🥳We're proud to share that the International Journal of Antimicrobial Agents has achieved a 2025 Impact Factor of 5.0, up from 4.6 in 2024. A sincere thank you to our authors, reviewers, editors and readers! @isacworld.bsky.social

New study: Stepwise cefiderocol exposure in NDM-producing Klebsiella pneumoniae selected recurrent baeS variants and reshaped iron uptake, porin expression, blaNDM-5, and biofilm responses. www.sciencedirect.com/science/arti... @isacworld.bsky.social

New IJAA study tracks in vivo tigecycline resistance in ST540 CRAB, revealing adeS N125S-driven AdeABC upregulation, collateral sensitivity to cefoperazone/sulbactam, and ICU transmission. www.sciencedirect.com/science/arti... @isacworld.bsky.social

MALDI-TOF MS combined with machine learning accurately predicts ceftriaxone resistance in Salmonella (ROC-AUC up to 0.924). This interpretable, web-based approach could accelerate targeted therapy and strengthen antimicrobial stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

New in IJAA (Vol.67, Issue 7): AI-guided AMR prediction, emerging CZA–cefiderocol cross-resistance, phage therapy advances, polymyxin B PK, and cefiderocol clinical evidence. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

Using 5,239 Klebsiella pneumoniae genomes, a machine learning model accurately predicted multi-level antimicrobial resistance for 11 antibiotics (mean AUC >0.9), advancing precision therapy and AMR control. www.sciencedirect.com/science/arti... @isacworld.bsky.social

IJAA Volume 67 Issue 6 features the latest advances in AMR, AI-guided infection prediction, CRKP resistance, phage therapy, anti-biofilm strategies, and antimicrobial PK/PD optimization. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

Repurposing sulfamethoxazole through gold nanocluster modification: SMZ_Au NCs showed potent antibacterial and anti-biofilm activity against MDR Gram-negative bacteria, with promising in vivo efficacy and safety. www.sciencedirect.com/science/arti... @isacworld.bsky.social

AI + MALDI-TOF MS rapidly predicted antimicrobial resistance in Acinetobacter baumannii infection with >83% accuracy, supporting faster AI-assisted AST in clinical practice. www.sciencedirect.com/science/arti... @isacworld.bsky.social

IJAA Volume 67, Issue 5 is now online, featuring advances in phage therapy, AMR prediction, resistance mechanisms, PK/PD, and antimicrobial stewardship. Explore the latest updates in infectious diseases research. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

SMART ML model predicts postoperative infection risk (AUC 0.86), enabling targeted prevention and antimicrobial stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

China hospital antibiotic use fell (46.8→35.3 DDDs/100 PDs, 2013–2024), but shifts to Watch/Reserve raise AMR risks. By 2030, use may drop 11.4%, highlighting need for targeted stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

Phage–colistin synergy depends on order: phage-first enhances killing, colistin-first weakens phage. Only simultaneous use suppresses resistance in MDR A. baumannii. www.sciencedirect.com/science/arti... @isacworld.bsky.social

Cefiderocol resistance emerging in China: blaNDM-carrying E. coli shows high resistance via CirA/PBP3 mutations, with clonal spread risk. Urgent need for One Health surveillance. www.sciencedirect.com/science/arti... @isacworld.bsky.social

Imagine viruses that fight bacteria instead of causing disease—phages are doing just that! From hospitals to farms to crops, One Health approach is turning phage therapy into a real-world weapon against AMR. www.sciencedirect.com/science/arti... #PhageTherapy #OneHealth @isacworld.bsky.social

Can phages, probiotic strains & host‑directed therapies reshape our fight against AMR? 🦠 👀 Check them out in the latest research: www.sciencedirect.com/journal/inte... #AMR #InfectiousDiseases #PhageTherapy #Antimicrobials #HostDirectedTherapy @isacworld.bsky.social

🚨 Hot Topic Artificial intelligence and machine learning are transforming antimicrobial research—accelerating drug discovery, improving resistance prediction and enabling precision therapy to outpace superbugs. www.sciencedirect.com/science/arti... #AMR #AI #machinelearning @isacworld.bsky.social

📣 Join the Editorial Team! The International Journal of Antimicrobial Agents is looking for Associate Editors, Statistical Advisors, and Editors-in-Training to help shape the future of antimicrobial research and publishing. Learn more: www.sciencedirect.com/journal/inte... @isacworld.bsky.social

One month into 2026 — and the science is already accelerating... From model-informed precision dosing and AI-driven safety prediction to phage therapy, resistance genomics, and novel antimicrobials Check them out👉 www.sciencedirect.com/journal/inte... @isacworld.bsky.social

Take a look at our ISAC News and Information Page! www.sciencedirect.com/science/arti... Member perks-reduced IJAA subscription, conferences/workshops registration, project/travel grants Working groups-Join us and/or propose new groups Watch on-demand webinars and short videos @isacworld.bsky.social

It is happening in the next few hours. See you soon~

Join us for a special ISAC session marking One Health Awareness Month! 🌍 Launching “One Health” Special Issue and exploring how human, animal & environmental health are all connected in the fight against AMR. Register now us02web.zoom.us/webinar/regi... @isacworld.bsky.social #OneHealth #AMR

💊 tet(X4) Resistance in Klebsiella| IJAA Vol.67 Issue 1 (In progress) Global One Health dissemination of tet(X4) via mobile plasmids, often co-existing with carbapenem and colistin resistance, signals a serious public health risk. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

💊 Phage Depolymerases vs hvKP | IJAA Vol.67 Issue 1 (In progress) TFP41 and TSP42 strip the K2 capsule of hypervirulent K. pneumoniae, enhance immune clearance, and deliver up to 100% survival in murine pneumonia models. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

💊 Predicting AKI in Glycopeptide Therapy | IJAA Vol.67 Issue 1 (In progress) An explainable XGBoost model predicts vancomycin- and teicoplanin-associated AKI, enabling early, personalized risk assessment. 📖 doi.org/10.1016/j.ij... @isacworld.bsky.social

💊 Prophage Activation & Antibiotics | IJAA Vol.67 Issue 1 (In progress) A brief review of how antibiotics drive or inhibit prophage induction, influence toxin release and gene transfer, and guide safer therapy decisions. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🌍 Nanomedicine for Phage Therapy | IJAA Vol.67 Issue 1 (In progress) A concise review of how nanoparticles, liposomes, hydrogels and nanofibers enhance phage stability, delivery and efficacy against MDR pathogens. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🚀 IJAA Vol. 66 Issue 6 is out! Highlights: global AMR burden, MRSA, One Health, AI strategies, and the Global Landscape of Phage Therapy. 📖 www.sciencedirect.com/journal/inte... @isacworld.bsky.social

🌍 Commercial Phage Therapy Prospects| IJAA Vol.66 Issue 6 (In progress) Analysis reveals a surge in phage therapy patents & clinical trials, yet post-approval regulatory & economic hurdles remain for commercial success. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🌍 Global Landscape of Phage Therapy | IJAA Vol.66 Issue 6 An international survey uncovers clinicians’ perspectives on phage therapy, revealing growing optimism, diverse experiences, and global challenges in clinical adoption. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🤖 AI Strategies to Combat AMR | IJAA Vol.66 Issue 5 Whole genome-based machine learning predicts AMR in nontyphoidal Salmonella, providing genomic insights to enhance AI-driven surveillance and precision control. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🌏 Hot Topic | IJAA Vol.66 Issue 5 Survey finds 97% of Australian ID physicians would use phage therapy if safety standards are met, highlighting its promise against drug-resistant infections and priorities for clinical use. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

🌍 IJAA Vol.66, Issue 5 Hot Topic: Phage therapy in Australia. AMR highlights: WGS-based AMR prediction, polymyxin B synergy vs P. aeruginosa, CREC in China, Raman AI for MRSA/CRKP, CRKP in Portugal. 📖 www.sciencedirect.com/journal/inte... #IJAA #AMR @isacworld.bsky.social

Explore the latest from IJAA (Vol. 66, Issue 4)! 🦠 Phage therapy: models & clinical use 🧬 Klebsiella resistance evolution 💊 Cefiderocol & β-lactamase detection 🔬 Serum lipids modulating S. aureus phage sensitivity 📈 Vancomycin dosing in the critically ill @isacworld.bsky.social

📢 New in IJAA Vol. 66, Issue 1! 🧬 AMR in the rumenofaecobiome 💊 Posaconazole in rare IFIs 🦠 IFN-λ in respiratory models 💉 Tigecycline modulates sepsis immunity 🌍 Global CRE resistance patterns 🧪 CRISPR assay for GES β-lactamase 📖 Read: www.sciencedirect.com/journal/inte...

Check out the latest issue! Dive into groundbreaking research on host-directed therapies, antimicrobial mechanism, multiomics informed mathematical model and the spread of antimicrobial-resistant pathogens Read now: www.sciencedirect.com/journal/inte... @isacworld.bsky.social