@ijaa-isac.bsky.social
📤 12
📥 2
📝 31
Repurposing sulfamethoxazole through gold nanocluster modification: SMZ_Au NCs showed potent antibacterial and anti-biofilm activity against MDR Gram-negative bacteria, with promising in vivo efficacy and safety.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Repurposing sulfamethoxazole via gold nanocluster modification for antibacterial and anti-biofilm activity against multidrug-resistant Gram-negative bacteria
The global spread of antimicrobial resistance represents a severe threat to public health, with infections caused by multidrug-resistant Gram-negative…
https://www.sciencedirect.com/science/article/pii/S0924857926000464
3 days ago
0
0
0
AI + MALDI-TOF MS rapidly predicted antimicrobial resistance in Acinetobacter baumannii infection with >83% accuracy, supporting faster AI-assisted AST in clinical practice.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Development and validation of a predictive model for profiling antibiotic resistance phenotypes of Acinetobacter baumannii strains via clinical MALDI-TOF mass spectra: A multicenter study
Acinetobacter baumannii is a significant pathogen responsible for healthcare-acquired infections (HAIs), posing challenges due to its rising resistanc…
https://www.sciencedirect.com/science/article/abs/pii/S092485792600049X
11 days ago
0
1
1
IJAA Volume 67, Issue 5 is now online, featuring advances in phage therapy, AMR prediction, resistance mechanisms, PK/PD, and antimicrobial stewardship. Explore the latest updates in infectious diseases research.
www.sciencedirect.com/journal/inte...
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 67, Issue 5, May 2026 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/5
15 days ago
0
1
1
SMART ML model predicts postoperative infection risk (AUC 0.86), enabling targeted prevention and antimicrobial stewardship.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Surgical MAchine learning model for predicting Risk of postoperative infecTions in general elective surgery (SMART): A modelling study
To apply a machine learning (ML) model that we developed and internally validated for predicting postoperative infection likelihood after elective gen…
https://www.sciencedirect.com/science/article/pii/S0924857926000579
20 days ago
0
2
1
China hospital antibiotic use fell (46.8→35.3 DDDs/100 PDs, 2013–2024), but shifts to Watch/Reserve raise AMR risks. By 2030, use may drop 11.4%, highlighting need for targeted stewardship.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Present trajectories to forecasted future: A longitudinal analysis of hospital antibiotic use in China from 2013 to 2024 and projections to 2030
To characterize the decadal trends in antibiotic use among hospitalized patients in China, and to project consumption trajectories through 2030.We ana…
https://www.sciencedirect.com/science/article/pii/S0924857926000531
about 1 month ago
0
1
1
Phage–colistin synergy depends on order: phage-first enhances killing, colistin-first weakens phage. Only simultaneous use suppresses resistance in MDR A. baumannii.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Treatment sequences of a phage and colistin combination trigger different evolution pathways of a multidrug-resistant Acinetobacter baumannii yielding distinct treatment outcomes
To better understand the underlying mechanisms of treatment order of phage and antibiotic synergy (PAS), particularly in the context of planktonic bac…
https://www.sciencedirect.com/science/article/pii/S0924857926000348
about 1 month ago
0
0
0
Cefiderocol resistance emerging in China: blaNDM-carrying E. coli shows high resistance via CirA/PBP3 mutations, with clonal spread risk. Urgent need for One Health surveillance.
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Molecular mechanisms and clonal distribution of cefiderocol-resistant blaNDM-carrying Escherichia coli: A multi-centre study in China
Reports on cefiderocol resistance are increasing globally despite its unavailability in China. The blaNDM-carrying Escherichia coli was one of the mos…
https://www.sciencedirect.com/science/article/abs/pii/S0924857926000518
about 1 month ago
0
1
1
Imagine viruses that fight bacteria instead of causing disease—phages are doing just that! From hospitals to farms to crops, One Health approach is turning phage therapy into a real-world weapon against AMR.
www.sciencedirect.com/science/arti...
#PhageTherapy
#OneHealth
@isacworld.bsky.social
loading . . .
Phage therapy in China: Arming the One Health approach
https://www.sciencedirect.com/science/article/pii/S0924857926000208
about 2 months ago
0
0
0
Can phages, probiotic strains & host‑directed therapies reshape our fight against AMR? 🦠 👀 Check them out in the latest research:
www.sciencedirect.com/journal/inte...
#AMR
#InfectiousDiseases
#PhageTherapy
#Antimicrobials
#HostDirectedTherapy
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 67, Issue 3, March 2026 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/3
about 2 months ago
0
0
0
🚨 Hot Topic Artificial intelligence and machine learning are transforming antimicrobial research—accelerating drug discovery, improving resistance prediction and enabling precision therapy to outpace superbugs.
www.sciencedirect.com/science/arti...
#AMR
#AI
#machinelearning
@isacworld.bsky.social
loading . . .
Artificial intelligence and machine learning in antimicrobial discovery, resistance prediction, and precision therapy
The global crisis of antimicrobial resistance (AMR) demands a paradigm shift in traditional drug discovery, and artificial intelligence (AI) is unique…
https://www.sciencedirect.com/science/article/pii/S092485792600004X
2 months ago
0
2
1
📣 Join the Editorial Team! The International Journal of Antimicrobial Agents is looking for Associate Editors, Statistical Advisors, and Editors-in-Training to help shape the future of antimicrobial research and publishing. Learn more:
www.sciencedirect.com/journal/inte...
@isacworld.bsky.social
loading . . .
Announcements - International Journal of Antimicrobial Agents | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/about/announcements
2 months ago
0
1
0
One month into 2026 — and the science is already accelerating... From model-informed precision dosing and AI-driven safety prediction to phage therapy, resistance genomics, and novel antimicrobials Check them out👉
www.sciencedirect.com/journal/inte...
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 67, Issue 1, January 2026 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/1
3 months ago
0
2
2
Take a look at our ISAC News and Information Page!
www.sciencedirect.com/science/arti...
Member perks-reduced IJAA subscription, conferences/workshops registration, project/travel grants Working groups-Join us and/or propose new groups Watch on-demand webinars and short videos
@isacworld.bsky.social
loading . . .
International Society of Antimicrobial Chemotherapy (ISAC) News and Information Page
https://www.sciencedirect.com/science/article/pii/S0924857925002432
4 months ago
0
0
0
It is happening in the next few hours. See you soon~
add a skeleton here at some point
4 months ago
0
0
0
Join us for a special ISAC session marking One Health Awareness Month! 🌍 Launching “One Health” Special Issue and exploring how human, animal & environmental health are all connected in the fight against AMR. Register now
us02web.zoom.us/webinar/regi...
@isacworld.bsky.social
#OneHealth
#AMR
4 months ago
0
1
2
💊 tet(X4) Resistance in Klebsiella| IJAA Vol.67 Issue 1 (In progress) Global One Health dissemination of tet(X4) via mobile plasmids, often co-existing with carbapenem and colistin resistance, signals a serious public health risk. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Genome-wide insight into the evolution and global transmission of tigecycline resistant tet(X4)-carrying Klebsiella species across reservoirs
The emergence of plasmid mediated tet(X4) gene compromises the clinical utility of tigecycline and underscores growing concerns regarding its environm…
https://www.sciencedirect.com/science/article/abs/pii/S0924857925002201
5 months ago
1
4
3
💊 Phage Depolymerases vs hvKP | IJAA Vol.67 Issue 1 (In progress) TFP41 and TSP42 strip the K2 capsule of hypervirulent K. pneumoniae, enhance immune clearance, and deliver up to 100% survival in murine pneumonia models. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Two Tail Protein-Derived Capsule Depolymerases From Phage vB_KpnS_GH-K1 are Effective Against Pneumonia Caused by K2 Serotype Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKP) poses an escalating threat to public health and animal husbandry, underscoring the urgent need for novel an…
https://www.sciencedirect.com/science/article/pii/S0924857925002171
5 months ago
0
0
0
💊 Predicting AKI in Glycopeptide Therapy | IJAA Vol.67 Issue 1 (In progress) An explainable XGBoost model predicts vancomycin- and teicoplanin-associated AKI, enabling early, personalized risk assessment. 📖
doi.org/10.1016/j.ij...
@isacworld.bsky.social
loading . . .
Redirecting
https://doi.org/10.1016/j.ijantimicag.2025.107651
5 months ago
0
1
1
💊 Prophage Activation & Antibiotics | IJAA Vol.67 Issue 1 (In progress) A brief review of how antibiotics drive or inhibit prophage induction, influence toxin release and gene transfer, and guide safer therapy decisions. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Antibiotic-mediated prophage activation: Mechanisms, consequences, and therapeutic implications
Prophages, as an integral part of bacterial genomes, play a pivotal role in regulating host virulence and shaping bacterial evolution. Exposure to ant…
https://www.sciencedirect.com/science/article/pii/S0924857925002109
5 months ago
0
0
0
🌍 Nanomedicine for Phage Therapy | IJAA Vol.67 Issue 1 (In progress) A concise review of how nanoparticles, liposomes, hydrogels and nanofibers enhance phage stability, delivery and efficacy against MDR pathogens. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Nanomedicine for phage therapy: Encapsulation strategies for enhanced antimicrobial efficacy
Antibiotic resistance is a growing global health crisis, driving the need for alternative antimicrobial strategies. Phage therapy has re-emerged as a …
https://www.sciencedirect.com/science/article/pii/S0924857925002158
6 months ago
0
1
0
🚀 IJAA Vol. 66 Issue 6 is out! Highlights: global AMR burden, MRSA, One Health, AI strategies, and the Global Landscape of Phage Therapy. 📖
www.sciencedirect.com/journal/inte...
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 66, Issue 6, December 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/66/issue/6
6 months ago
0
0
0
🌍 Commercial Phage Therapy Prospects| IJAA Vol.66 Issue 6 (In progress) Analysis reveals a surge in phage therapy patents & clinical trials, yet post-approval regulatory & economic hurdles remain for commercial success. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
The prospect of approved and commercially available phage therapeutics
As antibiotic resistance of bacterial pathogens spreads, interest in bacteriophage (phage) therapy has soared again in many countries. Currently, ther…
https://www.sciencedirect.com/science/article/pii/S0924857925001670
6 months ago
0
1
0
🌍 Global Landscape of Phage Therapy | IJAA Vol.66 Issue 6 An international survey uncovers clinicians’ perspectives on phage therapy, revealing growing optimism, diverse experiences, and global challenges in clinical adoption. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Phage therapy: An international survey of attitudes and experiences amongst clinicians
Phage therapy is a promising tool to combat the global threat of antimicrobial resistance. Clinicians, as part of interdisciplinary teams, play an int…
https://www.sciencedirect.com/science/article/pii/S0924857925001827
6 months ago
0
2
1
🤖 AI Strategies to Combat AMR | IJAA Vol.66 Issue 5 Whole genome-based machine learning predicts AMR in nontyphoidal Salmonella, providing genomic insights to enhance AI-driven surveillance and precision control. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
loading . . .
Genomic insights into nontyphoidal Salmonella: Prediction of antimicrobial resistance with whole genome-based machine learning
Nontyphoidal Salmonella is a world-leading foodborne pathogen associated with an increased rate of antimicrobial resistance (AMR) and remains endemic …
https://www.sciencedirect.com/science/article/abs/pii/S092485792500130X
7 months ago
0
2
1
🌏 Hot Topic | IJAA Vol.66 Issue 5 Survey finds 97% of Australian ID physicians would use phage therapy if safety standards are met, highlighting its promise against drug-resistant infections and priorities for clinical use. 📖
www.sciencedirect.com/science/arti...
@isacworld.bsky.social
8 months ago
0
0
0
🌍 IJAA Vol.66, Issue 5 Hot Topic: Phage therapy in Australia. AMR highlights: WGS-based AMR prediction, polymyxin B synergy vs P. aeruginosa, CREC in China, Raman AI for MRSA/CRKP, CRKP in Portugal. 📖
www.sciencedirect.com/journal/inte...
#IJAA
#AMR
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 66, Issue 5, November 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/66/issue/5
8 months ago
0
0
0
Explore the latest from IJAA (Vol. 66, Issue 4)! 🦠 Phage therapy: models & clinical use 🧬 Klebsiella resistance evolution 💊 Cefiderocol & β-lactamase detection 🔬 Serum lipids modulating S. aureus phage sensitivity 📈 Vancomycin dosing in the critically ill
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 66, Issue 4, October 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/66/issue/4
9 months ago
0
1
0
📢 New in IJAA Vol. 66, Issue 1! 🧬 AMR in the rumenofaecobiome 💊 Posaconazole in rare IFIs 🦠 IFN-λ in respiratory models 💉 Tigecycline modulates sepsis immunity 🌍 Global CRE resistance patterns 🧪 CRISPR assay for GES β-lactamase 📖 Read:
www.sciencedirect.com/journal/inte...
loading . . .
International Journal of Antimicrobial Agents | Vol 66, Issue 1, July 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/66/issue/1
10 months ago
1
1
1
Check out the latest issue! Dive into groundbreaking research on host-directed therapies, antimicrobial mechanism, multiomics informed mathematical model and the spread of antimicrobial-resistant pathogens Read now:
www.sciencedirect.com/journal/inte...
@isacworld.bsky.social
loading . . .
International Journal of Antimicrobial Agents | Vol 65, Issue 6, June 2025 | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/65/issue/6
about 1 year ago
0
5
2
you reached the end!!
feeds!
log in