026 Feb 10 shorturl.at/eVKEX ... may simultaneously protect against osteoporosis and neurodegeneration ...excellent update

Low-dose lithium supplementation promotes musculoskeletal and metabolic health in ovariectomized female mice. BM Marcella et al. J Physiol 2026 Jan 8. shorturl.at/5LGyX ... may reveal a viable therapeutic option for postmenopausal females

Scoliosis in Fibrodysplasia Ossificans Progressiva; A Report of 4 Cases. Z Elsabbagh et al. JBJS Case Connect 5Feb 2026 shorturl.at/uAOVp ... surgical correction can relief symptoms and improve QoL, but can also carry substantial risks, including perioperative com plications and new HO

Olympics Update: Trump Wins Gold in Downhill Presidency open.substack.com/pub/borowitz...

As anticipated, now it's happening www.nature.com/articles/d41...

Semaglutide and Tirzepatide use was associated with greater annualized total hip bone loss in patients without DM, whereas loss was comparable between GLP-1 RA and controls in patients with DM. Yi Liu et al/ JCEM 2026 Feb 7 shorturl.at/CUO5Z …retrospective one center study in NY

Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes. ML Doolittle et al. J Clin Invest 2026 Jan 27 shorturl.at/W9EGq …aged bone marrow myeloid cells do not achieve the fully developed senescent phenotype originally described in mesenchymal cells

MicroRNA Networks Driving Skeletal Aging and WNT Pathway Modulation. D Achudhan et al. bioRxiv 2026 Jan 25 shorturl.at/SK4Zi …relationship is further explained using Scl-Ab secreted mainly by the osteocytes …hallmark paper of skeletal senescence research

Treatment of pediatric chronic nonbacterial osteomyelitis (CNO). S Turner et al. Autoimmun Rev 2026 Feb 5 shorturl.at/A9aAV … a clear systematic review … randomised prospective trials urgently needed

Bone Organ- on- a- Chip uncovers that TPD52L1 enhances osteogenic differentiation of MSCs and contributes to osteoporosis repair. Z Liu et al. FASEB J. 2026 Feb 28 shorturl.at/MNeNZc … fine experiments

Romosozumab can be an effective and safe anabolic option for patients with thalassemia and severe osteoporosis. MP Yavropoulou et al. JBMR Plus 5 Feb 2026 shorturl.at/YX9J6 … case reports of two female patients

PTH induced osteoblast Slit3 to decrease aberrant sensory innervation in degenerated vertebral endplates to relieve low back pain in mice. W Zhang et al. Bone Research 22 Jan 2026 shorturl.at/Jydzg …could explain the sometimes found clinical observations of pain decrease with PTH

Liver-derived, plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men. M Mahmoodi et al. Matrix Biol 2025 Dec 7. shorturl.at/FnZDg … suggesting association with fracture risk in men

Circadian regulator PER1 inhibits osteoclastogenesis by activating inflammatory genes N Katoku-Kikyo et al. JBMR 5 Feb 2026. shorturl.at/Oo53U …novel insight bone loss by circadian disruption and inflammation

The Osteoporotic Fractures in Men Study (MrOS): a 25-year landmark study of skeletal health in older men. JA Cauley et al. JBMR 5 Feb 2026 shorturl.at/IYaGL …fine overview and summary of results

Bone complications in Cushing`s syndrome in European registry study of 1682 patients of which 766(45%) had DXA examination at baseline, of whom 157 OP at spine and 103 at hip. A Z-Wełna et al. Ann Endocrinol 2026 Feb 3. shorturl.at/7ZGxJ …disappointing neglect of care for bone health?

Clear mismatch between high fracture burden and low clinical engagement in bone health assessment in 79 patients with endogenous Cushing's Syndr. treaed in Imperial College NHS Trust, London. P Behary et al. Clin Endocrinol 2025 Dec 21 shorturl.at/rLzmj …no clinical guidelines present!

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office | Science | AAAS www.science.org/content/arti...

The role of newly identified circular RNAs in mediating the protective effects of exercise against muscle degeneration and aging. Bo Li et al. Biogerontology 30 Jan 2026 shorturl.at/JYsNy ...very interesting but many knowledge gaps

Diverse exercise modalities in alleviating osteoporosis: a narrative review. W Zou & R Liu Endocrine 3 Feb 2026 shorturl.at/f9oBf …illustrative fine educational review

Prediabetes Associates With Musculoskeletal Alterations Independent of Total Body Adiposity. Alan Fappi et al. J Cachexia Sarcopenia Muscle 2026 Feb shorturl.at/Iedm5 … is associated with greater fatigability during repeated contractions with important clinical implications