Tom Kalil and Renaissance Philanthropy argue that philanthropy lacks the specialised institutional vehicles its hardest problems demand. They are right. But their framework exposes a deeper question.

Iterum got FDA approval. 18 months later, it shut down. Antibiotics that should be held in reserve are forced into volume markets. I call this the reserve transmission gap. Paper here: papers.ssrn.com/sol3/papers....

Working in Monaco has sheltered me from the realities of the real world...for a few days at least...

If you ever doubt whether you could be a great leader, remember that the global economy now depends on a 23-mile stretch of water. Structural failure rarely arrives as a mistake. It arrives as a system that was never designed with fragility in mind.

Exactly 😂

As someone who was born in Handsworth this warms my heart ❤️

The science of racism with Professor Keon West

The thing about writing is that it never feels finished.

Ah well onto the next platform we go...

Active conflicts are creating conditions that accelerate antimicrobial resistance fastest. The institutions needed to govern antibiotics as a strategic asset are often the same ones driving those conflicts. That is not an accusation. It is a governance design problem with no ceasefire solution.

Same for other democracies too

🎵in violent times, you shouldn’t have to sell your soul🎵

We are either becoming more resilient or complacent

I remember when ‘Brexit Means Brexit’ became a way for silly people to insist that they supported something they could neither justify nor explain. Obviously the context is very different, but something similar is already happening with the ‘war’ in Iran. And it’s mostly the same people doing it.

Focus on controlling your controllables

Let myself down my saying “the science” 😔

Medicine is transitioning from: Therapeutic Era (products solve problems) → Capability Era (systems must preserve options)

My new working paper: Antibiotics as reserve assets. Diagnostics as monetary policy. The missing central banking architecture for AMR governance. I am sharing it to invite critique, discussion, and engagement papers.ssrn.com/sol3/papers.... #AMR #HealthPolicy #InfectiousDiseases

My new working paper: Antibiotics as reserve assets. Diagnostics as monetary policy. The missing central banking architecture for AMR governance. I am sharing it to invite critique, discussion, and engagement papers.ssrn.com/sol3/papers.... #AMR #HealthPolicy #InfectiousDiseases

The system doesn’t survive because of bad actors. It survives because good ones stop asking what they’re complicit in.

The deeper the thinking, the smaller the room tends to get.

Stepped away for a few months to focus on longer writing. Feels good to be back to shorter, unfinished thoughts again :)

I was invited to tour the new PHTA building in Birmingham yesterday. A great set up and an opportunity for Birmingham Life Sciences and healthcare sector to further their collaborative efforts. Unfortunately, attracting such opportunities is difficult when money is being sucked out of the UK

Yes. Global health is not a cost to cut, it’s a smart investment in keeping people (including in your country, including your own family) safe from danger. ➡️ www.telegraph.co.uk/global-healt...

“The decision to close the Fleming Fund was not accompanied by an official statement or press release.” www.thelancet.com/journals/lan...

We need to go back to the days when politics was boring, and no-one really cared

Most nights I reflect on how much humanity has changed since 2019. Absolutely crazy 🤯

Antibiotic stewardship: bold plan on paper, total flop in practice?

For scientists who want to shift the public narrative, there are really only two paths: rebel or lead

The relocation of the EMA HQ from London quietly reshaped the landscape of UK science following Brexit and the ripple effects remain 😔

Monaco

Many a “career” is still relying on Covid opinion

I now avoid any podcast involving someone smoking a cigar 🚩🚩🚩

Looking forward to a summer holiday in "freeloading," "pathetic" Europe. The original idea was to go to America. Went off that idea.

To successfully rally public support for increased taxation of the wealthy, we must fundamentally change tax systems

If Europe wants to position itself to the world as more reliable than the US, having Ukraine as its only distinguisher won’t fly - if that is funded by gutting global cooperation, & run in parallel with greenlighting an end to Gaza, it positions Europe as valuing white lives only.

Spent a nice day in the sun at our 🎾 clay courts watching Dan Evans practice

I’ve been hearing a lot about “free speech” online over the past couple of years, but we’re moving into a time when actual free speech is going to be (1) hard, and (2) really matter.

It's stuff like this that causes distrust in politicians which leads to the likes of trump getting into power

I had a vague understanding of our Fijian roots, but today's conversation with my grandad unveiled their true significance, With my ancestors landing on the islands in the late 1800s. I now feel an incredibly strong bond with the islands I've never visited.

Staying at Coombes Abbey Hotel in Coventry. A colleague comes down for breakfast as pale as a ghost...after apparently experiencing paranormal activity all night

That's true. If not for him I wouldn't have rediscovered RSS, podcasts, and books.

On the plus side, Elon killed our Twitter addiction

The struggle is real: trying to eat anything but chocolate, and ending by eating the chocolate anyway

spot on, Shaggy #RealMonsters #MonstersInc

Failure is an event, not a person

Idiot

Solo living, separation from society, reliance on technology and influenced by tech oligarchs

Understanding is built from the inside out. While external input plays a role, the essence of learning lies in the individual's power to generate and test ideas. This internal process of conjecturing makes learning a sovereign act.

Funnily enough, people that are extremely unkind to me in person usually have some sort of "be kind" statement on their social media profiles 🥸