A new #challenge in #digital #psychiatry: #AI chatbots and #psychosis 🤖 A case report describes how a personified #chatbot reinforced #delusional beliefs and undermined #antipsychotic adherence in a #patient with first-episode psychosis 🧠 https://ow.ly/fgGU50Ziwl3

How do we distinguish #drug #sideeffects from mood relapse in #bipolar #disorder? 🧠 A case report describes severe #restlessness, “buzzing” sensations, and manic-like symptoms following atomoxetine initiation in a patient with bipolar I disorder and #ADHD https://ow.ly/znCX50ZiwjC

Inhibition in #schizophrenia may be disrupted in “#time and #frequency.” New MEG evidence shows stage-specific low gamma alterations in the rIFG–preSMA circuit, revealing how fast-response control breaks down in early #psychosis https://ow.ly/jAUY50Ziwj7

How does #depression reshape #stress and #reward circuits in the #brain? New resting-state 7T fMRI data show reduced connectivity between the #BNST and ventral #striatum in individuals with MDD, suggesting altered communication in key affective circuits 🧠 https://ow.ly/KHzB50ZiwiG

How does #age of onset shape #brain function in #OCD? 🧠 Multimodal imaging data suggest shared thalamic alterations across OCD subtypes, while early-onset #cases show distinct changes in #occipital functional activity https://ow.ly/b0Sf50Ziwi5

What will define the next 50 years of #psychiatric #neuroscience? 🧠 Submit your research to our collection bridging mechanism and #clinic, from neural circuits to #biomarkers, computation, and treatment targets https://ow.ly/OufH50Ziwhi#psychiatric#neuroscience?#clinic#biomarkersdline: Jan 31, 2027

#Clinical studies deserve a #journal that reaches both #clinicians and #neuroscientists 🧠⚕️ JPN publishes work across psychiatry and brain science with strong #visibility and a rigorous, expert-led #review process https://ow.ly/kl7V50Z6pE5

Can depression be understood as a “speed disorder”? 🧠⏱️ New perspective proposes that #depression may involve a core disturbance in the #speed of brain and behavioural processing This “abnormal slowness” could cut across #emotional, #cognitive, #motor, and #sensory symptoms https://ow.ly/RSZM50Z6qtl

#Smoking isn’t just habit—it’s #brain network dynamics 🧠🚬 New #research shows disrupted causal connectivity within default mode network subsystems is associated with #automatic smoking behaviour in #tobacco use #disorder 🩺 https://ow.ly/fSOG50Z6pJL

What happens in the #brain during #emotion regulation in #depression? 🧠 A new Journal of #Psychiatry and #Neuroscience meta-analysis maps consistent patterns of hyperactivity in emotion-related regions and reduced activity in #cognitive #control circuits https://ow.ly/IfVt50Z6qmi

#Knowledge as an intervention? 🧠📚 This JPN #editorial argues that #neuroscience #education may help empower individuals living with #addiction by explaining how #brain systems change with s#ubstance use and #recovery ❤️‍🩹 https://ow.ly/5ZLP50Z6pNF

How does the #gut influence the #aging #brain in #depression? 🧠🦠 A new Journal of #Psychiatry and #Neuroscience study links gut microbiota composition with altered brain functional connectivity in late-life depression 🧬 https://ow.ly/zK8x50Z6pUS#gut

How do #psychedelics reshape the #brain — and experience? 🧠🌈 This JPN #review examines mechanisms from 5-HT2A receptor signaling to default mode #network modulation and #neuroplasticity 🧫 https://ow.ly/jMno50Z6q5t

The #immune system and #brain may be more connected than we think 🧠🛡️ New #research shows changes in peripheral T lymphocyte #aminoacid #metabolism in a #ketamine model of #schizophrenia - like behavior 🧬 https://ow.ly/58yk50Z6pAJ

How does the #brain distinguish self-generated actions from external events? 🧠👁️ A new study shows disrupted corollary discharge signalling during #eye movements in both #schizophrenia and #bipolar disorder with psychotic features 🔬 https://ow.ly/huTt50Z6pyA

Is #adult #neurogenesis in the #human hippocampus real—and how much is there? 🧠🔬 A spatial #transcriptomic analysis finds very low levels of hippocampal neurogenesis in humans, but suggests a potential “reserve” of #plasticity remains in the adult #brain https://ow.ly/jja750Z6qbJ

How do #psychiatric disorders shape #decision-making? 🧠🎲 A new Journal of #Psychiatry and #Neuroscience study compares model-based vs model-free learning across #depression, #OCD, and #schizophrenia — revealing both shared and disorder-specific patterns 🧐 https://ow.ly/7Shx50Z6pvj

Can #brain dynamics predict #treatment response in #panic disorder? 🧠⚡ A new Journal of #Psychiatry and #Neuroscience study finds that temporal variability in insula and lingual gyrus connectivity may help distinguish responders from non-responders early in treatment 💊 https://ow.ly/oOqm50Z6prB

New insights into the #neurochemistry of #psychosis progression 🧠⚡ ACC #glutamate levels differ across #genetic high-risk, clinical high-risk, and first-episode #schizophrenia — suggesting a non-linear trajectory across illness stages https://ow.ly/OwNh50Z6pnC

Some of the most memorable advances in #psychiatry start with a single #case 🧠🔬 We invite case study submissions that offer clear #clinical or #mechanistic insight into #brain and #behavior https://ow.ly/XkUw50Z6pb5

Toward early detection of #schizophrenia risk 🧠🔬 This study integrates MEG and #behavioral data to identify #neural signatures that may help stratify #clinical and familial risk 💊 https://ow.ly/O2S050Z6p5l

What happens in the brain’s stress–#reward circuitry in #depression? 🧠 New 7T #fMRI research shows reduced connectivity between the BNST and ventral striatum in individuals with major depressive disorder 🔬 https://ow.ly/9fml50Z6p3f

Does #age of onset matter in #OCD #biology? 🧠 New study finds distinct functional #brain differences between early- and late-onset OCD, including altered thalamic and occipital activity 💊 https://ow.ly/SUam50Z6p1e

🧠🏆 #Quan #Prize Winner Spotlight How does the #brain reorganize during #learning—and what happens when that flexibility breaks down in #schizophrenia? This award-winning study introduces a new way to measure dynamic brain network change #Neuroscience #MentalHealth https://ow.ly/FVpO50YRxgc#Quan

🫀🏆 #Quan #Prize Winner Spotlight Clozapine saves lives in treatment-resistant #schizophrenia—but in rare cases can trigger myocarditis, a potentially fatal #cardiac inflammation. This award-winning study explores why #Psychiatry #PrecisionMedicine https://ow.ly/fPbJ50YRxfS

This year’s #Quan #Prize recognizes two exceptional studies pushing #psychiatry forward: 1️⃣ Predicting clozapine-induced myocarditis, and 2️⃣ Brain network flexibility in schizophrenia during learning Bold #science with real clinical relevance 🧠🏆 #MentalHealth https://ow.ly/NXob50YRxfm

Getting involved in peer review offers more than just service to the field. It’s an opportunity to engage with new research, improve your own work, and contribute to the quality of published science. See what’s involved 👥▶️ https://ow.ly/43MJ50YNC35 #PeerReview #AcademicPublishing

#Climatechange is a #mentalhealth issue 🌎 Rising #temperatures, #wildfires, displacement, grief, #anxiety, #depression, and #trauma are increasingly linked to our warming world! Researchers must be part of the solution https://ow.ly/gfbg50YRxcs

Your #genes may shape how #depression-related #brain networks communicate—even before clinical depression appears 🧬 Research links polygenic risk for depression with altered connectivity of the subgenual anterior cingulate cortex in young adults #Neuroscience #Psychiatry https://ow.ly/JYEm50YRxeg

A 22-year-old woman with Prader–Willi #syndrome experienced marked improvement in compulsive #overeating and severe s#kin picking after treatment with topiramate 💊 A striking example of #personalized #medicine in rare disease #psychiatry https://ow.ly/Gy7T50YRxcM

Could a #blood test one day help characterize #depression severity? 🩸 Researchers found specific #DNA methylation signatures associated with symptom burden in major depressive disorder #MentalHealthResearch #Biomarkers https://ow.ly/iSVk50YRxb3

#Vitamin B12 is usually seen as a marker of #nutritional adequacy—but in #anorexia nervosa, the story may be more complex 🤔 Researchers found elevated #B12 levels in patients, suggesting #blood B12 may misrepresent nutritional status #EatingDisorders #MentalHealth https://ow.ly/s30O50YRx9O

#NowHiring: Institutional Account Manager with experience in sales. Apply now: 🇨🇦 Canada: https://ow.ly/JrTJ50YRgin 🇬🇧 UK: https://ow.ly/Zuyi50YRgbC 🇩🇪 Germany: https://ow.ly/MQn750YRgbE #NowHiring#AcademicPublishing

Patients come to #psychiatry to talk So why aren’t conversations treated like #clinical data? New perspective argues that #speech, #language, facial cues, and movement can be quantified with #AI to improve diagnosis and clinical decision-making #MentalHealth #Neuroscience https://ow.ly/EFZ450YRx7h

Can #brain activity help detect #suicide risk more objectively? 🧠 New research found #patients with a recent suicide attempt showed distinct resting-state EEG connectivity patterns compared with patients experiencing suicidal ideation alone #Neuroscience #MentalHealth https://ow.ly/1MmT50YRx6i

FACETS at 10 webinar recording now available. Hear perspectives on the future of interdisciplinary research from leading Canadian researchers. Watch the discussion ▶️ https://ow.ly/VZH250YTz8j #InterdisciplinaryResearch The Royal Society of Canada // La Société royale du Canada FACETS Journal

What happens when AI becomes a patient’s most trusted voice? #AI #chatbots can: 🗣️ Reinforce #delusions 💊 Undermine #treatment 🤝 Replace real-world #support 19-year-old with #psychosis followed “medical advice” from AI—which told him his #medication was #poison https://ow.ly/bKr550YJ19y#AI

Eph receptors are a family of tyrosine #kinases activated by ephrin ligands—best known for guiding #brain development: ✔️ #Neuronal growth ✔️ Axon guidance ✔️ #Cell survival But what happens after #development ends? https://ow.ly/XuY650YIYqp

Treating #ADHD in #bipolar disorder isn’t straightforward Stable patient developed intense “buzzing,” and #manic-like symptoms after starting atomoxetine—blurring the line between #sideeffect vs relapse 💊 Even “low-risk” #meds require close monitoring in complex patients https://ow.ly/xafH50YJ1g4

What if treating #OCD isn’t about what you target—but which #brain circuit? Meta-analysis shows #neuromodulation—targeting the fronto-limbic circuit—offers the strongest, most consistent improvements in #treatment-resistant OCD. A shift toward circuit-based #psychiatry 🧠 https://ow.ly/7JiN50YJ1mu

Does #cannabis affect #men and #women differently? The science isn’t clear 🌿 Review finds only 6/29 studies show any #sex differences in #cognitive effects 🧠 but they're underpowered, poorly defined, and excludes gender-diverse individuals We need more #inclusive science! https://ow.ly/PyPG50YJ1C0

It’s #EarthDay 🌎 Eat smarter for your health & the planet. Improving school & community food environments is a step forward Blais et al. evaluate the nutritional quality of Canadian #SchoolFoodPrograms & find room for improvement Read it here 🔗 https://ow.ly/ImkL50YNcxb#EarthDay📸 Jonathan Borba on Unsplash

Why do some people develop hazardous #drinking patterns while others don’t? 🥃 #MachineLearning study validates a neuroclinical framework of #addiction and finds that reward “pull” & drinking to cope are the strongest drivers of #alcohol risk, outperforming impulsivity alone https://ow.ly/hH8150YJ1sM

A 19-year-old with first-episode #psychosis wasn’t responding to treatment 💊 The reason? An #AI chatbot he trusted—“the only one who understands me”—was telling him his medication was poison! A striking case of how AI can unintentionally reinforce #delusions https://ow.ly/BTcO50YJ11U#psychosis

Can brain waves help detect #suicidal ideation in late-life #depression? New research shows altered gamma-band #brain networks—especially in the orbitofrontal cortex—may act as potential biomarkers for suicide risk 🧠 ⚡ https://ow.ly/r0yc50YJ0H8

What if a key system that shapes the #brain during development is still quietly influencing #mentalhealth in adulthood? New research dives into the Eph–ephrin signaling system—and its emerging role in disorders like #depression, #autism, and #schizophrenia 🧠 https://ow.ly/MIUy50YIYli

What if we stopped treating #brain connectivity as #static? This #award-winning paper tracks how network importance shifts moment-to-moment during learning — revealing entropy & inflexibility in #schizophrenia. A powerful new lens on #psychiatric illness. 🔍🧠 https://ow.ly/7kH650YpcyC

From #stem #cells to precision #psychiatry #Award-winning study models clozapine exposure in patient-specific heart cells, revealing #immune & #stress-response pathways that may drive myocarditis risk 💊 Personalized risk prediction may be closer than we think 💭 https://ow.ly/UbOk50Ypcuq

Honouring a legacy of #excellence in #psychiatric research Dr. Francis Wayne Quan Memorial Prize commemorates Francis Wayne Quan — #psychiatrist, founding #editor, and champion of #Canadian #mentalhealth #scholarship Congratulations to our 2025 winners! 🇨🇦✨ https://ow.ly/2pCz50YpcFk

Cerebral small vessel #disease (CSVD) is a leading cause of white matter damage 🧠Understanding early #markers could help detect risk before symptoms appear. Could #blood #inflammation signals be the early warning? 🔬 #CognitiveHealth https://ow.ly/xAKX50Yh9f0