Michael Payne
@mjohnpayne.bsky.social
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Senior Research Fellow at University of Sydney. Microbial genomics, Bioinformatics and Python!
Finally a preprint for our tool DAMPA (Australiana included) that generates efficient probe panels for targeted metagenomics from pangenome graphs. Presented at ABPHM and ABACBS last year.
www.medrxiv.org/content/10.6...
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DAMPA - accelerated and simplified design of probe panels for targeted metagenomics using pangenome graphs
Targeted metagenomics, where samples are enriched for multiple organisms of interest using oligonucleotide probes, is a highly efficient sequencing methodology that is becoming standard practice for g...
https://www.medrxiv.org/content/10.64898/2026.05.15.26352859v1
about 2 months ago
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reposted by
Michael Payne
David Ma
8 months ago
Great talk from Michael Payne at
#ABACBS2025
on DAMPA - tool for designing probe panels for targeted metagenomics using pangenome graphs! Captures all diversity efficiently, uses fewer probes than competitors. Critical for syndromic surveillance! 🧬🔬
#Metagenomics
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Had a great time at
#ABPHM
where I presented our new tool
github.com/Multipathoge...
. DAMPA uses pangenome graphs to design targeted metagenomics probe panels that minimise probe number while retaining very high target coverage. Preprint coming soon!
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GitHub - MultipathogenGenomics/dampa: Dampa: Diversity Aware Metagenomic Panel Assignment
Dampa: Diversity Aware Metagenomic Panel Assignment - MultipathogenGenomics/dampa
https://github.com/MultipathogenGenomics/dampa
about 1 year ago
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