We study the genetics of drug efficacy using longitudinal biomarker and medication prescription data from #EHRs. 🧬💊 Have a look at the 🧵 on i) modelling drug response and biomarker progression, ii) using #PRS to predict efficacy and iii) the challenges with #EHRs. www.nature.com/articles/s41...

Tissue-specific co-expression networks to identify key genes 🧬 Have a look at Patrick's thread that explains how Downstreamer can link common genetic variation to rare diseases. Thank you for including Zoltán and me on this project!