Why do past traumas increase risky cannabis use? 🤔 Altered striatal–cortical circuits may potentiate craving after trauma, while cannabis cues activate corticolimbic pathways. 👉 doi.org/10.1503/jpn.... #Neuroimaging #CannabisUse #MentalHealthResearch

🧠 How are elevated BDNF levels linked to #autism? New #research shows that in children with ASD, increased peripheral BDNF is associated with oxidative stress—and reversing it in mice rescues autism-like behaviors. 👉 doi.org/10.1503/jpn.... #AutismResearch #Neurodevelopment #BDNF

This study moves beyond brain regions to explore how obsessive–compulsive disorder may be rooted in broader brain network disruptions. Learn more ➡️https://buff.ly/be859Sw #PsychiatryResearch #Neuroscience #OCDResearch 📸jpn.240145-fig1

🧠 How do brain blood flow and white matter structure interact in youth with bipolar disorder? New research finds ACC blood flow is linked to cingulum white matter integrity—especially in asymptomatic females. 👉 doi.org/10.1503/jpn.... #Neuroimaging #BipolarDisorder #YouthMentalHealth

Celebrate #PeerReviewWeek with us! This week highlights the essential role of reviewers in scholarly publishing. Learn how you can contribute through peer review 📖▶️ buff.ly/aG0O0C2 #PRW2025

We’re in Montréal at the CCNP 47th Annual Meeting. Stop by and connect with Journal of Psychiatry & Neuroscience! #MentalHealthResearch #Neuropsychopharmacology #CCNP2025

Could psychedelics offer relief from depressive and negative symptoms in schizoaffective disorders? New to @cdnsciencepub.com's portfolio, JPN brings new insight into this connection through original research, reviews, and more ➡️ buff.ly/V23qEJS 📸 jpn.250005-fig1

Heading to Montréal for the CCNP 47th Annual Meeting? Come visit us! We’re excited to connect with researchers and colleagues. #MentalHealthResearch #Neuropsychopharmacology #CCNP2025

📊 How real is the youth mental health crisis? A new editorial examines national & provincial trends in symptoms, suicidality, and healthcare use — and explores why interpreting these numbers is more complex than it seems. 👉 doi.org/10.1503/jpn.... #YouthMentalHealth #PublicHealth #SuicidePrevention

We are thrilled to be attending the Canadian College of Neuropsychopharmacology 47th Annual Meeting in Montréal from September 17–19! We can't wait to connect with the amazing community. Come say hi! #MentalHealthResearch #Neuropsychopharmacology #CCNP2025

@jpnjournal.bsky.social publishes work that helps us understand the brain processes behind psychiatric disorders. Sign-up to our newsletter by selecting the Journal of Psychiatry and Neuroscience as your journal preference! ➡️ buff.ly/jOJA1zh #PsychSciSky #Neuroscience #Neuroskyence

Explore Canada’s youth mental health crisis: rising distress, social media impact, and barriers to care. Read more in @jpnjournal.bsky.social ▶️ cdnsciencepub.com/doi/full/10.... #YouthMentalHealth #MentalHealthCanada #MentalHealthAwareness

We’ve joined a new publisher! Excited to partner with @cdnsciencepub.com as we continue publishing leading research in brain and mental health science. Learn more ➡️ buff.ly/RnlFsYt #AcademicSky #SciComm 🧪 #PHDSky #PsychSciSky #Neuroscience #Neuroskyence

Prematurity and low birth weight with prenatal benzodiazepine exposure: Benzodiazepine exposure in the third trimester is linked to increased risk of preterm and small-for-gestational-age births. ➡️https://doi.org/10.1503/jpn.240063

Cognitive training and tDCS for borderline personality disorder: A combined approach was well tolerated and showed improvements in cognitive performance, symptoms, and functioning. ➡️https://doi.org/10.1503/jpn.250041

Risks of prematurity and low birth weight associated with trimester-specific prenatal benzodiazepine exposure. New articles on prenatal benzodiazepine exposure and borderline personality disorder. ➡️https://www.jpn.ca/content/50/4

Childhood trauma and HDM in psychosis: Do alterations in hippocampal-dependent memory underlie the relationship between developmental trauma and psychosis? ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.240150

Weight loss and clozapine levels: Given the recent surge in use of GLP-1 agonists, it is likely that more patients taking clozapine may experience weight loss and worsening of schizophrenia symptoms. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250076

Youth mental health in Canada: Mental health professionals have the obligation to listen to youth and to develop clinical, evidence-based programs and research initiatives to support their needs. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250115

Are the kids alright? Making sense of the current youth mental health crisis in Canada through heuristics and data. New articles on youth mental health, weight loss and clozapine, and childhood trauma. ➡️https://www.jpn.ca/content/50/4

Transcranial direct current stimulation for ADHD: Stimulation may improve the attention and inhibitory abilities in ADHD, particularly with optimal stimulation parameters. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250032

Trauma and cannabis cue–induced functional connectivity: Trauma- and cannabis-related cues may potentiate cannabis craving through altered reward circuit functional connectivity. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250064

Trauma and cannabis cue–induced reward circuit functional connectivity in cannabis users with trauma histories. New articles on cannabis use with trauma history and ADHD. ➡️https://www.jpn.ca/content/50/4

Serotoninergic psychedelics for schizoaffective disorders: Psilocybin-assisted therapy reduced depressive and negative symptoms without worsening psychosis in a patient with schizoaffective disorder. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250005

BDNF and oxidative stress in autism: Elevated BDNF in autism is linked to oxidative stress; reversing the redox imbalance in mice normalizes BDNF and improves autism-like behaviours. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250087

Cerebral blood flow and white matter integrity in youth bipolar disorder: Vascular health may be related to the preservation of white matter microstructure early in bipolar disorder. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250019

Serotoninergic psychedelics for schizoaffective disorders. New articles on psilocybin-assisted therapy, BDNF and oxidative stress in autism, and youth bipolar disorder. ➡️https://www.jpn.ca/content/50/4

Fluoxetine substitution for deprescribing antidepressants: A novel fluoxetine substitution protocol offers a safe, practical way to taper SRIs while minimizing risk of withdrawal symptoms. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250054

Switching to a muscarinic agonist: Xanomeline–trospium can alleviate metabolic and neuromotor adverse effects from previous antipsychotic treatment while improving the symptoms of schizophrenia. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250022

Fluoxetine substitution for deprescribing antidepressants: a technical approach. New articles on alleviating adverse effects in schizophrenia, and a safe and practical way to taper SRIs. ➡️https://www.jpn.ca/content/50/4

Decriminalization or more treatment? Recent evidence suggests that the overdose crisis is better addressed by increased treatment access than poorly implemented decriminalization programs. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250084

The manicogenic properties of clozapine: This patient's case highlights a rare case of manic switch and proposes plausible mechanisms of clozapine-induced hypomania. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250048

Familial risk of mood disorders and brain functional connectivity: Connectivity within and between the DMN, CEN, and SN is not a neural indicator of familial risk for major mood disorders. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250002

The manicogenic properties of clozapine: a rare but serious potential adverse effect. New articles on manicogenic properties of clozapine, and familial risk of mood disorders and brain functional connectivity. ➡️https://www.jpn.ca/content/50/3

Hippocampal and amygdala subfield volumes in OCD: Differences in hippocampal and amygdala subfields between people with OCD and healthy controls are dependent on medication status. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.230119

Brain structural and functional impairment in OCD: Combining functional connectivity network mapping with large-scale human brain connectome data. ➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.240145

Brain structural and functional impairment network localization in obsessive–compulsive disorder. New articles on brain structural and functional impairment, and hippocampal and amygdala subfield volumes in OCD. ➡️https://www.jpn.ca/content/50/3

A taxonomy for social cognition: The authors propose an updated biopsychosocial model of social cognition. ➡️ www.jpn.ca/lookup/doi/1...

Brain structural correlates of subclinical body dysmorphic symptoms by gender: Subclinical body dysmorphic symptoms link to brain structure in gender-specific ways. ➡️ www.jpn.ca/lookup/doi/1...

Brain structural correlates of subclinical body dysmorphic symptoms: a gender-informed approach. New articles on subclinical body dysmorphic symptoms, and providing a taxonomy for social cognition. ➡️https://www.jpn.ca/content/50/3

Topiramate for treatment of behavioural disorders in Prader–Willi syndrome: Topiramate is effective in treating compulsive behaviours associated with PWS, but requires monitoring. ➡️ www.jpn.ca/lookup/doi/1...

Greening the lab: Researchers are a group that can take concrete steps to reduce the environmental footprint associated with their activities. ➡️ www.jpn.ca/lookup/doi/1...

Greening the lab: fighting climate change to enhance mental health. New articles on MDD, greening the lab, and topiramate for treatment of behavioural disorders in Prader–Willi syndrome. ➡️https://www.jpn.ca/content/50/2

Patients with MDD with suicidal ideation or attempt show morphological and spontaneous functional impairments compared with those who are not vulnerable to suicide. ➡️ www.jpn.ca/lookup/doi/1...