Our preprint on chromatin accessibility changes in response to DNA-damaging agents in cardiomyocytes is now published. Congrats to Renee et al and two first time co-authors! [1/3] journals.plos.org/plosgenetics...

Happy to be at ASHG! 2 students in the lab will present posters on gene regulatory evolution in primates on Thurs: Emma focuses on responses to stimuli: 9109T John focuses on transposable elements: 6036T Please stop by if interested #ASHG25

Project led by Sayan investigating the effects of CX-5461, an anti-cancer drug currently in clinical trials, on cardiomyocytes: ‘Topoisomerase II inhibitors CX-5461 and Doxorubicin differ in their cardiotoxicity profiles.’ [1/4] www.biorxiv.org/content/10.1...

Happy to share our work led by Renee: ‘Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci.’ www.biorxiv.org/content/10.1...

Happy to share the published version of Omar & Sayan’s paper. We generated a DNA-damage-associated cardiomyocyte protein co-expression network to gain insights into tolerance to genetic variation and disease. www.sciencedirect.com/science/arti...

Come join us at #ASHG25 in Boston Oct 14-18! Abstract submission site (ashg.org/submit) is now live. Abstracts due June 9th.