Editor's Choice: In the era of disease modifying therapies for #SMA, here is a timely topical review discussing treatment and emerging phenotypes. Read the #OpenAccess article here - www.pedneur.com/article/S088... 💪

In this month's issue, Ballabh et al explored T4 treatment of neonates with grade III IVH or periventricular echo density would promote white matter recovery, using magnetic resonance imaging-diffusion tensor imaging metrics to explore the hypothesis. Read Here: buff.ly/HKsWGwd

Language Impairments in Tuberous Sclerosis Complex is common but language evaluations are often delayed. This study examined early vocal development in TSC infants and predictiveness of certain vocal measures for later language outcomes and autism. Read Here: buff.ly/vVW8Oyw

Mineralizing lenticulostiate vasculopathy is an underrecognized risk factor for basal ganglia stroke in toddlers after minor head trauma. Read more in this research about this unique entity and its implications in #PediatricStroke buff.ly/myIUn2J #StrokeAwarenessMonth

What Do We Currently Know About Functional Tic-Like Behaviors: A Topical Review Read more - buff.ly/QzQy61m

Pediatric-Onset Multiple Sclerosis is associated with increased risk of cognitive impairment, especially in early stages of disease. What are the key risk factors and protective factors for these patients? Read Here: buff.ly/kOeFoKy

What are key predictors of various visual impairments in children with unilateral cerebral palsy? A recent study explored markers predictive of specific visual impairments. Read Here: buff.ly/DqNxxX8

Anxiety symptoms are common in children with headache and epilepsy. What is the difference of screening for Generalized Anxiety Disorder using the GAD-2 versus GAD-7 in the clinic? Read Here: buff.ly/34J0rGc

This retrospective review study looks at intrathecal baclofen pump (ITBP) implantation at a single center over a period of 3 years. 43 pediatric patients were implanted with an ITBP. This study analyzed the test dose, the dose-finding process and complications experienced.

Work up for spasmus nutans includes ruling out intracranial space occupying lesions or retinal conditions. While traditionally associated with structural lesions, this case highlights an underlying genetic diagnosis. Can you guess what the genetic diagnosis was?

Learn about the neurological complications of infantile vitamin B12 deficiency in this prospective cohort study from India Read here - buff.ly/EVbH3jy

Avery et al identified risk factors for appointment non-adherence in a pediatric neurology clinic and evaluated the effectiveness of a successful targeted intervention: reminder phone calls. Read Here: buff.ly/ipi0MBg

The April 2026 #pedneuro journal is out! Check out this months 🌟 editor choice🌟 article on developing a proforma for the neonatal neurological examination to increase reliability, accuracy and confidence for pediatricians. Read Here:https://buff.ly/My5gVpT

In SMA, where "time is muscle", can we use prenatal diagnosis to facilitate ultra rapid treatment initiation after birth? Read this short communication that describes two such cases where prenatal diagnosis led to a lead time of 5-8 days, and therefore early treatment planning and start!

About a third of patients with pediatric epilepsy, report at least one barrier in adherence to anti seizure medication. This study by Molisani et al looks at what these barriers are in a large cohort of patients. Medication Barriers in Pediatric Patients With Epilepsy -

What are the educational and social outcomes for patients with optic nerve hypoplasia or septo-optic dysplasia? Salman and colleagues explore this question in the latest issue of #pedneuro journal. Read Here: buff.ly/nXPPvMk

In this month's issue of #pedneuro, Dr. Ronen shares a review article of the impact of the current climate crisis on people with neurodevelopmental disablities. Read Here: buff.ly/OtaP1rp

What is the impact of POLR3 Leukodystrophy on family members? This qualitative study explore the family journey, identifying several areas for child neurologists to provide improved support to patients and families. Read Here: buff.ly/zaKo3rT

Read about the natural history, genotype‒phenotype correlations and prognostic factors in Pediatric Alexander disease in this single center bidirectional cohort study with 81 patients. buff.ly/G297XZE

Etiology of Infantile Epileptic Spasms Syndrome and Clinical Response With Vigabatrin as the First Treatment - buff.ly/9z1M1Md

Learn about Congenital Myasthenic Syndrome type 22 in this study that aimed to identify clinical features, genotypes and treatment responses in a 5 patient cohort with PREPL gene mutation related disease - buff.ly/egMV6H3

Hot Off the Press! Learn how the authors explored AI EEG analysis for predicting ketogenic diet outcomes in pediatric drug resistant epilepsy in his #pedneuro journal article in press. Read Here: buff.ly/B16pTHa

Sleep disorders are common in pediatric insomnia. Few studies have explored additional treatment options beyond melatonin and behavior therapy. This single-center retrospective study evaluated doxepin & mirtazapine efficacy, tolerability & safety in pediatric insomnia. Read Here: buff.ly/bhlcTxx

Do different electrophysiological subtypes of Guillain-Barre Syndrome impact intensive care needs in critically ill children? Bansal et al. explore this question in a retrospective cohort study in this month's #pedneuro issue. Read Here: buff.ly/Xn82rzV

What are some predictors of drug resistant epilepsy (DRE) after perinatal ischemic stroke (PIS)? Fisher et al retrospectively looked at children with PIS and present their insights in this study. Predictors of Drug-Resistant Epilepsy After Perinatal Stroke buff.ly/cYj97Yt

Single center cohort study from China that retrospectively looked at imaging verified acute ischemic stroke (AIS) over 9 years. 14/380 patients with AIS were secondary to mycoplasma pneumoniae. Read about the clinical manifestations & neuroimaging findings in these patients buff.ly/LkPvst6

#OpenAccess X-Linked Creatine Transporter Deficiency (CTD) due to pathogenic variants in SLC6A8 gene is a rare genetic condition affecting approx 35,000 individuals. Vigilian observational study prospectively assessed the natural history & developmental course of CTD Read - buff.ly/5vIMNll

Coffee ☕️ & a Case 🗒️ (Series) explores tactile hallucinations in patients with narcolepsy. Settle in and Read Here: buff.ly/73kOKBY

What is the relationship between perinatal factors, occurrence of cerebral anomalies, and cerebral volumetry? In this study, this question was explored through cerebral term equivalent age MRI. Read Here: buff.ly/YjBWuaJ

Preliminary Outcomes in a Cohort of pediatric patients with multifocal epilepsy treated with central responsive neurostimulation: ⚡️ Reduction in Seizure Frequency 🙂 Improvement in behavior, interactions, and/or academic performance 🛝 Improvements in QOL Read Here: buff.ly/kPBBRZm

“Transition” means more than healthcare. Patients with #DuchenneMuscularDystrophy and their families call for guidance, collaboration, and support across every area of life. Read this topical review from the Special Issue on, “Survivorship in #ChildNeurology” Read more - buff.ly/cxz1Rfe

With measles making a resurgence, read this research from India about biomarkers in Subacute Sclerosing Panencephalitis (SSPE), which is a rare but devastating neurologic complication of measles. buff.ly/sTlxgOZ #PediatricNeurology #Measles #SSPE #Vaccines

Hot off the Press! Read on to explore the extent to which kids and teens with idiopathic intracranial hypertension receive broad multidisciplinary assessments, educational & weight management support. Read Here: buff.ly/zDsLoHb

Read this study from Belgium that explores the genetic landscape of cerebral palsy following perinatal cerebrovascular events Read more - buff.ly/P4fx2uA

Treatment Practices for Infantile Epileptic Spasms Syndrome? Read this Editor's Choice paper from the PERC Infantile Spasms Special Interest Group #InfantileSpasms #Epilepsy buff.ly/4kiM80E

Sunday's ☕ coffee & a case 📋 explores the potential autoimmune involvement in Kleine-Levin Syndrome. Settle in and read here: buff.ly/WhqdbcA

What are the perceptions of clinicians referring to a novel pediatric #neuropalliative clinic? In the latest issue of #pedneuro, Lin et al explores these perceptions. Read here: buff.ly/v2nBte7

Read the latest edition of #pedneuro to explore new insights in the inflammatory and metabolic markers in subacute sclerosing panencephalitis! Read Here: buff.ly/aybGD6O

Saturday's ☕ coffee & 📋 a case explores the use of Mitogen-Activated Proteinkinase Kinase Inhibition for treatment of a facial plexiform neurofibroma in a 6 month old infant. Pour yourself a cup of coffee and settle in to the latest issue of #pedneuro journal! Read here: buff.ly/8AlbZ3v

How can we improve daytime sleepiness in children with narcolepsy? This quality improvement #pedneuro study explores a sleep clinic's initiative, the various interventions they employed and impact they had. Read Here: buff.ly/agkGQiZ

What is the significance of high blood pressure in pediatric onset moya-moya? Find out in this month's issue of #pedneuro as Suliman et al explore this question. Read Here: buff.ly/0cxbwBB

Do Common Genetic Factors Underlie Comorbidity Between Migraine and Major Depressive Disorder in Youth? This study looked at the prevalence and association between migraine and MDD in a large youth sample, and evaluated shared genetic susceptibility amongst the two disorders. buff.ly/2LP5gak

Unforeseen Positive Impacts of a Neonatal Encephalopathy Teleconsultation Program: Insights From Clinicians Practicing in a Rural State Read more: buff.ly/VpvGtUQ #Telemedicine #Neurology #PediatricNeurology

Sunday Edition Coffee ☕ & a Case 📋 highlights the importance of correlating genotype & phenotype for accurate diagnosis & management in patients with atypical presentations of neuro-genetic disorders. Read Here: buff.ly/qB161ef

What are the unexpected impacts of a neonatal encephalopathy tele-consultation program? Read more in the latest #pedneuro issue! Read Here: buff.ly/OUjxuhy

What is the risk for sleep disordered breathing in children with a history of perinatal stroke? Smithson et al. explore the prevalence and associated impact in this #pedneuro issue. Read Here: buff.ly/zZnhGFe

Patient and Caregiver Perspectives on the Transition From Pediatric to Adult Neurology Care: A Single-Site Qualitative Study Read here - buff.ly/7rs7WPt #TransitionofCare #Epilepsy #PediatricNeurology

Sleep Disturbances in Children With Septo-Optic Dysplasia SOD): A Retrospective Cohort Study Read More - buff.ly/ORYDMZc #PediatricNeurology #SleepMedicine #PediatricSleep #BrainMalformations

As the use of few electrode EEGs emerges for quick seizure detection in emergency rooms, is there a difference between using centroparietal (CP) vs frontotemporal (FT) two channel electrode montages? This study looks into this question - buff.ly/BJykv3D #OpenAccess #Epilepsy #EEGs