I'm so glad you said this, because about 30 seconds ago, I published a newsletter piece detailing how conservatives have dump-trucked through all of the previously established common sense, nuanced, compromise positions on trans rights to get here: burns-notice.ghost.io/what-would-t...

strongest earthquake i can remember in a long time

As usual with this issue, Harris is calling for a compromise that already exists. Every sporting body has standards for how long athletes must be on hormones before they can compete as women. The problem isn’t that we’re ignoring ‘reasonable concerns,’ the problem is that republicans are lying.

requiring applicants to not only manually re-enter most of their transcript but also track down a course catalog to copy and paste course descriptions for dozens of courses from years to decades ago is absurd

wish i could just spend all day cloning

I will grudgingly admit that it is occasionally nice to spend a sunday morning reading Nevada and watching movies instead of being in the cell culture room

I'm happy people can read the final version of this paper! See what happens when we detach heterochromatin from the nuclear periphery in mouse stem cells:

And yep - we found that the nuclear membrane protein LAP2b cooperates with lamin B1 to maintain nuclear integrity. When both are depleted, we see lamina defects and nuclear ruptures that look like this (cyan is nuclear lamina, magenta is nuclear integrity reporter): (5/n)

The nuclear lamina strengthens the nucleus and organizes the genome. So what happens when you acutely degrade it in living cells? Not what we thought! (1/n) www.molbiolcell.org/doi/10.1091/...